MX356239B - N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same. - Google Patents

N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same.

Info

Publication number
MX356239B
MX356239B MX2013001055A MX2013001055A MX356239B MX 356239 B MX356239 B MX 356239B MX 2013001055 A MX2013001055 A MX 2013001055A MX 2013001055 A MX2013001055 A MX 2013001055A MX 356239 B MX356239 B MX 356239B
Authority
MX
Mexico
Prior art keywords
imidazo
phenyl
compounds
obtaining
nonamide
Prior art date
Application number
MX2013001055A
Other languages
Spanish (es)
Other versions
MX2013001055A (en
Inventor
Alejandro Bucio Cano José
Mahuampi Montenegro Sustaita Mabel
Romualda Reyes Arellano Alicia
Original Assignee
Inst Politecnico Nacional
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Politecnico Nacional filed Critical Inst Politecnico Nacional
Priority to MX2013001055A priority Critical patent/MX356239B/en
Publication of MX2013001055A publication Critical patent/MX2013001055A/en
Publication of MX356239B publication Critical patent/MX356239B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

The present invention is related to the compounds: N-[4-phenyl-(imidazo-2-yl)]-hexanamide of formula (I) and N-[4-phenyl-(imidazo-2-yl)]-nonamide of formula (II) and process for obtaining the same. These compounds are obtained by a two-step process: the first step includes the acylation of the 4-aminobenzonitrile with the hexanoic and nonanoic acids and thionyl chloride in a DMA for obtaining the amides of formulas (III) and (IV) in quantitative yield. The second step includes a cyclization, which is performed by a reaction with ethylenediamine and carbon disulfide. The two compounds have been evaluated against Chromobacterium violaceum and it was observed that both compounds reduced the production of violacein, which production involves antiquorum sensing activity.
MX2013001055A 2013-01-25 2013-01-25 N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same. MX356239B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MX2013001055A MX356239B (en) 2013-01-25 2013-01-25 N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2013001055A MX356239B (en) 2013-01-25 2013-01-25 N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same.

Publications (2)

Publication Number Publication Date
MX2013001055A MX2013001055A (en) 2014-07-25
MX356239B true MX356239B (en) 2018-05-17

Family

ID=51830097

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013001055A MX356239B (en) 2013-01-25 2013-01-25 N-[4-phenyl-(imidazo-2-yl)]-hexanamide and n-[4-phenyl-(imidazo-2 -yl)]-nonamide and process for obtaining the same.

Country Status (1)

Country Link
MX (1) MX356239B (en)

Also Published As

Publication number Publication date
MX2013001055A (en) 2014-07-25

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