MX351117B - Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein. - Google Patents

Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein.

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Publication number
MX351117B
MX351117B MX2011002098A MX2011002098A MX351117B MX 351117 B MX351117 B MX 351117B MX 2011002098 A MX2011002098 A MX 2011002098A MX 2011002098 A MX2011002098 A MX 2011002098A MX 351117 B MX351117 B MX 351117B
Authority
MX
Mexico
Prior art keywords
glycyrrhizic
cancer
well
papilloma virus
human papilloma
Prior art date
Application number
MX2011002098A
Other languages
Spanish (es)
Other versions
MX2011002098A (en
Inventor
Esther Dragustinovis Ruiz María
Original Assignee
Desarrollos Vph S A De C V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Desarrollos Vph S A De C V filed Critical Desarrollos Vph S A De C V
Priority to MX2011002098A priority Critical patent/MX351117B/en
Publication of MX2011002098A publication Critical patent/MX2011002098A/en
Publication of MX351117B publication Critical patent/MX351117B/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention refers to a novel formulation of ammonium salts of glycyrrhizic compounds such as glycyrrhizin, glycyrrhizic acid or glycyrrhetinic acid in a thermo reversible gel of the polyoxyethylene-polyoxypropylene-polyoxyethylene type as a vehicle at a 25% concentration, the compound being previously dissolved in propylene glycol as an absorption dissolvent or enhancer, at a compound concentration of from about 10, 20, 100mg/ml and to about 200 mg/ml of the active agent of the ammonium salts of glycyrrhizic acid; the compound includes a preserving agent such as methylparaben at a concentration of 0.1%, once the formulation is finished, the trichloroacetic acid being added at a cocnentration of 0.5 to 5.0% and finally the ph is maintained at a rate of 3-7, preferably at 3-5 due to physiological characteristics at a vaginal level. The invention is useful for the treatment of high and low grade intraepithelial squamous lesions related to Human Papilloma Virus recurrent infect ions of high and low oncogenic risk located at the inner and outer genital area such as cervix and vagina, and vulva, penis, anus, and rectum respectively, as well as cancer present in the aforementioned anatomic al regions in men and women.
MX2011002098A 2011-02-25 2011-02-25 Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein. MX351117B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MX2011002098A MX351117B (en) 2011-02-25 2011-02-25 Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2011002098A MX351117B (en) 2011-02-25 2011-02-25 Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein.

Publications (2)

Publication Number Publication Date
MX2011002098A MX2011002098A (en) 2012-08-29
MX351117B true MX351117B (en) 2017-10-03

Family

ID=47225237

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011002098A MX351117B (en) 2011-02-25 2011-02-25 Salt formulation of glycyrrhizic compounds in thermo reversible gel and trichloroacetic acid as a keratolytic topically applied in the genital tract in males and females with lesions caused by human papilloma virus infections as well as cancer therein.

Country Status (1)

Country Link
MX (1) MX351117B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017010806A (en) * 2017-08-22 2018-01-18 Atso Corp Affairs S A De C V Formulation of 18-beta-glicirretinic acid in combination with revesterol and metformin, uses and manufacturing method thereof.
MX2019009482A (en) * 2019-08-08 2021-02-09 Proyectos Atso S A P I De C V PHARMACEUTICAL FORMS OF 18ß-GLICIRRETINICO ACID.
MX2021012629A (en) * 2021-10-14 2023-04-17 Maria Esther Dragustinovis Ruiz Formulation for the management and antiviral, immunomodulatory, and anti-inflammatory treatment of the infection by the sars-cov2 virus (covid-19) and its variants formulated from the salt of glysirisinic acid and the derivates of its chemical structure, as well as antitussive and anthistaminic agents in syrup.

Also Published As

Publication number Publication date
MX2011002098A (en) 2012-08-29

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Legal Events

Date Code Title Description
GB Transfer or assignment

Owner name: DESARROLLOS VPH, S.A. DE C.V.

FG Grant or registration