MX348455B - A novel analgesic peptide resulting from the venom of spider brachypelma verdezy. - Google Patents
A novel analgesic peptide resulting from the venom of spider brachypelma verdezy.Info
- Publication number
- MX348455B MX348455B MX2011010576A MX2011010576A MX348455B MX 348455 B MX348455 B MX 348455B MX 2011010576 A MX2011010576 A MX 2011010576A MX 2011010576 A MX2011010576 A MX 2011010576A MX 348455 B MX348455 B MX 348455B
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- verdezy
- brachypelma
- venom
- spider
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention refers to a novel peptide know as BvTx47 (SEQ ID NO: 1), with analgesic activity, tested on male mice strain CD-1. The peptide comprises 40 amino acids and has a molecular weight of 4559.6 Daltons. Said peptide was isolated and purified from venom of spider Brachypelma verdezy. The peptide may also be obtained by other means such as chemical synthesis or by the recombinant DNA technique for which the invention provides the encoding nucleotide sequence. The peptide BvTx47 (SEQ ID NO: 1) is of a folded beta secondary structure and with disulfide bridges of the direct disulfide hairpin type (DDH), which differs from the structure of further peptides, such as those having an inhibitor cysteine knot structure (ICK).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2011010576A MX348455B (en) | 2011-10-07 | 2011-10-07 | A novel analgesic peptide resulting from the venom of spider brachypelma verdezy. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2011010576A MX348455B (en) | 2011-10-07 | 2011-10-07 | A novel analgesic peptide resulting from the venom of spider brachypelma verdezy. |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2011010576A MX2011010576A (en) | 2013-04-16 |
MX348455B true MX348455B (en) | 2017-06-01 |
Family
ID=48741677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011010576A MX348455B (en) | 2011-10-07 | 2011-10-07 | A novel analgesic peptide resulting from the venom of spider brachypelma verdezy. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX348455B (en) |
-
2011
- 2011-10-07 MX MX2011010576A patent/MX348455B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MX2011010576A (en) | 2013-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |