MX2023012769A - Terapia de linfocitos infiltrantes de tumor. - Google Patents

Terapia de linfocitos infiltrantes de tumor.

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Publication number
MX2023012769A
MX2023012769A MX2023012769A MX2023012769A MX2023012769A MX 2023012769 A MX2023012769 A MX 2023012769A MX 2023012769 A MX2023012769 A MX 2023012769A MX 2023012769 A MX2023012769 A MX 2023012769A MX 2023012769 A MX2023012769 A MX 2023012769A
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MX
Mexico
Prior art keywords
tils
tumor infiltrating
infiltrating lymphocytes
subject
present disclosure
Prior art date
Application number
MX2023012769A
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English (en)
Inventor
Mario Filion
Original Assignee
Alethia Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Alethia Biotherapeutics Inc filed Critical Alethia Biotherapeutics Inc
Publication of MX2023012769A publication Critical patent/MX2023012769A/es

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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Abstract

La presente descripción se relaciona generalmente a un método para tratar el cáncer por administración de linfocitos infiltrantes de tumor autólogo (TILs por sus siglas en inglés) aislados de un sujeto que ha recibido tratamiento anterior con una terapia anticáncer que comprende anticuerpo anticlusterina o fragmento de unión a antígeno de este. El método de la presente descripción comprende administrar la terapia anticáncer al sujeto, aislar los TILs, y reinfusionar los TILs al sujeto. La presente descripción también se relaciona al uso de un anticuerpo anticlusterina o fragmento de unión a antígeno de este en un método in vitro o ex vivo para generar los linfocitos infiltrantes de tumor (TILs).
MX2023012769A 2021-04-27 2022-04-27 Terapia de linfocitos infiltrantes de tumor. MX2023012769A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163180279P 2021-04-27 2021-04-27
PCT/CA2022/050636 WO2022226641A1 (en) 2021-04-27 2022-04-27 Tumor infiltrating lymphocytes therapy

Publications (1)

Publication Number Publication Date
MX2023012769A true MX2023012769A (es) 2023-11-13

Family

ID=83846456

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023012769A MX2023012769A (es) 2021-04-27 2022-04-27 Terapia de linfocitos infiltrantes de tumor.

Country Status (10)

Country Link
US (1) US20240207311A1 (es)
EP (1) EP4329782A1 (es)
JP (1) JP2024516221A (es)
KR (1) KR20240013125A (es)
CN (1) CN117545491A (es)
AU (1) AU2022264619A1 (es)
CA (1) CA3173818A1 (es)
IL (1) IL307962A (es)
MX (1) MX2023012769A (es)
WO (1) WO2022226641A1 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102666585B (zh) * 2009-11-24 2015-02-18 阿莱斯亚生物疗法股份有限公司 抗簇蛋白抗体和抗原结合片段及其减小肿瘤体积的用途

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Publication number Publication date
AU2022264619A9 (en) 2023-12-07
IL307962A (en) 2023-12-01
US20240207311A1 (en) 2024-06-27
CN117545491A (zh) 2024-02-09
EP4329782A1 (en) 2024-03-06
JP2024516221A (ja) 2024-04-12
AU2022264619A1 (en) 2023-11-30
WO2022226641A1 (en) 2022-11-03
KR20240013125A (ko) 2024-01-30
CA3173818A1 (en) 2022-10-27

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