MX2023000628A - Ocular insert containing a glucocorticoid. - Google Patents

Ocular insert containing a glucocorticoid.

Info

Publication number
MX2023000628A
MX2023000628A MX2023000628A MX2023000628A MX2023000628A MX 2023000628 A MX2023000628 A MX 2023000628A MX 2023000628 A MX2023000628 A MX 2023000628A MX 2023000628 A MX2023000628 A MX 2023000628A MX 2023000628 A MX2023000628 A MX 2023000628A
Authority
MX
Mexico
Prior art keywords
glucocorticoid
insert containing
ocular insert
intracanalicular
hydrogel
Prior art date
Application number
MX2023000628A
Other languages
Spanish (es)
Inventor
Michael Goldstein
Charles D Blizzard
Ankita Desai
Original Assignee
Ocular Therapeutix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ocular Therapeutix Inc filed Critical Ocular Therapeutix Inc
Publication of MX2023000628A publication Critical patent/MX2023000628A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Abstract

In certain embodiments, the invention relates to a sustained release biodegradable intracanalicular insert containing a glucocorticoid dispersed in a hydrogel for the treatment of dry eye disease.
MX2023000628A 2020-07-16 2021-07-15 Ocular insert containing a glucocorticoid. MX2023000628A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063052646P 2020-07-16 2020-07-16
US202063124176P 2020-12-11 2020-12-11
US202163181720P 2021-04-29 2021-04-29
PCT/US2021/041761 WO2022015940A1 (en) 2020-07-16 2021-07-15 Ocular insert containing a glucocorticoid

Publications (1)

Publication Number Publication Date
MX2023000628A true MX2023000628A (en) 2023-02-27

Family

ID=77300995

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023000628A MX2023000628A (en) 2020-07-16 2021-07-15 Ocular insert containing a glucocorticoid.

Country Status (10)

Country Link
EP (1) EP4181930A1 (en)
JP (1) JP2023534952A (en)
KR (1) KR20230041708A (en)
CN (1) CN116133664A (en)
AU (1) AU2021309965A1 (en)
BR (1) BR112023000669A2 (en)
CA (1) CA3174217A1 (en)
IL (1) IL299769A (en)
MX (1) MX2023000628A (en)
WO (1) WO2022015940A1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0714391A2 (en) 2006-07-20 2013-04-24 Sicor Inc process for preparing a sterile solid active pharmaceutical ingredient
EP2156823A1 (en) 2008-08-14 2010-02-24 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmeceutical compounds in the form of micro and nanoparticles
CA2750242C (en) * 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
AU2016261925B2 (en) 2015-05-12 2020-10-01 Incept, Llc Drug delivery from hydrogels
BR112019005594A2 (en) * 2016-09-23 2019-08-13 Incept Llc intracameral drug release deposits

Also Published As

Publication number Publication date
AU2021309965A1 (en) 2023-02-23
EP4181930A1 (en) 2023-05-24
CA3174217A1 (en) 2022-01-20
WO2022015940A1 (en) 2022-01-20
BR112023000669A2 (en) 2023-04-25
JP2023534952A (en) 2023-08-15
IL299769A (en) 2023-03-01
KR20230041708A (en) 2023-03-24
CN116133664A (en) 2023-05-16

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