MX2022013927A - Composiciones y metodos para tratar la epilepsia. - Google Patents
Composiciones y metodos para tratar la epilepsia.Info
- Publication number
- MX2022013927A MX2022013927A MX2022013927A MX2022013927A MX2022013927A MX 2022013927 A MX2022013927 A MX 2022013927A MX 2022013927 A MX2022013927 A MX 2022013927A MX 2022013927 A MX2022013927 A MX 2022013927A MX 2022013927 A MX2022013927 A MX 2022013927A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- treating epilepsy
- compositions
- administering
- inhibitor
- Prior art date
Links
- 206010015037 epilepsy Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 230000024203 complement activation Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2857—Seizure disorders; Epilepsy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente descripción se refiere, en términos generales, a métodos para prevenir, reducir el riesgo de desarrollar o tratar la epilepsia, que comprenden administrar a un sujeto un inhibidor de la vía clásica del complemento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063020245P | 2020-05-05 | 2020-05-05 | |
PCT/US2021/030930 WO2021242493A2 (en) | 2020-05-05 | 2021-05-05 | Compositions and methods for treating epilepsy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022013927A true MX2022013927A (es) | 2022-11-30 |
Family
ID=78745740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022013927A MX2022013927A (es) | 2020-05-05 | 2021-05-05 | Composiciones y metodos para tratar la epilepsia. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20240034775A1 (es) |
EP (1) | EP4146276A4 (es) |
JP (1) | JP2023524819A (es) |
CN (1) | CN115996752A (es) |
AU (1) | AU2021278819A1 (es) |
CA (1) | CA3177879A1 (es) |
MX (1) | MX2022013927A (es) |
WO (1) | WO2021242493A2 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY175896A (en) * | 2013-07-09 | 2020-07-14 | Annexon Inc | Anti-complement factor c1q antibodies and uses thereof |
BR112017009297B1 (pt) * | 2014-11-05 | 2024-02-15 | Annexon, Inc | Anticorpos antifator de complemento c1q humanizados, composição farmacêutica e kit compreendendo os mesmos, uso terapêutico destes,polinucleotídeo isolado, célula hospedeira isolada, bem como métodos in vitro para detectar sinapses |
WO2016081643A1 (en) * | 2014-11-19 | 2016-05-26 | Genentech, Inc. | Anti-transferrin receptor antibodies and methods of use |
EP3454901A4 (en) * | 2016-05-09 | 2020-07-29 | Annexon, Inc. | COMPOSITIONS AND METHODS FOR TREATING PROGRESSIVE SPINAL AMYOTROPHY |
AU2017299579A1 (en) * | 2016-07-19 | 2019-01-24 | Annexon, Inc. | Compositions and methods for treating frontotemporal dementia |
-
2021
- 2021-05-05 MX MX2022013927A patent/MX2022013927A/es unknown
- 2021-05-05 AU AU2021278819A patent/AU2021278819A1/en active Pending
- 2021-05-05 CN CN202180032987.3A patent/CN115996752A/zh active Pending
- 2021-05-05 CA CA3177879A patent/CA3177879A1/en active Pending
- 2021-05-05 JP JP2022567591A patent/JP2023524819A/ja active Pending
- 2021-05-05 WO PCT/US2021/030930 patent/WO2021242493A2/en active Application Filing
- 2021-05-05 EP EP21813355.1A patent/EP4146276A4/en active Pending
- 2021-05-05 US US17/923,456 patent/US20240034775A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4146276A2 (en) | 2023-03-15 |
WO2021242493A2 (en) | 2021-12-02 |
CN115996752A (zh) | 2023-04-21 |
JP2023524819A (ja) | 2023-06-13 |
WO2021242493A3 (en) | 2022-06-09 |
US20240034775A1 (en) | 2024-02-01 |
CA3177879A1 (en) | 2021-12-02 |
EP4146276A4 (en) | 2024-08-14 |
AU2021278819A1 (en) | 2022-11-24 |
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