MX2022006422A - Cycloalkyl urea derivative. - Google Patents
Cycloalkyl urea derivative.Info
- Publication number
- MX2022006422A MX2022006422A MX2022006422A MX2022006422A MX2022006422A MX 2022006422 A MX2022006422 A MX 2022006422A MX 2022006422 A MX2022006422 A MX 2022006422A MX 2022006422 A MX2022006422 A MX 2022006422A MX 2022006422 A MX2022006422 A MX 2022006422A
- Authority
- MX
- Mexico
- Prior art keywords
- agent
- urea derivative
- specifically
- invention pertains
- present
- Prior art date
Links
- -1 Cycloalkyl urea derivative Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 abstract 1
- 208000016588 Idiopathic hypersomnia Diseases 0.000 abstract 1
- 102000002512 Orexin Human genes 0.000 abstract 1
- 108050000742 Orexin Receptor Proteins 0.000 abstract 1
- 102000008834 Orexin receptor Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010020765 hypersomnia Diseases 0.000 abstract 1
- 201000003631 narcolepsy Diseases 0.000 abstract 1
- 108060005714 orexin Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000002859 sleep apnea Diseases 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
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- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Abstract
The present invention pertains to a therapeutic agent or preventative agent against diseases involving an orexin receptor, and specifically, an orexin type-2 receptor, said agent containing a novel compound having a urea skeleton or a pharmaceutically acceptable salt thereof as an active ingredient. Specifically, the present invention pertains to a therapeutic agent or preventative agent against diseases such as narcolepsy, idiopathic hypersomnia, hypersomnia, sleep apnea syndrome, and the like.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019213860 | 2019-11-27 | ||
PCT/JP2020/044047 WO2021107023A1 (en) | 2019-11-27 | 2020-11-26 | Cycloalkyl urea derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022006422A true MX2022006422A (en) | 2022-08-25 |
Family
ID=76129521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022006422A MX2022006422A (en) | 2019-11-27 | 2020-11-26 | Cycloalkyl urea derivative. |
Country Status (15)
Country | Link |
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US (1) | US20230088694A1 (en) |
EP (1) | EP4067344A4 (en) |
JP (1) | JPWO2021107023A1 (en) |
KR (1) | KR20220106998A (en) |
CN (1) | CN115003655A (en) |
AU (1) | AU2020394131A1 (en) |
BR (1) | BR112022009861A2 (en) |
CA (1) | CA3157769A1 (en) |
CL (1) | CL2022001389A1 (en) |
CR (1) | CR20220310A (en) |
IL (1) | IL293387A (en) |
MX (1) | MX2022006422A (en) |
PE (1) | PE20221730A1 (en) |
TW (1) | TW202134229A (en) |
WO (1) | WO2021107023A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114014747B (en) * | 2021-08-30 | 2023-12-08 | 海南师范大学 | Polyhydroxy cyclohexene compound and preparation method and application thereof |
WO2023204291A1 (en) * | 2022-04-22 | 2023-10-26 | 住友ファーマ株式会社 | Bicycloamine carboxamide derivative |
WO2024075825A1 (en) * | 2022-10-07 | 2024-04-11 | キッセイ薬品工業株式会社 | Cyclopentane compound |
WO2024095158A1 (en) | 2022-10-31 | 2024-05-10 | Takeda Pharmaceutical Company Limited | Dosing of orexin type 2 receptor agonists |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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RS50756B (en) * | 2004-04-28 | 2010-08-31 | Takeda Pharmaceutical Company Limited | Fused quinoline derivative and use thereof |
CA2598956A1 (en) * | 2005-02-24 | 2006-08-31 | Pfizer Products Inc. | Bicyclic heteroaromatic derivatives useful as anticancer agents |
JP2010155827A (en) * | 2008-12-04 | 2010-07-15 | Takeda Chem Ind Ltd | Spiro-ring compound |
CA2808435C (en) * | 2010-08-10 | 2017-05-09 | Astellas Pharma Inc. | Heterocyclic compound |
GB201318222D0 (en) * | 2013-10-15 | 2013-11-27 | Takeda Pharmaceutical | Novel compounds |
AR102361A1 (en) * | 2014-10-29 | 2017-02-22 | Lilly Co Eli | METHYL-QUINOLINE COMPOUNDS USEFUL TO INHIBIT THE MICROSOMAL PROSTAGLANDIN E2 SYNTHESA-1 |
EP3029024A1 (en) * | 2014-12-02 | 2016-06-08 | Ferrer Internacional, S.A. | 2-(2-aminophenoxy)-3-chloronaphthalene-1,4-dione compounds having orexin 2 receptor agonist activity |
ES2907373T3 (en) | 2016-02-04 | 2022-04-25 | Takeda Pharmaceuticals Co | Substituted piperidine compound and use thereof |
JP6574918B1 (en) * | 2017-08-03 | 2019-09-11 | 武田薬品工業株式会社 | Heterocyclic compounds and uses thereof |
-
2020
- 2020-11-26 MX MX2022006422A patent/MX2022006422A/en unknown
- 2020-11-26 CN CN202080094640.7A patent/CN115003655A/en active Pending
- 2020-11-26 EP EP20893716.9A patent/EP4067344A4/en active Pending
- 2020-11-26 CA CA3157769A patent/CA3157769A1/en active Pending
- 2020-11-26 AU AU2020394131A patent/AU2020394131A1/en active Pending
- 2020-11-26 JP JP2021561498A patent/JPWO2021107023A1/ja active Pending
- 2020-11-26 US US17/610,291 patent/US20230088694A1/en active Pending
- 2020-11-26 PE PE2022000857A patent/PE20221730A1/en unknown
- 2020-11-26 KR KR1020227021008A patent/KR20220106998A/en unknown
- 2020-11-26 BR BR112022009861A patent/BR112022009861A2/en unknown
- 2020-11-26 TW TW109141535A patent/TW202134229A/en unknown
- 2020-11-26 IL IL293387A patent/IL293387A/en unknown
- 2020-11-26 WO PCT/JP2020/044047 patent/WO2021107023A1/en active Application Filing
- 2020-11-26 CR CR20220310A patent/CR20220310A/en unknown
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2022
- 2022-05-26 CL CL2022001389A patent/CL2022001389A1/en unknown
Also Published As
Publication number | Publication date |
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CN115003655A (en) | 2022-09-02 |
AU2020394131A1 (en) | 2022-07-14 |
PE20221730A1 (en) | 2022-11-07 |
BR112022009861A2 (en) | 2022-08-02 |
CR20220310A (en) | 2022-09-23 |
EP4067344A1 (en) | 2022-10-05 |
WO2021107023A1 (en) | 2021-06-03 |
CL2022001389A1 (en) | 2023-03-24 |
JPWO2021107023A1 (en) | 2021-06-03 |
IL293387A (en) | 2022-07-01 |
EP4067344A4 (en) | 2023-12-20 |
TW202134229A (en) | 2021-09-16 |
US20230088694A1 (en) | 2023-03-23 |
CA3157769A1 (en) | 2021-06-03 |
KR20220106998A (en) | 2022-08-01 |
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