MX2022005407A - Treating liver disorders. - Google Patents

Treating liver disorders.

Info

Publication number
MX2022005407A
MX2022005407A MX2022005407A MX2022005407A MX2022005407A MX 2022005407 A MX2022005407 A MX 2022005407A MX 2022005407 A MX2022005407 A MX 2022005407A MX 2022005407 A MX2022005407 A MX 2022005407A MX 2022005407 A MX2022005407 A MX 2022005407A
Authority
MX
Mexico
Prior art keywords
treating liver
liver disorders
disorders
treating
manifestations
Prior art date
Application number
MX2022005407A
Other languages
Spanish (es)
Inventor
Kevin Klucher
Weidong Zhong
Martijn Fenaux
Yujin Wang
Original Assignee
Terns Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terns Pharmaceuticals Inc filed Critical Terns Pharmaceuticals Inc
Publication of MX2022005407A publication Critical patent/MX2022005407A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Provided herein are methods and compositions for treating liver disorders, including without limitation non-alcoholic steatohepatitis, and symptoms and manifestations thereof, in a patient.
MX2022005407A 2019-11-08 2020-11-06 Treating liver disorders. MX2022005407A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962933277P 2019-11-08 2019-11-08
US202063004403P 2020-04-02 2020-04-02
PCT/US2020/059522 WO2021092474A1 (en) 2019-11-08 2020-11-06 Treating liver disorders

Publications (1)

Publication Number Publication Date
MX2022005407A true MX2022005407A (en) 2022-05-24

Family

ID=75849579

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022005407A MX2022005407A (en) 2019-11-08 2020-11-06 Treating liver disorders.

Country Status (11)

Country Link
EP (1) EP4054567A4 (en)
JP (1) JP2023501386A (en)
KR (1) KR20220098168A (en)
CN (1) CN114667142A (en)
AU (1) AU2020380968A1 (en)
BR (1) BR112022008639A2 (en)
CA (1) CA3160445A1 (en)
CL (1) CL2022001167A1 (en)
IL (1) IL292459A (en)
MX (1) MX2022005407A (en)
WO (1) WO2021092474A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230119130A (en) 2020-12-14 2023-08-16 리제너론 파마슈티칼스 인코포레이티드 Methods of Treating Metabolic Disorders and Cardiovascular Disease with Inhibin Subunit Beta E (INHBE) Inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200906823A (en) * 2007-07-16 2009-02-16 Lilly Co Eli Compounds and methods for modulating FXR
US20140187633A1 (en) * 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
CN109152840A (en) * 2016-03-28 2019-01-04 英特塞普特医药品公司 Pass through the drug for combining FXR agonist and ARB to obtain
WO2018170173A1 (en) * 2017-03-15 2018-09-20 Metacrine, Inc. Farnesoid x receptor agonists and uses thereof
WO2019023245A1 (en) * 2017-07-25 2019-01-31 Cedars-Sinai Medical Center Methods for treating liver diseases
CA3110256A1 (en) * 2018-08-30 2020-03-05 Terns Pharmaceuticals, Inc. Treating liver disorders

Also Published As

Publication number Publication date
CA3160445A1 (en) 2021-05-14
EP4054567A1 (en) 2022-09-14
CN114667142A (en) 2022-06-24
JP2023501386A (en) 2023-01-18
AU2020380968A1 (en) 2022-05-12
WO2021092474A1 (en) 2021-05-14
KR20220098168A (en) 2022-07-11
IL292459A (en) 2022-06-01
BR112022008639A2 (en) 2022-07-19
EP4054567A4 (en) 2024-01-10
CL2022001167A1 (en) 2023-02-10

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