MX2022004655A - Analizadores biologicos portatiles configurables para la identificacion de productos biologicos basandose en la espectroscopia raman. - Google Patents

Analizadores biologicos portatiles configurables para la identificacion de productos biologicos basandose en la espectroscopia raman.

Info

Publication number
MX2022004655A
MX2022004655A MX2022004655A MX2022004655A MX2022004655A MX 2022004655 A MX2022004655 A MX 2022004655A MX 2022004655 A MX2022004655 A MX 2022004655A MX 2022004655 A MX2022004655 A MX 2022004655A MX 2022004655 A MX2022004655 A MX 2022004655A
Authority
MX
Mexico
Prior art keywords
biological
classification model
raman
analyzers
configurable handheld
Prior art date
Application number
MX2022004655A
Other languages
English (en)
Inventor
Robert Soto
David Meriage
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2022004655A publication Critical patent/MX2022004655A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65Raman scattering
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0264Electrical interface; User interface
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02Details
    • G01J3/0272Handheld
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/02Mechanical
    • G01N2201/022Casings
    • G01N2201/0221Portable; cableless; compact; hand-held
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/129Using chemometrical methods

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Se describen analizadores biológicos portátiles configurables y métodos analíticos biológicos relacionados para la identificación de productos biológicos basándose en la espectroscopia Raman. Se carga una configuración de modelo de clasificación biológica en una memoria informática de un analizador biológico portátil configurable que tiene un procesador y un dispositivo de exploración. La configuración de modelo de clasificación biológica incluye un modelo de clasificación biológica configurado para recibir un conjunto de datos espectrales basado en Raman que define una muestra de producto biológico explorada por el dispositivo de exploración. Se ejecuta un algoritmo de preprocesamiento espectral para reducir una variación espectral del conjunto de datos espectrales basado en Raman. El modelo de clasificación biológica identifica un tipo de producto biológico basándose en el conjunto de datos espectrales basado en Raman y, además basándose en un componente de clasificación seleccionado para reducir al menos uno de entre (1) un error residual Q o (2) un valor de resumen de ajuste del modelo de clasificación biológica. La configuración de modelo de clasificación biológica se puede transferir a y cargar en otros analizadores biológicos portátiles configurables.
MX2022004655A 2019-10-25 2020-10-23 Analizadores biologicos portatiles configurables para la identificacion de productos biologicos basandose en la espectroscopia raman. MX2022004655A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962925893P 2019-10-25 2019-10-25
US202063043976P 2020-06-25 2020-06-25
PCT/US2020/056961 WO2021081263A1 (en) 2019-10-25 2020-10-23 Configurable handheld biological analyzers for identification of biological products based on raman spectroscopy

Publications (1)

Publication Number Publication Date
MX2022004655A true MX2022004655A (es) 2022-05-25

Family

ID=75620833

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004655A MX2022004655A (es) 2019-10-25 2020-10-23 Analizadores biologicos portatiles configurables para la identificacion de productos biologicos basandose en la espectroscopia raman.

Country Status (13)

Country Link
US (1) US20220390375A1 (es)
EP (1) EP4048988A4 (es)
JP (1) JP2022552876A (es)
KR (1) KR20220084321A (es)
CN (1) CN114599944A (es)
AU (1) AU2020372414A1 (es)
BR (1) BR112022007687A2 (es)
CA (1) CA3158520A1 (es)
CL (1) CL2022001017A1 (es)
IL (1) IL291455A (es)
MX (1) MX2022004655A (es)
TW (1) TW202124922A (es)
WO (1) WO2021081263A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114295601B (zh) * 2021-12-31 2024-01-30 厦门大学 一种基于连续体束缚态的表面拉曼增强传感结构
WO2024129650A1 (en) * 2022-12-12 2024-06-20 Genentech, Inc. Real-time automated monitoring and control of ultrafiltration/diafiltration (uf/df) conditioning and dilution processes

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7194369B2 (en) * 2001-07-23 2007-03-20 Cognis Corporation On-site analysis system with central processor and method of analyzing
US7688440B2 (en) * 2005-01-27 2010-03-30 Prescient Medical, Inc. Raman spectroscopic test strip systems
US7420663B2 (en) * 2005-05-24 2008-09-02 Bwt Property Inc. Spectroscopic sensor on mobile phone
US7525102B1 (en) * 2005-10-03 2009-04-28 Sparta, Inc. Agent detection in the presence of background clutter
US8330122B2 (en) * 2007-11-30 2012-12-11 Honeywell International Inc Authenticatable mark, systems for preparing and authenticating the mark
GB2466442A (en) * 2008-12-18 2010-06-23 Dublin Inst Of Technology A system to analyze a sample on a slide using Raman spectroscopy on an identified area of interest
CA2786740A1 (en) * 2010-01-22 2011-07-28 British Columbia Cancer Agency Branch Apparatus and methods for characterization of lung tissue by raman spectroscopy
US9662047B2 (en) * 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
JP6012614B2 (ja) * 2010-11-05 2016-10-25 フリーダム メディテック インコーポレイテッド 生体組織の構造的性質に影響する疾患を非侵襲的に検出するための装置および方法
US9752935B2 (en) * 2014-08-29 2017-09-05 Marqmetrix, Inc. Portable analytical equipment
EP3207499A4 (en) * 2014-10-17 2018-09-19 Cireca Theranostics, LLC Methods and systems for classifying biological samples, including optimization of analyses and use of correlation
CN104764734A (zh) * 2015-04-30 2015-07-08 江苏易谱恒科技有限公司 基于拉曼光谱和svm算法的果汁香精香料的鉴别方法
US10365229B2 (en) * 2015-12-31 2019-07-30 Kaiser Optical Systems, Inc. Real-time characterization of pharmaceutical tablet coatings using Raman spectroscopy
CA3018039C (en) * 2016-03-24 2023-08-29 Harman International Industries, Incorporated Signal quality-based enhancement and compensation of compressed audio signals
US10254215B2 (en) * 2016-04-07 2019-04-09 Verifood, Ltd. Spectrometry system applications

Also Published As

Publication number Publication date
CN114599944A (zh) 2022-06-07
CA3158520A1 (en) 2021-04-29
EP4048988A1 (en) 2022-08-31
BR112022007687A2 (pt) 2022-07-12
JP2022552876A (ja) 2022-12-20
WO2021081263A1 (en) 2021-04-29
KR20220084321A (ko) 2022-06-21
CL2022001017A1 (es) 2023-02-03
AU2020372414A1 (en) 2022-04-07
TW202124922A (zh) 2021-07-01
IL291455A (en) 2022-05-01
EP4048988A4 (en) 2023-12-06
US20220390375A1 (en) 2022-12-08

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