MX2021012313A - Formas cristalinas de un inhibidor de trpc de piridazinona. - Google Patents
Formas cristalinas de un inhibidor de trpc de piridazinona.Info
- Publication number
- MX2021012313A MX2021012313A MX2021012313A MX2021012313A MX2021012313A MX 2021012313 A MX2021012313 A MX 2021012313A MX 2021012313 A MX2021012313 A MX 2021012313A MX 2021012313 A MX2021012313 A MX 2021012313A MX 2021012313 A MX2021012313 A MX 2021012313A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitor
- trpc
- pyridazinone
- crystal forms
- compound
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004310 Ion Channels Human genes 0.000 abstract 1
- 101100100680 Schizosaccharomyces pombe (strain 972 / ATCC 24843) trp4 gene Proteins 0.000 abstract 1
- 102000003627 TRPC1 Human genes 0.000 abstract 1
- 101150017559 TRPC1 gene Proteins 0.000 abstract 1
- 102000003622 TRPC4 Human genes 0.000 abstract 1
- 102000003621 TRPC5 Human genes 0.000 abstract 1
- 101150042815 TRPC5 gene Proteins 0.000 abstract 1
- 101150099990 Trpc4 gene Proteins 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2019/081985 WO2020206623A1 (en) | 2019-04-10 | 2019-04-10 | Crystal forms |
| PCT/US2020/027689 WO2020210639A1 (en) | 2019-04-10 | 2020-04-10 | Crystal forms of a pyridazinone trpc inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021012313A true MX2021012313A (es) | 2021-11-17 |
Family
ID=70482847
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021012313A MX2021012313A (es) | 2019-04-10 | 2020-04-10 | Formas cristalinas de un inhibidor de trpc de piridazinona. |
| MX2025006384A MX2025006384A (es) | 2019-04-10 | 2021-10-07 | Formas cristalinas de un inhibidor de trpc de piridazinona |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2025006384A MX2025006384A (es) | 2019-04-10 | 2021-10-07 | Formas cristalinas de un inhibidor de trpc de piridazinona |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12655132B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3953352A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7738482B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN114502552B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2020272030C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112021018221A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3136652A1 (cg-RX-API-DMAC7.html) |
| MA (1) | MA55614A (cg-RX-API-DMAC7.html) |
| MX (2) | MX2021012313A (cg-RX-API-DMAC7.html) |
| WO (2) | WO2020206623A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12435078B2 (en) | 2017-09-18 | 2025-10-07 | Gfb (Abc), Llc | Pyridazinones and methods of use thereof |
| LT3852533T (lt) * | 2018-09-18 | 2024-06-10 | Gfb (Abc), Llc | Piridazinonai ir jų naudojimo būdai |
| WO2020206623A1 (en) | 2019-04-10 | 2020-10-15 | Goldfinch Bio, Inc. | Crystal forms |
| CA3136632A1 (en) | 2019-04-11 | 2020-10-15 | Goldfinch Bio, Inc. | Spray-dried formulation of a pyridazinone trpc5 inhibitor |
| AU2020357178A1 (en) * | 2019-10-04 | 2022-05-12 | Gfb (Abc), Llc | Biomarker-based treatment of focal segmental glomerulosclerosis and diabetic kidney disease |
| KR102873922B1 (ko) | 2020-07-03 | 2025-10-20 | 우한 크리에이터나 사이언스 앤드 테크놀로지 컴퍼니, 리미티드 | 헤테로고리 화합물 및 이의 용도 |
| JP7701559B2 (ja) * | 2021-09-10 | 2025-07-01 | メッドシャイン ディスカバリー インコーポレイテッド | ハロゲン置換のピリダジノン系化合物及びその使用 |
| EP4470540A4 (en) * | 2022-01-27 | 2025-06-11 | Wuhan Createrna Science and Technology Co.,Ltd. | USE OF A HETEROCYCLIC COMPOUND |
| CN119546303A (zh) * | 2022-08-05 | 2025-02-28 | 武汉朗来科技发展有限公司 | 包含杂环化合物的药物组合物及其制备方法和应用 |
| WO2025250920A1 (en) | 2024-05-31 | 2025-12-04 | Gfb (Abc), Llc | Pyridazinone phosphate compounds, pharmaceutical compositions, and medical uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP310798A0 (en) * | 1998-04-22 | 1998-05-14 | Soltec Research Pty Ltd | Vehicle system for a composition comprising a piperidinopyrimidine derivative |
| US8633233B2 (en) * | 2008-08-06 | 2014-01-21 | Hydra Biosciences, Inc. | Methods and compositions for treating anxiety |
| EP3180340B1 (en) * | 2014-08-11 | 2018-10-10 | Hydra Biosciences, Inc. | Pyrido[2,3-d]pyrimidine-2,4(1h,3h)-dione derivatives |
| US12435078B2 (en) * | 2017-09-18 | 2025-10-07 | Gfb (Abc), Llc | Pyridazinones and methods of use thereof |
| LT3852533T (lt) | 2018-09-18 | 2024-06-10 | Gfb (Abc), Llc | Piridazinonai ir jų naudojimo būdai |
| WO2020206623A1 (en) | 2019-04-10 | 2020-10-15 | Goldfinch Bio, Inc. | Crystal forms |
| KR102873922B1 (ko) | 2020-07-03 | 2025-10-20 | 우한 크리에이터나 사이언스 앤드 테크놀로지 컴퍼니, 리미티드 | 헤테로고리 화합물 및 이의 용도 |
-
2019
- 2019-04-10 WO PCT/CN2019/081985 patent/WO2020206623A1/en not_active Ceased
-
2020
- 2020-04-10 MX MX2021012313A patent/MX2021012313A/es unknown
- 2020-04-10 CN CN202080042302.9A patent/CN114502552B/zh active Active
- 2020-04-10 CN CN202411019840.2A patent/CN119264134A/zh active Pending
- 2020-04-10 WO PCT/US2020/027689 patent/WO2020210639A1/en not_active Ceased
- 2020-04-10 US US17/603,249 patent/US12655132B2/en active Active
- 2020-04-10 MA MA055614A patent/MA55614A/fr unknown
- 2020-04-10 AU AU2020272030A patent/AU2020272030C1/en active Active
- 2020-04-10 CA CA3136652A patent/CA3136652A1/en active Pending
- 2020-04-10 JP JP2021555545A patent/JP7738482B2/ja active Active
- 2020-04-10 BR BR112021018221A patent/BR112021018221A2/pt unknown
- 2020-04-10 EP EP20723672.0A patent/EP3953352A1/en active Pending
-
2021
- 2021-10-07 MX MX2025006384A patent/MX2025006384A/es unknown
-
2025
- 2025-09-01 JP JP2025144862A patent/JP2026004294A/ja active Pending
-
2026
- 2026-02-11 AU AU2026201003A patent/AU2026201003A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7738482B2 (ja) | 2025-09-12 |
| EP3953352A1 (en) | 2022-02-16 |
| CA3136652A1 (en) | 2020-10-15 |
| WO2020206623A1 (en) | 2020-10-15 |
| BR112021018221A2 (pt) | 2022-01-18 |
| JP2022525759A (ja) | 2022-05-19 |
| MA55614A (fr) | 2022-02-16 |
| JP2026004294A (ja) | 2026-01-14 |
| MX2025006384A (es) | 2025-07-01 |
| AU2020272030C1 (en) | 2026-05-07 |
| US20220177455A1 (en) | 2022-06-09 |
| AU2020272030B2 (en) | 2025-11-13 |
| WO2020210639A1 (en) | 2020-10-15 |
| AU2026201003A1 (en) | 2026-03-05 |
| CN114502552A (zh) | 2022-05-13 |
| AU2020272030A1 (en) | 2021-11-11 |
| CN119264134A (zh) | 2025-01-07 |
| US12655132B2 (en) | 2026-06-16 |
| CN114502552B (zh) | 2024-08-16 |
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