MX2021005016A - Apparatus and process to chemically crosslink in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics. - Google Patents
Apparatus and process to chemically crosslink in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics.Info
- Publication number
- MX2021005016A MX2021005016A MX2021005016A MX2021005016A MX2021005016A MX 2021005016 A MX2021005016 A MX 2021005016A MX 2021005016 A MX2021005016 A MX 2021005016A MX 2021005016 A MX2021005016 A MX 2021005016A MX 2021005016 A MX2021005016 A MX 2021005016A
- Authority
- MX
- Mexico
- Prior art keywords
- human collagen
- chemical
- controlled
- biological characteristics
- structure made
- Prior art date
Links
- 102000008186 Collagen Human genes 0.000 title abstract 4
- 108010035532 Collagen Proteins 0.000 title abstract 4
- 229920001436 collagen Polymers 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 238000004132 cross linking Methods 0.000 abstract 2
- 239000007789 gas Substances 0.000 abstract 2
- 238000007789 sealing Methods 0.000 abstract 2
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 238000000859 sublimation Methods 0.000 abstract 1
- 230000008022 sublimation Effects 0.000 abstract 1
- 238000009423 ventilation Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
- B01J3/03—Pressure vessels, or vacuum vessels, having closure members or seals specially adapted therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials For Medical Uses (AREA)
Abstract
The present invention relates to an apparatus and process for chemically crosslinking in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics. It comprises a crosslinking chamber with a tight sealing lid integrating a vacuum gauge for its measurement, configured to house a support structure with the collagen arranged and placed. Said chamber is connected to a sublimation chamber through an interconnection duct with flow control, including a plunger attached to a rod that passes through a tight sealing lid configured to accommodate a quantity of powdered paraformaldehyde. Also, it contains a vacuum-generating duct with vacuum regulation, injecting medical air with flow control means for ventilation and gas expulsion towards an extraction hood of gases, once crosslinked human collagen.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2021005016A MX2021005016A (en) | 2021-04-29 | 2021-04-29 | Apparatus and process to chemically crosslink in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics. |
PCT/MX2021/050070 WO2022231417A1 (en) | 2021-04-29 | 2021-10-28 | Apparatus and process for the controlled and precise chemical cross-linking of a structure made of human collagen having variable mechanical, chemical and biological features |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2021005016A MX2021005016A (en) | 2021-04-29 | 2021-04-29 | Apparatus and process to chemically crosslink in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021005016A true MX2021005016A (en) | 2022-10-31 |
Family
ID=83847164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021005016A MX2021005016A (en) | 2021-04-29 | 2021-04-29 | Apparatus and process to chemically crosslink in a controlled and precise manner a structure made of human collagen with variable mechanical, chemical, and biological characteristics. |
Country Status (2)
Country | Link |
---|---|
MX (1) | MX2021005016A (en) |
WO (1) | WO2022231417A1 (en) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5147514A (en) * | 1987-08-02 | 1992-09-15 | University Of North Carolina | Process for cross-linking collagenous material and resulting product |
TWI230619B (en) * | 2001-08-16 | 2005-04-11 | Ind Tech Res Inst | Method of crosslinking of porous biodegradable polymers |
WO2006029571A1 (en) * | 2004-09-14 | 2006-03-23 | The University Of Hong Kong | Photochemically crosslinked collagen scaffolds and methods for their preparation |
-
2021
- 2021-04-29 MX MX2021005016A patent/MX2021005016A/en unknown
- 2021-10-28 WO PCT/MX2021/050070 patent/WO2022231417A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2022231417A1 (en) | 2022-11-03 |
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