Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunogen IncfiledCriticalImmunogen Inc
Priority to MX2021000215ApriorityCriticalpatent/MX2021000215A/en
Publication of MX2021000215ApublicationCriticalpatent/MX2021000215A/en
Measuring Or Testing Involving Enzymes Or Micro-Organisms
(AREA)
Investigating Or Analysing Biological Materials
(AREA)
Abstract
The invention generally relates to antibodies that bind to human folate receptor 1 and diagnostic assays for folate receptor 1 -based therapies. Methods of using the antibodies to monitor therapy are further provided. The present invention provides methods for detection of FOLRI in a sample and can be used, for example, to stratify patients. Thus, in one embodiment, the invention provides a method of treating a patient having a folate receptor 1 -mediated disease comprising: (a) measuring the shed folate receptor 1 (FOLRI) expression level or FOLR1 on a circuiting tumor cell (CTC) in a sample taken from a patient.
MX2021000215A2021-01-072021-01-07Diagnostic assays and kits for detection of folate receptor 1.
MX2021000215A
(en)
Estimating clinically meaningful changes for the Functional Assessment of Cancer Therapy—Prostate: results from a clinical trial of patients with metastatic hormone-refractory prostate cancer
Association between disease-specific quality of life and magnetic resonance imaging outcomes in a clinical trial of prolotherapy for knee osteoarthritis
Influence of cognitive impairment on the recovery of subjects with subacute stroke undergoing upper limb robotic rehabilitation. Brain Sci. 2021; 11 (5): 587. doi: 10.3390/brainsci11050587.»
Cross-cultural translation and validation of the Hindi version of the intermittent and constant osteoarthritis pain scale in knee osteoarthritis patients
Protocol: Effect of transcutaneous electrical acupoint stimulation on bone metabolism in patients with immobilisation after foot and ankle fracture surgery: a randomised controlled trial study protocol
A critical appraisal of" Acute effect of scapular proprioceptive neuromuscular facilitation (PNF) techniques and classic exercises in adhesive capsulitis: a randomized controlled trial"