MX2019007892A - Compuestos inhibidores de metaloenzimas. - Google Patents
Compuestos inhibidores de metaloenzimas.Info
- Publication number
- MX2019007892A MX2019007892A MX2019007892A MX2019007892A MX2019007892A MX 2019007892 A MX2019007892 A MX 2019007892A MX 2019007892 A MX2019007892 A MX 2019007892A MX 2019007892 A MX2019007892 A MX 2019007892A MX 2019007892 A MX2019007892 A MX 2019007892A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitor compounds
- metalloenzyme inhibitor
- metalloenzyme
- compounds
- metalloenzymes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Se proveen compuestos que tienen actividad moduladora de metaloenzimas y métodos de tratamiento de enfermedades, trastornos o síntomas de los mismos mediados por tales metaloenzimas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662440181P | 2016-12-29 | 2016-12-29 | |
PCT/US2017/068190 WO2018125800A2 (en) | 2016-12-29 | 2017-12-22 | Metalloenzyme inhibitor compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019007892A true MX2019007892A (es) | 2020-02-05 |
Family
ID=62709109
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019007892A MX2019007892A (es) | 2016-12-29 | 2017-12-22 | Compuestos inhibidores de metaloenzimas. |
MX2022012386A MX2022012386A (es) | 2016-12-29 | 2019-06-28 | Compuestos inhibidores de metaloenzimas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022012386A MX2022012386A (es) | 2016-12-29 | 2019-06-28 | Compuestos inhibidores de metaloenzimas. |
Country Status (15)
Country | Link |
---|---|
US (3) | US10085984B2 (es) |
EP (2) | EP3562487B1 (es) |
JP (2) | JP7227157B2 (es) |
KR (1) | KR20190129034A (es) |
CN (1) | CN110691598A (es) |
AU (1) | AU2017387033B2 (es) |
BR (1) | BR112019013478A2 (es) |
CA (1) | CA3055292A1 (es) |
DK (1) | DK3562487T3 (es) |
ES (1) | ES2967119T3 (es) |
FI (1) | FI3562487T3 (es) |
MX (2) | MX2019007892A (es) |
RU (1) | RU2764666C2 (es) |
TW (1) | TWI786078B (es) |
WO (1) | WO2018125800A2 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2774267T3 (es) * | 2012-01-20 | 2020-07-20 | Mycovia Pharmaceuticals Inc | Compuestos inhibidores de metaloenzimas |
WO2018125799A2 (en) | 2016-12-29 | 2018-07-05 | Viamet Pharmaceuticals (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
US20220081420A1 (en) * | 2019-01-08 | 2022-03-17 | Steven Sparks | Metalloenzyme inhibitor compounds |
GB201901757D0 (en) | 2019-02-08 | 2019-03-27 | Syngenta Crop Protection Ag | Herbicidal compounds |
EP4153566A1 (en) | 2020-05-19 | 2023-03-29 | Bayer CropScience Aktiengesellschaft | Azabicyclic(thio)amides as fungicidal compounds |
CA3186659A1 (en) | 2020-06-10 | 2021-12-16 | Bayer Aktiengesellschaft | Azabicyclyl-substituted heterocycles as fungicides |
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US4882150A (en) | 1988-06-03 | 1989-11-21 | Kaufman Herbert E | Drug delivery system |
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US5077033A (en) | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
US5352456A (en) | 1991-10-10 | 1994-10-04 | Cygnus Therapeutic Systems | Device for administering drug transdermally which provides an initial pulse of drug |
JPH07502219A (ja) | 1991-12-18 | 1995-03-09 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 多重層型バリアー構造体 |
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IL114193A (en) | 1994-06-20 | 2000-02-29 | Teva Pharma | Ophthalmic pharmaceutical compositions based on sodium alginate |
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IT1283911B1 (it) | 1996-02-05 | 1998-05-07 | Farmigea Spa | Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo |
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WO2018125799A2 (en) | 2016-12-29 | 2018-07-05 | Viamet Pharmaceuticals (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
-
2017
- 2017-12-22 DK DK17887556.3T patent/DK3562487T3/da active
- 2017-12-22 JP JP2019556790A patent/JP7227157B2/ja active Active
- 2017-12-22 MX MX2019007892A patent/MX2019007892A/es unknown
- 2017-12-22 AU AU2017387033A patent/AU2017387033B2/en active Active
- 2017-12-22 RU RU2019123854A patent/RU2764666C2/ru active
- 2017-12-22 EP EP17887556.3A patent/EP3562487B1/en active Active
- 2017-12-22 KR KR1020197022285A patent/KR20190129034A/ko not_active Application Discontinuation
- 2017-12-22 WO PCT/US2017/068190 patent/WO2018125800A2/en unknown
- 2017-12-22 CN CN201780087610.1A patent/CN110691598A/zh active Pending
- 2017-12-22 FI FIEP17887556.3T patent/FI3562487T3/fi active
- 2017-12-22 ES ES17887556T patent/ES2967119T3/es active Active
- 2017-12-22 BR BR112019013478-6A patent/BR112019013478A2/pt active Search and Examination
- 2017-12-22 EP EP23212447.9A patent/EP4311577A3/en active Pending
- 2017-12-22 CA CA3055292A patent/CA3055292A1/en active Pending
- 2017-12-29 TW TW106146533A patent/TWI786078B/zh active
- 2017-12-29 US US15/857,950 patent/US10085984B2/en active Active
-
2018
- 2018-09-07 US US16/124,846 patent/US11040034B2/en active Active
-
2019
- 2019-06-28 MX MX2022012386A patent/MX2022012386A/es unknown
-
2021
- 2021-06-17 US US17/350,726 patent/US20210322409A1/en active Pending
-
2023
- 2023-02-09 JP JP2023018482A patent/JP2023071692A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20210322409A1 (en) | 2021-10-21 |
EP3562487A4 (en) | 2020-08-26 |
RU2764666C2 (ru) | 2022-01-19 |
AU2017387033A1 (en) | 2019-08-15 |
EP4311577A2 (en) | 2024-01-31 |
ES2967119T3 (es) | 2024-04-26 |
AU2017387033B2 (en) | 2024-02-01 |
MX2022012386A (es) | 2022-11-30 |
EP4311577A3 (en) | 2024-04-17 |
EP3562487B1 (en) | 2023-11-29 |
DK3562487T3 (da) | 2024-01-02 |
RU2019123854A3 (es) | 2021-05-12 |
KR20190129034A (ko) | 2019-11-19 |
TWI786078B (zh) | 2022-12-11 |
JP7227157B2 (ja) | 2023-02-21 |
US20190008861A1 (en) | 2019-01-10 |
CN110691598A (zh) | 2020-01-14 |
FI3562487T3 (fi) | 2023-12-14 |
US10085984B2 (en) | 2018-10-02 |
BR112019013478A2 (pt) | 2020-01-07 |
CA3055292A1 (en) | 2018-07-05 |
US20180185362A1 (en) | 2018-07-05 |
WO2018125800A3 (en) | 2018-08-16 |
JP2020510693A (ja) | 2020-04-09 |
EP3562487A2 (en) | 2019-11-06 |
US11040034B2 (en) | 2021-06-22 |
TW201831465A (zh) | 2018-09-01 |
JP2023071692A (ja) | 2023-05-23 |
RU2019123854A (ru) | 2021-02-01 |
WO2018125800A2 (en) | 2018-07-05 |
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