MX2017016438A - Chimeric polypeptide, vaccine against babesiosis, immunization methods, detection methods and kit. - Google Patents

Chimeric polypeptide, vaccine against babesiosis, immunization methods, detection methods and kit.

Info

Publication number
MX2017016438A
MX2017016438A MX2017016438A MX2017016438A MX2017016438A MX 2017016438 A MX2017016438 A MX 2017016438A MX 2017016438 A MX2017016438 A MX 2017016438A MX 2017016438 A MX2017016438 A MX 2017016438A MX 2017016438 A MX2017016438 A MX 2017016438A
Authority
MX
Mexico
Prior art keywords
methods
chimeric polypeptide
vaccine against
kit
immunization
Prior art date
Application number
MX2017016438A
Other languages
Spanish (es)
Inventor
Elizabeth Wilkowsky Silvina
Manuel Jaramillo Ortiz José
Paula Del Medico Zajac Maria
Calamante Gabriela
Original Assignee
Instituto Nac De Tecnologia Agropecuaria
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Nac De Tecnologia Agropecuaria filed Critical Instituto Nac De Tecnologia Agropecuaria
Publication of MX2017016438A publication Critical patent/MX2017016438A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • A61K39/018Babesia antigens, e.g. Theileria antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Abstract

A chimeric polypeptide containing a fragment of MSA-2c antigen bound to a fragment of RAP-1 antigen bound to a fragment of HSP20 antigen, where the antigens are antigens of a Babesia genus parasite. For example, the chimeric polypeptide may be represented by an amino acid sequence which contains at least 89% identity in relation to SEQ ID N° 1. It shows a composition for a vaccine against babesiosis, immunization methods and detection methods.
MX2017016438A 2015-06-22 2016-06-22 Chimeric polypeptide, vaccine against babesiosis, immunization methods, detection methods and kit. MX2017016438A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ARP150101988A AR100931A1 (en) 2015-06-22 2015-06-22 CHEMICAL POLIPEPTIDE, VACCINE AGAINST BABESIOSIS, IMMUNIZATION METHODS, DETECTION METHODS AND KIT
PCT/US2016/038611 WO2016209859A1 (en) 2015-06-22 2016-06-22 Chimeric polypeptide, vaccine against babesiosis, immunization methods, detection methods and kit

Publications (1)

Publication Number Publication Date
MX2017016438A true MX2017016438A (en) 2018-08-15

Family

ID=57585545

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017016438A MX2017016438A (en) 2015-06-22 2016-06-22 Chimeric polypeptide, vaccine against babesiosis, immunization methods, detection methods and kit.

Country Status (5)

Country Link
AR (1) AR100931A1 (en)
BR (1) BR112017027804A2 (en)
CO (1) CO2018000255A2 (en)
MX (1) MX2017016438A (en)
WO (1) WO2016209859A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10760137B2 (en) * 2017-07-18 2020-09-01 Roche Molecular Systems, Inc. Compositions and methods for detection of Babesia
CN113740529B (en) * 2021-08-25 2023-05-26 华中农业大学 Babesia canis antibody latex agglutination detection kit and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8710009B2 (en) * 2004-05-26 2014-04-29 The Texas A&M University System HSP20 inhibits amyloidogenesis and neurotoxicity
RU2599544C2 (en) * 2010-12-29 2016-10-10 Интервет Интернэшнл Б.В. Canine babesiosis vaccine antigen

Also Published As

Publication number Publication date
CO2018000255A2 (en) 2018-04-19
AR100931A1 (en) 2016-11-09
BR112017027804A2 (en) 2018-08-28
WO2016209859A1 (en) 2016-12-29

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