MX2017004324A - Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states. - Google Patents
Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states.Info
- Publication number
- MX2017004324A MX2017004324A MX2017004324A MX2017004324A MX2017004324A MX 2017004324 A MX2017004324 A MX 2017004324A MX 2017004324 A MX2017004324 A MX 2017004324A MX 2017004324 A MX2017004324 A MX 2017004324A MX 2017004324 A MX2017004324 A MX 2017004324A
- Authority
- MX
- Mexico
- Prior art keywords
- fatty acid
- disease
- compositions
- omega
- acid ester
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect. The compositions are useful for treating certain disease states which may include (1) malabsorption syndromes, (2) primary sclerosing cholangitis (PSC), (3) non-alcoholic fatty liver disease (NAFLD), (4) sickle cell disease (SCD), (5) age-related macular degeneration (AMD), and (6) neurodegenerative disease, including, Parkinson's Disease (PD), Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Epilepsy, Bi-polar Syndrome, traumatic brain injury, peripheral neuropathy, and Multiple Sclerosis (MS). Described are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions for their administration.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462062638P | 2014-10-10 | 2014-10-10 | |
US201462062634P | 2014-10-10 | 2014-10-10 | |
US201462062646P | 2014-10-10 | 2014-10-10 | |
US201462062651P | 2014-10-10 | 2014-10-10 | |
US201462062643P | 2014-10-10 | 2014-10-10 | |
US201462062652P | 2014-10-10 | 2014-10-10 | |
PCT/US2015/054933 WO2016057915A1 (en) | 2014-10-10 | 2015-10-09 | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017004324A true MX2017004324A (en) | 2017-07-04 |
Family
ID=54347886
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017004324A MX2017004324A (en) | 2014-10-10 | 2015-10-09 | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states. |
MX2020002238A MX2020002238A (en) | 2014-10-10 | 2017-04-03 | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020002238A MX2020002238A (en) | 2014-10-10 | 2017-04-03 | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP3212236A1 (en) |
BR (1) | BR112017007428A2 (en) |
CA (1) | CA2963952C (en) |
CL (1) | CL2017000867A1 (en) |
MA (1) | MA40846A (en) |
MX (2) | MX2017004324A (en) |
WO (1) | WO2016057915A1 (en) |
ZA (1) | ZA201702385B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106692973A (en) * | 2015-11-13 | 2017-05-24 | 深圳君圣泰生物技术有限公司 | Pharmaceutical compositions and applications thereof, and pharmaceutical preparation |
EP3456328A4 (en) * | 2016-05-10 | 2020-02-26 | Shenzhen Hightide Biopharmaceutical., Ltd. | Composition, and application and pharmaceutical preparation thereof |
US11241408B2 (en) | 2016-08-12 | 2022-02-08 | Pharmako Biotechnologies Pty Limited | Omega-3 compositions and methods relating thereto |
FR3092968B1 (en) * | 2019-02-22 | 2021-05-21 | Microphyt | DIETARY SUPPLEMENT |
IT201900007202A1 (en) * | 2019-05-24 | 2020-11-24 | Pavia Farm S R L | COMPOSITION BASED ON LIPOSOLUBLE VITAMINS WITH HIGH ENTERIC ABSORPTION |
WO2021028737A1 (en) | 2019-08-13 | 2021-02-18 | Team Foods Colombia S.A. | Lipid composition comprising antioxidants and natural polyphenols as a non-pharmacological alternative for the treatment and prevention of non-alcoholic fatty liver disease (nafld) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5313343B2 (en) * | 2009-05-22 | 2013-10-09 | 持田製薬株式会社 | Self-emulsifying composition of ω3 fatty acid |
WO2012032414A2 (en) * | 2010-09-08 | 2012-03-15 | Pronova Biopharma Norge As | Compositions comprising a fatty acid oil mixture, a surfactant, and a statin |
EP2793867B1 (en) * | 2011-12-22 | 2021-01-20 | Baes, Erik | Gelatin/alginate delayed release capsules comprising omega-3 fatty acids, and methods and uses thereof |
WO2013148136A1 (en) * | 2012-03-30 | 2013-10-03 | Sancilio & Company, Inc. | Omega-3 fatty acid ester compositions |
-
2015
- 2015-10-08 MA MA040846A patent/MA40846A/en unknown
- 2015-10-09 WO PCT/US2015/054933 patent/WO2016057915A1/en active Application Filing
- 2015-10-09 CA CA2963952A patent/CA2963952C/en active Active
- 2015-10-09 BR BR112017007428A patent/BR112017007428A2/en not_active Application Discontinuation
- 2015-10-09 MX MX2017004324A patent/MX2017004324A/en unknown
- 2015-10-09 EP EP15784877.1A patent/EP3212236A1/en active Pending
-
2017
- 2017-04-03 MX MX2020002238A patent/MX2020002238A/en unknown
- 2017-04-04 ZA ZA2017/02385A patent/ZA201702385B/en unknown
- 2017-04-10 CL CL2017000867A patent/CL2017000867A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA40846A (en) | 2017-09-05 |
CL2017000867A1 (en) | 2017-11-03 |
EP3212236A1 (en) | 2017-09-06 |
MX2020002238A (en) | 2020-07-13 |
ZA201702385B (en) | 2020-12-23 |
CA2963952A1 (en) | 2016-04-14 |
WO2016057915A1 (en) | 2016-04-14 |
BR112017007428A2 (en) | 2017-12-19 |
CA2963952C (en) | 2023-10-17 |
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