MX2015012416A - Heterocyclic compounds and their uses. - Google Patents

Heterocyclic compounds and their uses.

Info

Publication number
MX2015012416A
MX2015012416A MX2015012416A MX2015012416A MX2015012416A MX 2015012416 A MX2015012416 A MX 2015012416A MX 2015012416 A MX2015012416 A MX 2015012416A MX 2015012416 A MX2015012416 A MX 2015012416A MX 2015012416 A MX2015012416 A MX 2015012416A
Authority
MX
Mexico
Prior art keywords
heterocyclic compounds
preparation
methods
pharmaceutical formulations
certain pharmaceutical
Prior art date
Application number
MX2015012416A
Other languages
Spanish (es)
Inventor
Brett Caldwell
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2015012416A publication Critical patent/MX2015012416A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

Provided are certain pharmaceutical formulations of omecamtiv mecarbil and methods for their preparation and use.
MX2015012416A 2013-03-14 2014-03-14 Heterocyclic compounds and their uses. MX2015012416A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361785492P 2013-03-14 2013-03-14
PCT/US2014/027061 WO2014152198A1 (en) 2013-03-14 2014-03-14 Heterocyclic compounds and their uses

Publications (1)

Publication Number Publication Date
MX2015012416A true MX2015012416A (en) 2016-04-07

Family

ID=50439524

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015012416A MX2015012416A (en) 2013-03-14 2014-03-14 Heterocyclic compounds and their uses.

Country Status (9)

Country Link
US (1) US9895308B2 (en)
EP (1) EP2968180B1 (en)
JP (2) JP6634368B2 (en)
AU (1) AU2014240104B2 (en)
CA (1) CA2902424A1 (en)
ES (1) ES2733340T3 (en)
HK (1) HK1220363A1 (en)
MX (1) MX2015012416A (en)
WO (1) WO2014152198A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2902646C (en) 2013-03-14 2022-08-16 Cytokinetics, Inc. Heterocyclic compounds and their uses
WO2019006235A1 (en) * 2017-06-30 2019-01-03 Amgen Inc. Methods of treating heart failure with cardiac sarcomere activators
JP7181896B2 (en) 2017-06-30 2022-12-01 アムジエン・インコーポレーテツド Synthesis of omecamtive mecarbir
BR112020004800A2 (en) 2017-09-13 2020-09-24 Amgen Inc. saramere-activating bisamide compounds and their uses
MA53226A (en) 2018-08-17 2021-11-24 Amgen Inc SALT AND CRYSTALLINE FORMS OF OMECAMTIV MECARBIL
CN114929671B (en) * 2020-01-03 2024-04-16 苏州科睿思制药有限公司 Eutectic of compound I dihydrochloride and preparation method and application thereof
CN115279349A (en) * 2020-02-10 2022-11-01 安进股份有限公司 Oretatocamicobiol tablet
US11702380B2 (en) 2021-03-10 2023-07-18 Amgen Inc. Synthesis of omecamtiv mecarbil

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612059A (en) 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
SI1242055T1 (en) * 1999-12-23 2008-08-31 Pfizer Prod Inc Hydrogel-driven drug dosage form
US8197846B2 (en) * 2003-11-10 2012-06-12 Astellas Pharma Inc. Sustained release pharmaceutical composition
RU2410384C2 (en) 2004-06-17 2011-01-27 Цитокинетикс, Инк. Compounds, compositions and methods of their application
ES2419007T3 (en) * 2005-12-15 2013-08-19 Cytokinetics, Inc. Certain chemical entities, compositions and procedures

Also Published As

Publication number Publication date
US20160015628A1 (en) 2016-01-21
EP2968180A1 (en) 2016-01-20
WO2014152198A1 (en) 2014-09-25
EP2968180B1 (en) 2019-04-24
AU2014240104B2 (en) 2018-11-08
HK1220363A1 (en) 2017-05-05
JP2019048830A (en) 2019-03-28
JP2016513678A (en) 2016-05-16
AU2014240104A1 (en) 2015-09-10
CA2902424A1 (en) 2014-09-25
US9895308B2 (en) 2018-02-20
JP6634368B2 (en) 2020-01-22
ES2733340T3 (en) 2019-11-28

Similar Documents

Publication Publication Date Title
PH12019500176A1 (en) Heterocyclic compounds and ther uses
MX2020005181A (en) Aminopyridine derivatives as tam family kinase inhibitors.
IL240290B (en) Pyridazinone-amides derivatives and pharmaceutical compositions containing them
IL240291B (en) Pyridazinone derivatives and pharmaceutical compositions containing them
IL243608A0 (en) Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
LT2829539T (en) New pyrrole derivatives, method of preparing same and pharmaceutical compositions containing them
IL264259A (en) Oral formulations of pyrrolidine derivatives
MX2015012416A (en) Heterocyclic compounds and their uses.
MX2020001756A (en) Benzoquinolone inhibitors of vmat2.
TN2015000411A1 (en) Ceftolozane antibiotic compositions
EP3038465A4 (en) Oral pharmaceutical formulation of omarigliptin
CL2017000587A1 (en) Tetrahydroquinoline derivatives as bromodomain inhibitors
EP3049389A4 (en) Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
HK1218079A1 (en) Pharmaceutical formulations of nitrite and uses thereof
UY34829A (en) NEW DOSAGE AND FORMULATION
EP3049077A4 (en) Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
PL3143032T3 (en) Novel derivatives of oxazaphosphorines and therapeutic uses thereof
EP2945703A4 (en) Formulations of albu-bche, preparation and uses thereof
EP3052475A4 (en) Pharmaceutical use of 3-benzylsulfonylpropionitrile
TWD173316S (en) Prosthesis
MY180947A (en) Ceftolozane antibiotic compositions

Legal Events

Date Code Title Description
FG Grant or registration