MX2015011499A - Proceso para mejorar la eficacia inhibidora de amilasa a partir de extractos de phaseolus vulgaris. - Google Patents

Proceso para mejorar la eficacia inhibidora de amilasa a partir de extractos de phaseolus vulgaris.

Info

Publication number
MX2015011499A
MX2015011499A MX2015011499A MX2015011499A MX2015011499A MX 2015011499 A MX2015011499 A MX 2015011499A MX 2015011499 A MX2015011499 A MX 2015011499A MX 2015011499 A MX2015011499 A MX 2015011499A MX 2015011499 A MX2015011499 A MX 2015011499A
Authority
MX
Mexico
Prior art keywords
solution
amylase
enhancing
bean extract
phaseolus vulgaris
Prior art date
Application number
MX2015011499A
Other languages
English (en)
Inventor
Robert J Sarama
Gregory Arcuino
Original Assignee
Sunny Delight Beverages Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunny Delight Beverages Company filed Critical Sunny Delight Beverages Company
Publication of MX2015011499A publication Critical patent/MX2015011499A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2422—Alpha-amylase (3.2.1.1.) from plant source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Se describe un método mejorado para purificar material de alfa-amilasa de extracto de porotos. Los materiales purificados mediante este proceso proporcionan una inhibición de amilasa significativamente mayor que los materiales purificados mediante otros procesos; en este proceso: (a) se suspende material de alfa-amilasa de extracto de porotos en una solución acuosa a un pH de solución de alrededor de 3.0 a alrededor de 3.5; (b) se agrega un conservante a la solución; (c) se calienta la solución desde alrededor de 79°C a alrededor de 91°C durante entre alrededor de 10 y alrededor de 120 segundos; (d) se enfría la solución a una temperatura de entre alrededor de 18 a alrededor de 29°C y se deja asentar, en condiciones estáticas sin agitación, a una temperatura dentro de ese intervalo definido durante entre alrededor de 3 a alrededor de 24 horas para permitir que las partículas de extracto de poroto se sedimenten en la solución; y (e) se separan las partículas del sobrenadante.
MX2015011499A 2013-03-13 2014-03-12 Proceso para mejorar la eficacia inhibidora de amilasa a partir de extractos de phaseolus vulgaris. MX2015011499A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779584P 2013-03-13 2013-03-13
US14/204,622 US9290752B2 (en) 2013-03-13 2014-03-11 Process for enhancing the amylase inhibitory efficacy from phaseolus vulgaris extracts
PCT/US2014/024176 WO2014165030A2 (en) 2013-03-13 2014-03-12 Process for enhancing the amylase inhibitory efficacy from phaseolus vulgaris extracts

Publications (1)

Publication Number Publication Date
MX2015011499A true MX2015011499A (es) 2017-03-27

Family

ID=51528815

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011499A MX2015011499A (es) 2013-03-13 2014-03-12 Proceso para mejorar la eficacia inhibidora de amilasa a partir de extractos de phaseolus vulgaris.

Country Status (10)

Country Link
US (1) US9290752B2 (es)
EP (1) EP2970404A2 (es)
JP (1) JP2016517413A (es)
CN (1) CN105008392A (es)
BR (1) BR112015021588A2 (es)
CA (1) CA2900472A1 (es)
HK (1) HK1216539A1 (es)
MX (1) MX2015011499A (es)
RU (1) RU2015143561A (es)
WO (1) WO2014165030A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11096978B2 (en) * 2018-01-12 2021-08-24 Mellitas Health Foods, LLC Common bean (phaseolus vulgaris) extract with high a-amylase inhibitory activity and low hemagglutinin activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID27153A (id) 1998-05-01 2001-03-08 Lilly Co Eli Senyawa inhibitor spla2 untuk mengobati penyakit
DE60012301D1 (de) 1999-01-22 2004-08-26 Hunza Di Pistolesi Elvira & C Lipoproteinkomplexe und zusammensetzungen, die diese enthalten
AU2003279636A1 (en) * 2002-06-28 2004-01-19 Pharmachem Laboratories, Inc. Purified amylase inhibitor and novel process for obtaining the same
ITMI20040619A1 (it) 2004-03-30 2004-06-30 Consiglio Nazionale Ricerche Estratto purificato di inibitore dell'alfa-amilasi da fagioli essenzialmente privi di fitoemoagglutinina procedimento di estrazione e composizioni che lo contengono
ITMI20052450A1 (it) 2005-12-22 2007-06-23 Indena Spa Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono

Also Published As

Publication number Publication date
RU2015143561A (ru) 2017-04-19
JP2016517413A (ja) 2016-06-16
CA2900472A1 (en) 2014-10-09
WO2014165030A3 (en) 2014-12-04
US9290752B2 (en) 2016-03-22
EP2970404A2 (en) 2016-01-20
CN105008392A (zh) 2015-10-28
BR112015021588A2 (pt) 2017-07-18
HK1216539A1 (zh) 2016-11-18
US20140273157A1 (en) 2014-09-18
WO2014165030A2 (en) 2014-10-09

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