MX2015008757A - Controlled release formulations of lorazepam. - Google Patents
Controlled release formulations of lorazepam.Info
- Publication number
- MX2015008757A MX2015008757A MX2015008757A MX2015008757A MX2015008757A MX 2015008757 A MX2015008757 A MX 2015008757A MX 2015008757 A MX2015008757 A MX 2015008757A MX 2015008757 A MX2015008757 A MX 2015008757A MX 2015008757 A MX2015008757 A MX 2015008757A
- Authority
- MX
- Mexico
- Prior art keywords
- release
- lorazepam
- controlled release
- release formulations
- dosing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Abstract
Controlled release of lorazepam can provide enhanced dosing options including once daily dosing that provides 24 hour therapeutic effect under steady state conditions. The pharmaceutical composition can provide substantially zero order release and 90% release within 7 to 12 hours in a pharmaceutical dissolution test. The release can be achieved using polyethylene oxide as a matrix polymer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361750792P | 2013-01-09 | 2013-01-09 | |
US201361762836P | 2013-02-08 | 2013-02-08 | |
PCT/US2014/010863 WO2014110248A1 (en) | 2013-01-09 | 2014-01-09 | Controlled release formulations of lorazepam |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015008757A true MX2015008757A (en) | 2016-02-05 |
Family
ID=50030512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015008757A MX2015008757A (en) | 2013-01-09 | 2014-01-09 | Controlled release formulations of lorazepam. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2943186A1 (en) |
JP (1) | JP2016504391A (en) |
KR (1) | KR20150127037A (en) |
CN (1) | CN105188682A (en) |
AU (1) | AU2014205356A1 (en) |
BR (1) | BR112015016322A8 (en) |
CA (1) | CA2897313A1 (en) |
CL (1) | CL2015001921A1 (en) |
HK (1) | HK1213803A1 (en) |
IL (1) | IL239778A0 (en) |
MX (1) | MX2015008757A (en) |
PE (1) | PE20151431A1 (en) |
PH (1) | PH12015501533A1 (en) |
RU (1) | RU2015128914A (en) |
SG (1) | SG11201505352RA (en) |
WO (1) | WO2014110248A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019089330A1 (en) | 2017-11-01 | 2019-05-09 | Edgemont Pharmceuticals, Llc Trust | Alcohol-resistant oral pharmaceutical compositions of lorazepam |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL298071A (en) | 1963-06-04 | |||
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3786813A (en) | 1972-12-27 | 1974-01-22 | Alza Corp | Drug delivery device with self actuated mechanism for retaining device in selected area |
US4361545A (en) | 1979-05-21 | 1982-11-30 | Rowell Laboratories, Inc. | Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion |
KR850700212A (en) * | 1984-03-21 | 1985-12-26 | 죠지 드모트 | Sustained Release Pharmaceutical Wexel |
US4624847A (en) | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
US5009895A (en) | 1990-02-02 | 1991-04-23 | Merck & Co., Inc. | Sustained release with high and low viscosity HPMC |
US5945125A (en) | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
CO5140079A1 (en) * | 1998-10-14 | 2002-03-22 | Novartis Ag | PHARMACEUTICAL COMPOSITION OF SUSTAINED LIBERATION AND METHOD TO RELEASE A PHARMACEUTICALLY ACTIVE AGENT FROM SUSTAINED LIBERATION AND METHOD TO RELEASE A PHARMACEUTICALLY ACTIVE AGENT |
JP2004513975A (en) | 2000-12-05 | 2004-05-13 | マクグレゴール アレキサンダー | Hydrostatic delivery system for controlled release of active substance |
MXPA04000209A (en) | 2001-07-10 | 2005-03-07 | Teva Pharma | Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery. |
US6703045B2 (en) | 2001-08-21 | 2004-03-09 | Council Of Scientific & Industrial Research | Composition and method for maintaining blood glucose level |
BR0302017B1 (en) * | 2003-06-02 | 2014-10-29 | Ems Sigma Pharma Ltda | Sublingual pharmaceutical composition based on a benzodiazepine central receptor agonist |
KR100822519B1 (en) * | 2005-02-15 | 2008-04-16 | 주식회사종근당 | Gastric-retentive controlled release mono-matrix tablet |
-
2014
- 2014-01-09 PE PE2015001249A patent/PE20151431A1/en not_active Application Discontinuation
- 2014-01-09 JP JP2015551871A patent/JP2016504391A/en active Pending
- 2014-01-09 KR KR1020157020972A patent/KR20150127037A/en not_active Application Discontinuation
- 2014-01-09 CN CN201480012337.2A patent/CN105188682A/en active Pending
- 2014-01-09 RU RU2015128914A patent/RU2015128914A/en unknown
- 2014-01-09 WO PCT/US2014/010863 patent/WO2014110248A1/en active Application Filing
- 2014-01-09 AU AU2014205356A patent/AU2014205356A1/en not_active Abandoned
- 2014-01-09 CA CA2897313A patent/CA2897313A1/en not_active Abandoned
- 2014-01-09 BR BR112015016322A patent/BR112015016322A8/en active Search and Examination
- 2014-01-09 MX MX2015008757A patent/MX2015008757A/en unknown
- 2014-01-09 EP EP14702134.9A patent/EP2943186A1/en not_active Withdrawn
- 2014-01-09 SG SG11201505352RA patent/SG11201505352RA/en unknown
-
2015
- 2015-07-05 IL IL239778A patent/IL239778A0/en unknown
- 2015-07-06 CL CL2015001921A patent/CL2015001921A1/en unknown
- 2015-07-07 PH PH12015501533A patent/PH12015501533A1/en unknown
-
2016
- 2016-02-19 HK HK16101886.7A patent/HK1213803A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2014205356A1 (en) | 2015-07-30 |
BR112015016322A2 (en) | 2017-07-11 |
KR20150127037A (en) | 2015-11-16 |
CL2015001921A1 (en) | 2015-12-18 |
IL239778A0 (en) | 2015-08-31 |
HK1213803A1 (en) | 2016-07-15 |
EP2943186A1 (en) | 2015-11-18 |
RU2015128914A (en) | 2017-02-14 |
JP2016504391A (en) | 2016-02-12 |
CA2897313A1 (en) | 2014-07-17 |
SG11201505352RA (en) | 2015-08-28 |
CN105188682A (en) | 2015-12-23 |
BR112015016322A8 (en) | 2018-01-23 |
WO2014110248A1 (en) | 2014-07-17 |
PE20151431A1 (en) | 2015-09-23 |
PH12015501533A1 (en) | 2015-10-05 |
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