MX2015000473A - Combinacion de acido docosahexaenoico e indometacina para su uso como analgesico. - Google Patents
Combinacion de acido docosahexaenoico e indometacina para su uso como analgesico.Info
- Publication number
- MX2015000473A MX2015000473A MX2015000473A MX2015000473A MX2015000473A MX 2015000473 A MX2015000473 A MX 2015000473A MX 2015000473 A MX2015000473 A MX 2015000473A MX 2015000473 A MX2015000473 A MX 2015000473A MX 2015000473 A MX2015000473 A MX 2015000473A
- Authority
- MX
- Mexico
- Prior art keywords
- indomethacin
- docosahexaenoic acid
- analgesic
- combination
- agent
- Prior art date
Links
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 title abstract 6
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 title abstract 5
- 235000020669 docosahexaenoic acid Nutrition 0.000 title abstract 3
- 229960000905 indomethacin Drugs 0.000 title abstract 3
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 229940090949 docosahexaenoic acid Drugs 0.000 title abstract 2
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000001156 gastric mucosa Anatomy 0.000 abstract 1
- 230000002178 gastroprotective effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000003223 protective agent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición farmacéutica que comprende, como primer agente activo a la indometacina en combinación con el Ácido docosahexaenoico o DHA para crear un efecto superaditivo que potencializa el efecto analgésico, además de contribuir como agente gastroprotector disminuyendo las lesiones que comúnmente se presenta a través de daño en mucosa gástrica, perdidas de sangre o ulceraciones las cuales son producidas al administrar la indometacina como un medicamento común para el tratamiento terapéutico del dolor, el cual es generado por algún agente nocivo.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2015000473A MX2015000473A (es) | 2015-01-12 | 2015-01-12 | Combinacion de acido docosahexaenoico e indometacina para su uso como analgesico. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2015000473A MX2015000473A (es) | 2015-01-12 | 2015-01-12 | Combinacion de acido docosahexaenoico e indometacina para su uso como analgesico. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015000473A true MX2015000473A (es) | 2016-07-11 |
Family
ID=57219088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015000473A MX2015000473A (es) | 2015-01-12 | 2015-01-12 | Combinacion de acido docosahexaenoico e indometacina para su uso como analgesico. |
Country Status (1)
| Country | Link |
|---|---|
| MX (1) | MX2015000473A (es) |
-
2015
- 2015-01-12 MX MX2015000473A patent/MX2015000473A/es active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |