MX2012013966A - Hypochlorite denture compositions and methods of use. - Google Patents

Abstract

A solid composition including calcium and/or magnesium hypochlorite, a builder (e.g., one or more of carbonate, bicarbonate, sesquicarbonate), an acid, a water- soluble polymer, at least one anionic surfactant, and optionally, a hydrotrope. The composition does not include any potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, or carboxylic acids that also have hydroxyl, amino, amido, imino, or imido groups. Upon dissolution of the composition in water, the calcium and/or magnesium hypochlorite and acid react to form hypochlorous acid. The use of hypochlorous acid, rather than direct use of an alkaline or alkaline earth hypochlorite results in a composition that is typically acidic rather than basic, and that results in improved cleaning. The composition is particularly suited for cleaning and disinfecting dentures.

Description

HYPOCHLORITE COMPOSITIONS FOR POSTCIDAL DENTURES AND METHODS FOR YOUR USE CROSS REFERENCE TO RELATED REQUESTS The present application is a continuation of U.S. patent application serial number 12 / 620,932 filed on November 18, 2009 and entitled SOLID STRATIFIED WHITENING COMPOSITIONS. The present application also claims the benefit of U.S. patent application serial number 61 / 351,433, filed on June 4, 2010, entitled METHODS OF USE OF HYPOCHLOROUS ACID IN POST-DENTURE CLEANERS. Each of the above patent applications is hereby incorporated by reference in its entirety.

BACKGROUND OF THE INVENTION 1. Field of the invention The present invention relates generally to solid, single-layer cleaning compositions. These compositions can be used to clean and disinfect dentures, other dental instruments or to clean other oral surfaces (for example, a buccal elixir, endodontic disinfection). 2. Background and relevant technique Solid whitening compositions have progressed for decades and have created a large chemical industry dedicated to cleaning and disinfecting hard and soft surfaces. Very often N-chloro hydantoins, N-chloro isocyanurates, sodium hypochlorite and calcium hypochlorite are used in bleaching compositions for many companies because they are economical to produce and highly effective. However, these bleaching compositions have several disadvantages that limit their utility. Sodium hypochlorite is only available at room temperature. Calcium hypochlorite leaves residues. Hydantoins and chlorinated isocyanurates lack long-term solution stability and general malodour. All of these disadvantages present compositions that may not be preferred by consumers.

BRIEF SUMMARY OF THE INVENTION The invention claimed herein solves some of these problems in the art with compositions and methods related to denture cleaning compounds comprising hypochlorite in a single layer composition. It is anticipated that the composition may also be useful in other oral care settings, such as oral elixir and endodontic disinfectant. The use of calcium and / or magnesium hypochlorite in a single-layer composition (e.g., in the form of a tablet) as demonstrated herein minimizes and / or eliminates the formation of residues that are associated with other hypochlorite compositions. calcium. In addition, the compositions do not generate malodors typically associated with the use of chlorinated isocyanurates. The present invention also relates to a whitening faster than the typical use of halogenated hydantoins. The present invention also dissolves more rapidly than typical commercial products based on calcium hypochlorite or halogenated hydantoins.

An embodiment of the present invention comprises a single layer solid composition which includes: a) a hypochlorite which is selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) an enhancer that is selected from the group 'consisting of carbonate, bicarbonate, sesquicarbonate and. its mixtures; c) an acid selected from the group consisting of carboxylic acid, dicarboxylic acid, sulfonic acid, sulfate acid, phosphate acid and mixtures thereof; d) a water-soluble polymer selected from the group consisting of a polycarboxylate, sulfonated carboxylate, polysulfonate, polyvinylpyrrolidone, polypyridinium salt, polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; f) at least one hydrotrope; g) wherein the composition does not contain potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, carboxylic acids which also have one or more portions of hydroxyl, amino, amido, imino group , or imido; h) and where the composition contains only one layer.

Another embodiment of the present invention comprises a solid composition of a single layer consisting basically of a) a hypochlorite selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) an improver that is selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof; c) an acid selected from the group consisting of carboxylic acid, dicarboxylic acid, sulphonic acid, sulfate acid, phosphate acid and their mixtures; d) - a water-soluble polymer selected from the group consisting of a polycarboxylate, a sulfonated carboxylate, a polysulfonate, a polyvinylpyrrolidone,. a polypyridinium salt, a polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; "f) at least one hydrotrope; g) optionally, a harvester selected from the group consisting of a hydroxide, an oxide, a silicate, a phosphate, a borate and their mixtures; h) optionally, colorants, perfumes, sequestrants, anticorrosive agents, lubricants, binders, fillers, disintegration aids, preservatives, desiccants and their mixtures.

Another embodiment of the present invention relates to a solid single-layer composition consisting of: a) a hypochlorite which is selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) an improver selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof; c) an acid selected from the group consisting of carboxylic acid, dicarboxylic acid, sulphonic acid, sulfate acid, phosphate acid and mixtures thereof; d) a water-soluble polymer selected from the group consisting of a polycarboxylate, a sulfonated carboxylate, a polysulfonate, a polyvinylpyrrolidone, a polypyridinium salt, a polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; f) optionally, at least one hydrotrope; g) optionally, a com pound selected from the group consisting of a hydroxide, an oxide, a silicate, a phosphate, a borate and their mixtures; h) optionally, colorants, perfumes, sequestrants, anticorrosive agents, lubricants, binders, fillers, disintegration aids, preservatives, desiccants and their mixtures.

Because the composition includes calcium and / or magnesium hypochlorite and an acid, hypochlorous acid is formed upon dissolution of the composition in water. As such, the disinfecting and cleansing properties of the composition derive from the hypochlorous acid formed in situ, instead of the hypochlorite alone. The use of hypochlorous acid, instead of the direct use of an alkaline or alkaline earth hypochlorite (eg, calcium hypochlorite) results in a composition that is acidic rather than basic and that provides superior efficacy.

Other features and advantages of the present invention will become apparent to those skilled in the art from the detailed description of the preferred embodiments below, when considered in conjunction with the appended claims.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS I. Definitions Before describing the present invention in detail, it should be understood that the present invention is not limited to the particular process systems or parameters exemplified, which, of course, may vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any way.

All publications, patents and patent applications cited herein, before or below, are hereby incorporated by reference in their entirety, to the same extent as if it were specifically and individually indicated that each publication, patent or application for individual patent is incorporated by reference.

It is noted that as used herein and in the appended claims, the singular forms "a", "an" and "the" include plural referents unless clearly expressed otherwise in the context .

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by the person skilled in the art to which the present invention pertains. Although various methods and materials similar or equivalent to those described herein may be used in the practice of the present invention, preferred methods and materials are described herein.

In the application, the effective amounts are generally those amounts expressed as the ranges or levels of ingredients in the descriptions below. Unless indicated otherwise, the amounts expressed in percent (%) are in percent by weight (based on 100% active) of the composition alone, without representing any substrate weight. Each of the aforementioned components and substrates of the composition are discussed in detail below. In addition, the invention also encompasses the steps of the method for the use of the compositions described in the present application.

The term "comprising", which is a synonym of "including", "containing" or "characterized by" includes or encompasses and does not exclude additional elements or steps of the method not mentioned. See MPEP 2111.03. See, for example, Mars Inc. v. H.J. Heinz Co., 377 F.3d 1369, 1376, 71 USPQ2d 1837, 1843 (Fed. Cir. 2004) ("as the term 'comprising', the terms 'containing' and 'mixing' are undefined"). Invitrogen Corp. v. Biocrest Mfg., LP, 327 F.3d 1364, 1368, 66 USPQ2d 1631, 1634 (Fed. Cir. 2003) ("The transition 'comprising' in a claim to the method indicates that the claim is indefinite and allows additional steps" .); Genentech, Inc. v. Chiron Corp., 112 F.3d 495, 501, 42 USPQ2d 1608, 1613 (Fed. Cir. '19'97) See MPEP 2111.03. ("Understanding" is a term of the technique used in the language of the claims which means that the elements named t are essential, but other elements may be added and still form a construction within the scope of the claim.); Moleculon Research Corp. v. CBS, Inc., 793 F.2d 1261, 229 USPQ 805 (Fed. Cir. 1986); In re Baxter, 656 F.2d 679, 686, 210 USPQ 795, 803 (CCPA 1981); Ex parte Davis, 80 USPQ 448, 450 (Bd. App. 1948). See MPEP 2111.03.

The term "basically consisting of, as used herein, limits the scope of a claim to specified materials or steps" and those that do not materially affect the basic (s) and new characteristic (s). ) of the claimed invention. In re Herz, 537 F.2d 549, 551-52, 190 USPQ 461, 463 (CCPA 1976). See MPEP 2111.03.

The term "consisting of", as used herein, excludes any element, step or ingredient not specified in the claim. In re Gray 53 F.2d 520, 11 USPQ 255 (CCPA 1931); Former Part Davis, 80 USPQ 448, 450 (Bd. App. 1948). See MPEP 2111.03.

The term "surfactant", as used herein, is intended to mean and include a substance or compound that reduces the surface tension when dissolved in water or aqueous solutions, or that reduces the interfacial tension between two liquids, or between a liquid and a solid. Thus, the term "surfactant" includes anionic, nonionic, cationic, zwitterionic and / or amphoteric agents.

II. Introduction The present . invention relates to a single layer solid composition. The solid composition of. a single layer comprises calcium hypochlorite, magnesium hypochlorite or mixtures thereof, an acid, a water-soluble polymer and an anionic surfactant. Optional ingredients may be added to the composition to improve the effectiveness of the solid composition of a single layer. After the dissolution of the composition in water, the calcium and / or magnesium hypochlorite and the acid react to form hypochlorous acid. The composition may be particularly suitable for use in the disinfection of dentures or other dental instruments, although it is contemplated that the composition may also be useful in other oral care environments such as a buccal elixir and as a root canal disinfectant.

The use . of hypochlorous acid, instead of the direct use of an alkaline or alkaline earth hypochlorite (eg, calcium hypochlorite) results in a composition that is typically acidic rather than basic. This lower pH accelerates the speed of antimicrobial activity, improves the extraction of the plate and biofilms that include its conditioning layer and increases the extraction of stains from food, beverages and tobacco. The complete extraction of the biofilms including their conditioning layer increases the incubation time required for the bacteria to stick back to the denture to reform a biofilm when it is subsequently exposed to bacteria again. In addition, the lower pH also increases the extraction of dental calculus and other calcium deposits difficult to remove. This is because the solubility of calcium is significantly greater within the acidic environment.

Because hypochlorous acid is more effective than hypochlorite ion, a lower concentration of hypochlorous acid can be used. This largely eliminates the formation of unpleasant odors from the reaction of the hypochlorite ion and the proteins. In addition, the hypochlorous acid works more quickly so that shorter contact times with the cleaning solution produce the desired results. The hypochlorous acid solutions by virtue of their lower effective concentration and lower pH are also less corrosive to some materials used to build dentures and dental instruments.

Although the pH of the mixed and prepared composition can be as high as about 9, preferably, the pH of the hypochlorous acid disinfecting composition is between about 5 and about 8. In another embodiment, the pH of the hypochlorous acid disinfecting composition is In about one embodiment, the pH is preferably acidic (ie, less than about 7), more preferably between about 5.5 and about 6.5.

Generally, the concentration of hypochlorous acid will be selected to remove stains, biofilms and kill or extract at least 99.9% of bacteria, viruses and fungi. The concentration will depend on the use of the instructions for the product. For example, a product designed to soak dentures overnight would contain at least 10 ppm, preferably more than about 20 ppm, more preferably more than about 30 ppm, and more preferably more than about 50 ppm of hypochlorous acid. A product designed to work in 3 to 5 minutes would contain at least 50 ppm, preferably more than about 100 ppm, more preferably more than about 150 ppm, and more preferably more than about 300 ppm of hypochlorous acid. To minimize the ability to form unpleasant odors or to damage the surfaces in case of spillage, the maximum concentration is about 1500 ppm, preferably less than about 1000 ppm, more preferably less than about 600 ppm, and preferably less than about 400 ppm. of hypochlorous acid.

III. Oxidizers The solid composition of a single layer contains calcium hypochlorite, magnesium hypochlorite or mixtures thereof.

These hypochlorite salts include anhydrous varieties as well as various hydrates, double salts such as monobasic and dibasic forms and triple salts. The hypochlorite salts can be crystalline or amorphous. The solid composition of a single layer does not contain any other type of hypochlorite such as sodium hypochlorite, lithium hypochlorite or potassium hypochlorite. Accordingly, the composition does not contain any N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates or carboxylic acids also having hydroxyl, amino, amido, imino or imido groups. More specific examples of such excluded components include hypobromites, hypohydeites, chlorinated trisodium phosphate dodecahydrates, potassium and sodium dichloroisocyanurates, trichlorocyanuric acid, N-chloroimides, N-chloroamides, N-chlorosulfamide, N-chloroamines, chlorohydantoins as dichlorodimethyl hydantoin , chlorobromo dimethylhydantoin, and bromine compounds corresponding to the above chloro compounds.

The compositions of the present invention do not require a whitening activator. The term "whitening activator", herein means a compound that reacts with peroxygen bleaching as hydrogen peroxide to form a peracid. The peracid then formed constitutes activated whitening. Whitening activators which should not be used in the composition include, but are not limited to, those belonging to the class of esters, amides, imides or anhydrides. Examples of whitening activators that should not be used in the composition include, but are not limited to, TAED activators, sodium 3,5,5-trimethylhexanoyloxybenzene sulfonate, diperoxydodecanoic acid, peroxyadipic acid nonyl- amide, peroxyadipic acid nonyl- amide. , n-nonanoyloxybenzenesulfonate (NOBS), acetyl triethyl citrate (ATC), n-alkyl alkyl ammonium acetonitrile. Additional examples of whitening activators that should not be used in the composition include, but are not limited to, N-acyl caprolactams which are selected from the group consisting of a substituted or unsubstituted benzoyl caprolactam, octanoyl caprolactam, nonanoyl caprolactam, hexanoyl caprolactam, decanoyl caprolactam, undecenoyl caprolactam, formyl caprolactam, acetyl caprolactam, propanoyl caprolactam, butanoyl caprolactam, pentanoyl caprolactam or mixtures thereof.

In one embodiment, calcium hypochlorite, magnesium hypochlorite or mixtures thereof are present in the composition in an amount of less than about 50%. For example, calcium and / or magnesium hypochlorite can be present in the composition in an amount ranging from about 0.1% to about 50%, about 0.1% and about 45%, about 0%. , 1% and about 40%, about 0.1% and about 30%, about 0.1% and about 25%, about 0.1% and about 20%, about 0.1 % and about 15%, about 0.1% and about 10%, about 0.1% and about 5%, about 5% and about 20%, about 5% and about 15% , about 10% and about 20%, about 10% and about 15¾ > or approximately 15% and approximately 20%.

IV. Improvers The composition may contain an improver. The improver may be present in the cleaning composition in an amount ranging from about 10% and approximately one! 30%, approximately 20% and approximately 90%, approximately 20% and approximately 80%, approximately 20% and approximately 60%, approximately 20% and approximately 50%, approximately 30% and approximately 60%, about 35% and about 55%, about 40% and about 50%, about 20% and about 30%, about 30% and about 50%, about 30% and about a 45%, approximately 30% and approximately 40%, approximately 20% and approximately 60%, approximately 25% and approximately 60%, approximately 20% and approximately 40%, or approximately 20% and approximately .30%. The improver can be selected from inorganic builders such as carbonate, bicarbonate, sesquicarbonate and mixtures thereof. More specifically, the improver may comprise a carbonate, bicarbonate, sesquicarbonate of one or more alkali metals. The improver can be found in its anhydrous form or in any of its stable hydrates and can be crystalline or amorphous.

The inclusion of an improver is advantageous, since it can increase the effectiveness of the surfactant. The improver may also function as a softener, a sequestering agent, a buffering agent or a pH adjusting agent in the cleaning composition. A variety of buffers or buffers can be used and these include, but not limited to, phosphate-silicate compounds, zeolites, alkali metals, ammonium and substituted ammonium polyacetates, trialkaline salts of nitrilotriacetic acid, carboxylates, polycarboxylates, carbonates, bicarbonates, polyphosphates, aminopolycarboxylates, polyhydroxy sulfonates, and starch derivatives . When using mej orators,. These include, but are not limited to, organic acids, mineral acids, alkaline or alkaline earth metal salts, silicate, metasilicate, polysilicate, borate, sulfate, hydroxide, carbonate, carbamate, phosphate, polyphosphate, pyrophosphate, triphosphate, tetraphosphate, ammonium, hydroxide, monoethanolamine, monopropanolamine, diethanolamine, dipropanolamine, triethanolamine and 2-amino-2-methylpropanol. Other suitable buffers include ammonium carbamate and acetic acid. Mixtures of any of the above may also be acceptable. Suitable sources of inorganic buffers / alkalinity include ammonium, alkali metal carbonates and alkali metal phosphates, for example, sodium carbonate, sodium polyphosphate. For additional buffers see O 95/07971, which is incorporated herein by reference. Other adjustment agents of preferred pH include sodium or potassium hydroxide. The term "silicate" is intended to encompass silicate, metasilicate, polysilicate, aluminosilicate, and the like. Preferred buffers / buffers of the single layer solid composition include carbonate, bicarbonate, sesquicarbonate and mixtures thereof.

V. Water soluble polymers The composition may contain a water soluble polymer. Examples of water-soluble polymers include, but are not limited to, polycarboxylate, sulfonated carboxylate, polysulfonate, polyvinylpyrrolidone ("PVP"), a polypyridinium salt, a polyquaternary ammonium salt, and mixtures thereof.

Examples of polycarboxylates include, but are not limited to, polymers with sufficient carboxylate ions to achieve solubility in water. The carboxylate ions can be derived from various monomers including acrylic acid, methacrylic acid, maleic acid and maleic anhydride. Copolymers of different carboxylate-containing monomers are also suitable as copolymers with non-carboxylate-containing monomers such as methacrylate, acrylonitrile, styrene, ethylene; propylene and many others. Mixtures of polymers containing carboxylate can also be used.

In one embodiment, the molecular weight of the water soluble polymer can be between about 1,000 and about 10,000 daltons, about 1,000 and about 8,000 daltons, about 1,000 and about 6,000 daltons, about 1. 000 'and approximately 5,000 daltons, approximately 1,000 and approximately 4,000 daltons, approximately 1,000 and approximately 2,000 daltons, approximately 2,000 and approximately 10,000 daltons, approximately 2,000 and approximately 8. 000 daltons, approximately 2,000 and approximately 6,000 daltons, approximately 2,000 and approximately 5,000 daltons, approximately 2,000 and approximately 4,000 daltons, approximately 3,000 and approximately 10,000 daltons, approximately 3,000 and approximately 8,000 daltons, approximately 3,000 and approximately 6,000 daltons, approximately 3,000 and approximately 5,000 daltons, approximately 3,000 and approximately 4,000 daltons tons, approximately 4,000 and approximately 10,000 daltons, approximately 4,000 and approximately 8,000 daltons, approximately 4,000 and approximately 6,000 daltons, approximately 5,000 and approximately 10,000 daltons, approximately 5,000 and approximately 7.! 500 daltons, or approximately .7 .500 and approximately 10,000 daltons.

The water-soluble polymer can be present in an amount ranging from about 0.1% to about 50%, about 0.1% and about 40%, about 0.1% and about 30%, about 0.1% and about 20%, about 0.1% and about 15%, about 0.1% and about 10%, about 1% and about 10%, about 1%. % and about R2o-, about 1% and about 3%, about 5% and about 60%, about 5% and about 50%, about 5% and about 40%, about 5%. % and about 30%, about 5% and about 20%, about 5% and about 10%, about 10% and about 60%, about 10% and about 50%, about 10%. % and approximately 40%, approximately 10% and about 30%, about 10% and about 20%, about 20% and about 60%, about 20% and about 50%, about 20% and about 40%, about 20% and about 30%, about 30% and about 60%, about 30% and about 50%, about 30% and about 40%, or about 40% and about 60%.

SAW. Acids The composition may contain an acid. Examples of acids that can be used with the present invention include, but are not limited to, carboxylic acid, dicarboxylic acid, sulfonic acid, acid sulfate, acid phosphate and mixtures thereof. Specific examples of acids include, but are not limited to, succinic acid, glutaric acid, 3-pyridine sulfonic acid, dodecyl benzene sulfonic acid and mixtures thereof.

Notably, the composition does not contain carboxylic acids having one or more portions of hydroxyl, amino, amido, imino or imido groups. Examples of acids that should not be used in the composition include, but are not limited to, citric acid, tartaric acid and alanine.

The acid can be present in an amount of at least 30% and in one embodiment at least 50% of the composition. For example, the acid may be present in an amount ranging from about 30% to about 80%, about 30% and about 70%, about 30% and about 60%, about 30% and about 50%, or about 40% and about 80%, about 40% and about 70%, about 40% and about 60%, about 40% and about 50%, about 50% and about 80%, about 50% and about 70%, or about 50% and about 60%.

In one embodiment, the acid is present in an amount of at least about 50% (for example, from about 50% to about 60%) and the calcium and / or magnesium hypochlorite is present "in an amount about 0.1% and about 5% This results in the relatively low but effective concentration desired of hypochlorous acid after dissolution of the composition in water.

VII. Crosslinked polymers expandable in water The composition may optionally contain a crosslinked polymer expandable in water. Examples of water-expandable polymers include, but are not limited to, cross-linked polycarboxylate, sulfonated cross-linked carboxylate, cross-linked polysulfonate, cross-linked PVP, cross-linked polypyridinium salt, cross-linked polyquaternary ammonium salt, cellulose, cross-linked carboxymethylcellulose, sodium carboxymethylcellulose, and mixtures thereof.

The molecular weight of the water expandable polymer can be between about 1,000 and about 10,000 daltons, about 1,000 and about 8,000 daltons, about 1,000,000 and about 6,000 daltons, about 1,000 and approximately 5,000 daltons, approximately 1,000 and approximately 4,000 daltons, approximately 1,000 and approximately 2,000 daltons, approximately 2,000 and approximately 10,000 daltons, approximately 2,000 and approximately 8,000 daltons, about 2,000 and about 6,000 daltons, about 2,000 and about 5,000 daltons, about 2,000 and about 4,000 daltons, about 3,000 and about 10,000 daltons, about 3,000 and about 8,000 daltons , approximately 3,000 and approximately 6,000 daltons, approximately 3,000 and approximately 5,000 daltons, approximately 3,000 and approximately 4,000 daltons, approximately 4,000 and approximately 10,000 daltons, approximately 4,000 and approximately 8,000 daltons, approximately 4,000 and approximately 6,000 daltons, approximately 5,000 and approximately 10,000 daltons, approximately 5,000 and approximately 7. 500 daltons, or approximately 7,500 and approximately 10,000 daltons.

The water expandable polymer can optionally be present in an amount ranging from about 0.1% to about 60%, about 0.1% and about 50%, about 0.1% and. about 40%, about 0.1% and about 30%, about 0.1% and about 20%, about 0.1% and about 15%, about 0.1% and about 10%, approximately 0.5% and approximately 10%, approximately 0.5% and approximately 5%, approximately 0.5% and approximately 3%, approximately 5% and approximately 60% approximately a 5% and approximately about 50% about 5% and about 40% about 5% and about 30% about 5% and about 20% about 5% and about 10% about 10% and about about 60% about 10% and about 50% about 10% and about 40% about 10% and about 30% about 10% and about 20% about 20% and about 60% about 20% and about about 50% about 20% and about 40% about 20% and about 30% about 30% and about 60% about 30% and about 50% about 30% and about 40% about 40% and approximately 60%.

VIII. Surfactants The composition may contain one or more anionic surfactants. In some embodiments, one or more additional surfactants may be included which are selected from nonionic, cationic, ampholytic, amphoteric and zwitterionic surfactants and mixtures thereof, although in one embodiment no nonionic surfactant is included. A typical list of the anionic, ampholytic and zwitterionic classes and species of these surfactants is provided in U.S. Patent No. 3,929,678 to Laughlin and Heuring. A list of suitable cationic surfactants is provided in U.S. Patent No. 4,259,217 to Murphy. Each of the above patents is incorporated herein by reference. The surfactants may be present at a level of from about 0.1% to about 25%, from about 0.1% to about 20%, from about 0.1% to about 15%, of about 0.1% to about 10%, from about 0.1% to about 5%, from about 5% to about 20%, from about 5% to about 15%, of about 5% to about 10%, from about 10% to about 20%, from about 10% to about 15%, or about 15%. to approximately 20%.

The composition comprises an anionic surfactant. Basically, any anionic surfactant useful for detergent effects in the cleaning composition can be used. These may include salts (including, for example, sodium, potassium, ammonium and substituted ammonium salts such as mono-, di- and triethanolamine salts) of the anionic sulfate, sulfonate, carboxylate and sarcosinate surfactants. The anionic surfactants may comprise a sulfonate or sulfate surfactant. The anionic surfactants may comprise an alkyl sulfate, a linear or branched alkyl benzene sulphonate or an alkyldiphenyloxide disulfonate, as described herein.

Other anionic surfactants include the isethionates such as acyl isethionates, N-acyl taurates, tauride metal fatty acid amides, alkyl succinates and sulfosuccinates, sulfosuccinate monoesters (for example, saturated or unsaturated C12-Ci8 monoesters), sulfosuccinate diesters (e.g. , saturated or unsaturated C6-C14 diesters) and N-acyl sarcosinates. Resin acids and hydrogenated resin acids may also be suitable, such as rosin, hydrogenated rosin and hydrogenated resin acids and resin acids present in or derived from tallow oil, although in one embodiment no resin is included. Suitable anionic sulfate surfactants for use herein include the linear and branched primary and secondary alkyl sulfates, alkyl ethoxy sulfates, fatty oleoyl glycerol sulphates, alkyl phenol ethylene oxide ether sulphates, acyl C5-Ci7-N-- ( Ci-Ci alkyl) and -N-- (hydroxyCi-C2) glucamine sulfates and sulfates of alkyl polysaccharides such as the alkyl polyglucoside sulfates (the non-sulphonated nonionic compounds described herein). The alkyl sulfate surfactants may be selected from the linear and branched C 1 -C 8 alkyl sulfates, the branched chain C 1 -C 5 alkyl sulfates, or the straight chain C 2 -C 4 alkyl sulfates.

The alkyl toxyl sulfate surfactants can be selected from the group consisting of cyclo-Ci8 alkyl sulfates which were ethoxylated with 0.5 to 20 moles of ethylene oxide per molecule. The alkyl ethoxysulfate surfactant may be a Cn-Ci8 or C11-C15 alkyl sulfate which was ethoxylated with 0.5 to 7 or 1 to 5 moles of ethylene oxide per molecule. One aspect of the invention employs mixtures of alkyl sulfate and / or sulfonate and alkyl ethoxysulfate surfactants. Such mixtures were disclosed in PCT International Patent Application No. WO 93/18124, incorporated herein by reference.

Suitable anionic sulphonate surfactants for use herein include linear C5-C20 alkylbenzene sulfonate salts, alkyl ester sulfonates, primary or secondary C6-C22 alkane sulphonates, C6-C24 olefin sulphonates, sulfonated polycarboxylic acids, alkyl glycerol sulfonates, acyl glycerol acid sulfonates, oleyl glycerol fatty sulfonates and mixtures thereof. Suitable anionic carboxylate surfactants include the alkyl ethoxy carboxylates, the alkyl polyethoxy polycarboxylate surfactants and the soaps (alkyl carboxyls), especially certain secondary soaps as described herein. Alkyl ethoxy carboxylates include those with the formula: RO (CH2CH20) xCH2COO "M + where R is an alkyl group at Cie, x ranges from 0 to 10, and the late distribution of ethoxy is such that, on a basis by weight, the amount of material where x is 0 is less than 20% and M is a cation. Suitable alkyl polyethoxypolycarboxylate surfactants include those having the formula RO- (CHR1-CHR2--0) x -R3 wherein R is a C6 to Cis alkyl group, x is from 1 to 25, R1 and R2 are selected from the group it consists of hydrogen, methyl acid radical, succinic acid radical, hydroxysuccinic acid radical and mixtures thereof, and R3 is selected from the group consisting of hydrogen, substituted or unsubstituted hydrocarbon having between 1 and 8 carbon atoms and mixtures thereof .

Suitable soap surfactants include secondary soap surfactants containing a carboxyl unit connected to a secondary carbon. Secondary soap surfactants for use herein are water-soluble members selected from the group consisting of water-soluble salts of 2-methyl-1-undecanoic acid, 2-ethyl-1-decanoic acid, 2-methyl-1-undecanoic acid, propyl-l-nonanoic acid, 2-butyl-l-octanoic acid and 2-pentyl-1-heptanoic acid. Certain soaps may also be included as suds suppressors.

Other suitable anionic surfactants are the alkali metal sarcosinates of formula R-CO R1) CH-) COOM, where R is a straight or branched C5-C17 alkyl or alkenyl group, R1 is a C1-C4 alkyl group and M is an ion of alkali metal. Examples are the myristyl and oleoyl methyl sarcosinates in the form of their sodium salts.

Other suitable surfactants include fatty acid sarcosinates which are mild, biodegradable anionic surfactants derived from fatty acids and sarcosine (amino acid). Sarcosine is the N-methyl derivative of glycine. Sarcosine is a natural amino acid found in muscles and other tissues. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. In a preferred embodiment, the sarcosines are acyl sarcosines. Examples of acyl sarcosinate include, but are not limited to, cocoyl sarcosine, lauroyl sarcosine, myristoyl sarcosine, oleoyl sarcosine, stearoyl sarcosine which are modified fatty acids. Acyl sarcosine salts refer to acyl sarcosinates. The acyl sarcosinates useful in the. present include, for example, those that have the formula: RCON (CH3) CH2COOX where R is an alkyl or alkenyl having from 8 to 22 carbon atoms, preferably from 12 to 18 carbon atoms, more preferably from 12 to 14 carbon atoms; and X is sodium, potassium, ammonium or triethanolamine.

Examples of acyl sarcosinates which can be used with the present invention include, but are not limited to, sodium sarcosinate coccil, lauroyl sodium sarcosinate and sodium myristoyl sarcosinate, sodium oleoyl sarcosinate, sodium stearoyl sarcosinate, ammonium coccium sarcosinate, lauroyl · Ammonium sarcosinate and ammonium-ammonium sarcosinate, oleoyl sarcosinate and ammonium stearoyl sarcosinate. Preferred commercially available acyl sarcocinates include, but are not limited to, for example, sodium lauroyl sarcosinate having the trade name HAMPOSYL L30 available from Hampshire Chemicals, and sodium cocoyl sarcosinate having the trade name HAMPOSYL C30 found available at Hampshire Chemicals.

Other suitable surfactants include fatty alcohol sulfates having a higher alcohol or alkyl group usually in the range of 10 to 18 carbon atoms. The cation will almost invariably be sodium or will include sodium, although other cations such as triethanolamine, potassium, ammonium, magnesium or calcium can also be used. Preferred fatty alcohol sulfates are those where the fatty alcohol is basically saturated and has a carbon content in the range of 10 to 18 carbon atoms, preferably 10 or 12 to 14 or 16 carbon atoms, such as 12 to 16. or that is derived from coconut oil, palm oil or palm kernel oil. Lauryl sulfates and particularly sodium lauryl sulfate are preferred primary detergents but such designation can also be applied to detergents where the length of the carbon chain of the alcohol is not limited to 12 carbon atoms, but is mainly (more than 50). % and usually more than 70 or 75%) of 12 to 14 carbon atoms. These materials can be obtained from natural sources such as coconut oil and palm kernel oil. In one embodiment, the fatty alcohol sulfate is C 12 -C 18 fatty alcohol sulfate. In another embodiment, the fatty alcohol sulfate is a C12-Ci6 fatty alcohol sulfate. In another embodiment, the fatty alcohol sulfate is a C12-C1 fatty alcohol sulfate. In another embodiment, the fatty alcohol is a Ci2 fatty alcohol sulfate. In another embodiment, the fatty alcohol sulfate is sodium lauryl sulfate. In a specific embodiment, the fatty alcohol sulfate is a sodium coconut fatty alcohol sulfate.

Amphoteric surfactants suitable for use herein include amine oxide surfactants and alkyl amphocarboxylic acids. Suitable amine oxides include those compounds having the formula R3 (OR4) XN0 (R5) 2, wherein R3 is selected from an alkyl, hydroxyalkyl, acylamidopropyl and alkylphenyl group or mixtures thereof, containing from 8 to 26 carbon atoms; R 4 is an alkylene or hydroxyalkylene group containing 2 to 3 carbon atoms or mixtures thereof, x is from 0 to 5, preferably from 0 to 3; and each R 5 is an alkyl or hydroxyalkyl group containing 1 to 3, or a polyethylene oxide group containing 1 to 3 ethylene oxide groups. Suitable amine oxides are "alkylCiocydimethylamine oxide and acylCio-Cisamido alkyldimethylamine oxide." A suitable example of an alkylalanodicarboxylic acid is MIRANOL C2M Cone, manufactured by Miranol, Inc., Dayton, N.J.

Zwitterionic surfactants can also be incorporated into cleaning compositions. These surfactants can be broadly described as derivatives of secondary and tertiary amines, derivatives of heterocyclic secondary and tertiary amines, or derivatives of quaternary ammonium, quaternary phosphonium or tertiary sulfonium compounds. The betaine and sultaine surfactants are exemplary zwitterionic surfactants for use herein.

Suitable betaines are those compounds having the formula R (R1) 2N + R2COO ~ where R is a C6-Ci8 hydrocarbyl group, each R1 is typically Ci-C3 alkyl and R2 is a C1-C5 hydrocarbyl group. Suitable betaines are dimethylCi2-Ci8ammonium hexanoate and acylCio-Ci8amidopropane (or ethane) dimethyl (or diethyl) betaines. Complex betaine surfactants are also suitable for use herein.

Suitable cationic surfactants to be used herein include quaternary ammonium surfactants. The quaternary ammonium surfactant can be a C6-C16, or C6-C10 mono- or N-alkyl or alkenyl ammonium surfactant where the remaining N positions are substituted with methyl, hydroxyethyl or hydroxypropyl groups. Also suitable are monoalkoxylated and bisalkoxylated amine surfactants. Additional suitable cationic surfactants include coconut fatty acid diethanolamine, hydrogenated palm quaternary ester and cationic ethoxylated fatty acids.

Another suitable group of cationic surfactants that can be used in cleaning compositions are cationic ester surfactants. The cationic ester surfactant is a compound having surfactant properties comprising at least one ester linkage (i.e., --C00--) and at least one cationically charged group. Suitable cationic ester surfactants, including choline ester surfactants, were disclosed, for example, in U.S. Patent Nos. 4,228,042, 4,239,660 and 4,260,529, each of which is incorporated herein by reference. The ester bond and the cationically charged group can be separated from each other in the surfactant molecule by a spacer group consisting of a chain comprising at least three atoms (i.e., a chain length of three atoms) or three to eight atoms or three to five atoms or three atoms. The atoms forming the chain of the spacer group are selected from the group consisting of carbon, nitrogen and oxygen atoms and their mixtures, with the proviso that any nitrogen or oxygen atom in said chain is connected only with carbon atoms in the chain. chain. Accordingly, spacer groups having, for example, bonds -0--0-- (ie, peroxide), --N - N--, and - - O - are excluded, while the spacer groups having, for example, -CH2-O-, CH2- and -CH2-NH-CH2- bonds. The chain of the spacer group may comprise only carbon atoms, or the chain may be a hydrocarbyl chain.

The cleaning composition may comprise cationic monoalkoxylated amine surfactants, for example, of the general formula: wherein R 1 is an alkyl or alkenyl moiety that "contains from about 6 to about 18 carbon atoms, or from 6 to about 16 carbon atoms, or from about 6 to about 14 carbon atoms; R2 and R3 are each independently alkyl groups containing from one to about three carbon atoms, for example, methyl, for example, both R2 and R3 are methyl groups; R 4 is selected from hydrogen, methyl and ethyl; X "is an anion such as chloride, bromide, methylsulfate, sulfate, or the like, to provide electrical neutrality, A is an alkoxy group, especially an ethoxy, propoxy or butoxy group, and p is from 0 to about 30, or from 2 to about 15, or from 2 to about 8. The group APR4 in the formula can have p = l and is a hydroxyalkyl group, which has no more than 6 carbon atoms where the --OH group is separated from the quaternary ammonium nitrogen atom by no more than 3 carbon atoms Suitable APR4 groups are -CH2CH2-OH, -CH2CH2CH2-OH, -CH2CH (CH3) -OH and -CH (CH3) CH2-OH The suitable R1 groups are alkyl groups linear, for example, linear R1 groups having from 8 to 14 carbon atoms.

The cationic monoalkoxylated amine surfactants suitable for use herein are of the formula R1 (CH3) (CH3) N + (CH2CH20) 2_5HX ~ where R1 is hydrocarbylCi0-Ci8 and mixtures thereof, especially cyclo-Ci4 alkyl or C12 and C12 alkyl; X is any convenient anion to provide a charge balance, for example, chloride or bromide.

As mentioned above, compounds of the foregoing type include those where the units of ethoxy (CH2CH2O) (EO) are replaced with butoxy units, isopropoxy [CH (CH3) CH20] and [CH2CH (CH3) 0] (i- Pr) or n-propoxy units (Pr), or mixtures of EO and / or Pr units and / or i-Pr.

The cationic bisacloxylated amine surfactant may have the general formula: R1R2N + ApR3A + qRX "wherein R1 is an alkyl or alkenyl portion containing from about 8 to about 18 carbon atoms, or from 10 to about 16 · carbon atoms, or from about 10 to about 14 carbon atoms, R 2 is an alkyl group containing from one to three carbon atoms, for example, methyl, R 3 and R 4 can vary independently and are selected from hydrogen, me and e, X "is an anion such as chloride, bromide, mesulfate, sulfate, or the like, sufficient to provide electrical neutrality, A and A 'can vary independently and each is selected from C 1 -C 4 alkoxy, for example, ethoxy ( i.e., -CH2CH20--), propoxy, butoxy and mixtures thereof, p is from 1 to about 30 or from about 4 and q is from 1 to about 30 or from 1 to about 4 or both p and q are 1.

The cationic bisalkoxylated amine surfactants suitable for use herein are of formula R ^ HaN "(CH2CH2OH) (CH2CH2OH) X" 'where R1 is hydroxycarbylCi0-Ci3 and mixtures thereof, or alkylCio, C12, C1 and mixtures thereof X "is any convenient anion for providing charge equilibrium, eg, chloride With reference to the general cationic bisalkoxylated amine structure mentioned above, since in one example the compound R1 is derived from fatty acids of an alkylCi2- Ci4 (coco), R2 is methyl and APR3 and A'qR4 are each monoethoxy.

Other cationic bisalkoxylated amine surfactants useful herein include compounds of the formula: R1R2N + - (CH2CH20) pH - (CH2CH2O) qH X "wherein R1 is hydroxycarbylCi0-Ci8 or Cio-Cn alkyl, independently p is 1 to about 3 and q is 1 to about 3, R 2 is C 1 -C 3 alkyl, for example, metal, and X 1 is an anion, for example, chloride or bromide.

Other compounds of the foregoing type include those where the units of ethoxy (CH2CH20) (EO) are replaced with butoxy units (Bu), isopropoxy [CH (CH3) CH20] and [CH2CH (CH3) 0] (i-Pr) or n-propoxy units (Pr), or mixtures of units EO and / or Pr and / or i-Pr.

In one embodiment, the compositions of the invention may include at least one fluorosurfactant that is selected from nonionic fluorosurfactants, cationic fluorosurfactants, and mixtures thereof that are soluble or dispersible in the aqueous compositions shown herein, sometimes compositions that do not include detersive surfactants. additional or additional organic solvents or both. Suitable nonionic fluorosurfactants are among the materials currently marketed under the name FLUORAD (ex 3M Corp.) Exemplary fluorosurfactants include those sold as FLUORAD FC-740, generally described as fluorinated alkyl esters; FLUORAD FC-430, generally described as fluorinated alkyl esters; FLUORAD FC-431, generally described as fluorinated alkyl esters; and FLUORAD FC-170-C, which are generally described as fluorinated alkylpolyoxyethylene ethanols.

An example of a suitable cationic fluorosurfactant compound has the following structure: Cn 2n + iS02 HC3H6N + (CH3) 3l where n is about 8. This cationic fluorosurfactant is available under the tradename FLUORAD FC-135 from 3M. Another example of a suitable cationic fluorosurfactant is F3- (CF2) n-- (CH2) mSCH2CHOH-CH2-N + R1R2R3Cl ~ where: n is 5 to 9 and m is 2, and R1, R2 and R3 are -CH3. This cationic fluorosurfactant is available under the trade name ZONYL FSD (available from DuPont, described as 2-hydroxy-3- ((gamma-omega-perfluoro-C6-20_ alkyl) thio) -N, N, N-trimethyl-1-1-propyl ammonium chloride). Other cationic fluorosurfactants suitable for use in the present invention are also described in European Patent EP 866,115 by Leach and Niwata, incorporated herein by reference. The fluorosurfactant selected from the group of non-ionic fluorosurfactants, cationic fluorosurfactants and their mixtures may be present in amounts of 0.001 to 5% by weight, preferably 0.01 to 1% by weight and more preferably 0.01. at 0.5% by weight.

Some embodiments of the invention may comprise a nonionic surfactant. Basically all alkoxylated nonionic surfactants are suitable herein, for example, ethoxylated and propoxylated nonionic surfactants. The alkoxylated surfactants can be selected from the nonionic condensate classes of alkylphenols, nonionic ethoxylated alcohols, nonionic ethoxylated / propoxylated fatty alcohols, nonionic ethoxylated / propoxylated condensates with propylene glycol and nonionic ethoxylated condensation products with propylene oxide / ethylene diamine adducts. .

The condensation products of aliphatic alcohols with 1 to 25 moles of alkylene oxide, particularly ethylene oxide and / or propylene oxide are suitable for use herein. The alkyl chain of aliphatic alcohol may be straight or branched, primary or secondary and generally contains from 6 to 22 carbon atoms. Also suitable are the condensation products of alcohols having an alkyl group containing from 8 to 20 carbon atoms with 2 to 10 moles of ethylene oxide per mole of alcohol.

The polyhydroxy fatty acid amides suitable for use herein are those having the structural formula ## STR4 ## wherein: R1 is H, hydrocarbylCi-C4, 2-hydroxyethyl, 2-hydroxypropyl, ethoxy, propoxy or a mixture of these, for example, Ci-C4 alkyl, or Ci or C2 alkyl; and R2 is a C5-C31 hydrocarbyl, for example, straight chain C5-C19 alkyl or alkenyl, or straight-chain C9-Ci7 alkyl or alkenyl, or C11-C17 alkyl or alkenyl, or mixtures thereof and Z is a polyhydroxyhydrocarbyl which has a linear hydrocarbyl chain with at least 3 hydroxyls directly connected to the chain, or its alkoxylated derivative (eg, ethoxylated or propoxylated). Z can be derived from the reduction of a sugar in a reductive amination reaction, for example, Z is a glycityl.

Suitable fatty acid surfactants include those having the formula: R 1 CON (R 2) 2 wherein R 1 is an alkyl group containing from 7 to 21, or from 9 to 17 carbon atoms and each R 2 is selected from the group consisting of hydrogen , Ci-C4 alkyl, hydroxyalkyl Ci-C, and - (C2H 0) xH, where x is in the range of 1 to 3.

Alkylpolysaccharides suitable for use herein are disclosed in U.S. Patent No. 4,565,647 to Filling, incorporated herein by reference, having a hydrophobic group containing from 6 to 30 carbon atoms and a polysaccharide, for example, a polyglycoside, a hydrophilic group containing from 1.3 to 10 units of saccharides. The alkyl polyglycosides can have the formula: R20 (CnH2nO) t (glycosyl) x where R2 is selected from the group consisting of alkyl, alkylphenyl, hydroxyalkyl, hydroxyalkylphenyl and mixtures thereof where the alkyl groups contain from 10 to 18 carbon atoms; n is 2 or 3; t is from 0 to 10, and x is from 1.3 to 8. The glycosyl can be derived from glucose.

Other suitable nonionic surfactants are the safe food nonionic surfactants. Examples of safe food nonionic surfactants are the sucrose esters, such as sucrose cocoate available in Croda, and sorbitan esters, such as polyoxyethylene (20) sorbitan monooleate from J.T. Baker and polyoxyethylene (20) sorbitan monolaurate from Uniquema. Other examples of safe food nonionic surfactants are provided in the lists of those generally considered safe (GRAS), as described below.

In one embodiment, the compositions may specifically contain an alkyl polyglycoside ("APG") surfactant. Suitable alkyl polyglycoside surfactants are alkyl polysaccharides which are disclosed in U.S. Patent No. 5,776,872 to Giret et al; U.S. Patent No. 5,883,059 to Furman et al; U.S. Patent No. 5,883,062 to Addison et al; and U.S. Patent No. 5,906,973 to Ouzounis et al, which are incorporated by reference. Alkyl polyglycosides suitable for use herein are also disclosed in U.S. Patent No. 4,565,647 to Llenado (also incorporated by reference) which describes alkyl polyglucosides having a hydrophobic group containing from about 6 to about 30 carbon atoms. carbon, or from about 10 to about 16 carbon atoms and polysaccharides, for example, a polyglycoside, a hydrophilic group containing from about 1.3 to about 10, or from about 1.3 to about 3, or about 1 , 3 to about 2.7 units of saccharides. Optionally, there may be a polyalkylenoxide chain that is linked with the hydrophobic portion and the polysaccharide portion. A suitable alkylene oxide is ethylene oxide. Typical hydrophobic groups include alkyl, saturated or unsaturated, branched or unbranched groups containing from about 8 to about 18 or from about 10 to about 16 carbon atoms. The alkyl group may contain about 3 hydroxy groups and / or the polyalkylenoxide chain may contain up to about 10 or less than about 5 alkylenoxide portions. The suitable alkyl polysaccharides are octyl, nonyldecyl, undecyldecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, and octadecyl, di-, tri-, tetra-, penta-, and hexaglucosides, galactosides, lactosides, glucoses, fructosides, fructose and / or galactoses. Suitable mixtures include di, tri, tetra and pentaglucosides of coconut alkyl and tetra, penta and tallow alkyl hexagucosides.

Suitable alkyl polyglycosides (or alkyl polyglycosides) have the formula: R20 (CnH2n0) t (glucosyl) x wherein R2 is selected from the group consisting of alkyl, alkylphenyl, hydroxyalkyl, hydroxyalkylphenyl and mixtures thereof where the alkyl groups contain from about 10 to about 18 , preferably from about 12 to about 14 carbon atoms; n is about 2 or about 3, preferably about 2; t is from 0 to about 10, preferably 0; and x is from about 1.3 to about 10, preferably from about 1.3 to about 3, more preferably from about 1.3 to about 2.7. The glycosyl is preferably derived from glucose. To prepare these compounds, the alkylpolyethoxy alcohol or alcohol is first formed and then reacted with glucose or a glucose source to form the glucoside (linkage at position 1). The additional glycosyl units can then be linked between their position 1 and the preceding glycosyl units in position 2, 3, 4 and / or 6, preferably predominantly position 2.

A group of alkyl glycoside surfactants suitable for use in the practice of the present invention may be represented by formula I below: where R is a monovalent organic radical containing from about 6 to about 30 (preferably from about 8 to about 18) carbon atoms; R2 is a divalent hydrocarbon radical containing from about 2 to about 4 carbon atoms; Or it is an oxygen atom; and is a number that has an average value of about 0 to about -1 and is preferably 0; G is a portion that is derived from the reduction of a saccharide containing 5 or 6 carbon atoms; and x is a number having an average value of about 1 to 5 (preferably from 1.1 to 2); Z is O2M1, 02CR3, 0 (CH2), CO2M1, OSO3M1, or 0 (CH2) S03M1; R3 is (CH2) C02M1 or CH = CHC02M1; (with the proviso that Z can be 02 only if Z is found in place of a primary hydroxyl group where the carbon atom having the primary hydroxyl, --CH2OH, is oxidized to form a group --C02M1); b is a number from 0 to 3x + 1, preferably an average of 0.5 to 2 per glycosal group; p is 1 to 10, M1 is H + or an organic or inorganic cation, such as, for example, an alkali metal, ammonium, monoethanolamine, or calcium. As defined in formula I, R is generally the residue of a fatty alcohol having from about 8 to 30 or from 8 to 18 carbon atoms. Suitable alkyl glycosides include, for example, APG 325 (an alkylCg-Cupoliglycoside available from Cognis Corporation), APG 625 (an alkylCio-Ci6 polyglycoside available from Cognis Corporation), Dow TRITON CGI 10 (an alkylC8-Ci0 polyglycoside available from Dow Chemical C ' ompany), AG6202 (an alkyl-polyglycoside available from Akzo Nobel), GLUCOPON 425N (an alkyl-C-polyglycoside available from Cognis Corporation), GLUCOPON 215 (an alkyl-C8-Cio-polyglycoside available from Cognis Corporation), GLUCOPON-225 (an alkyl-C-C-polyglycoside available from Cognis Corporation) and ALKADET 150 (an alkylCe-Ciopolyglycoside available from Huntsman Corporation). The alkylCe-Ciopolyglycoside includes alkyl polyglucosides wherein the alkyl group is basically alkyl, basically alkyl, or a mixture of substantially C, and C alkyl. Also the. Short chain APG as C4 and / or C6 or their mixtures may be suitable for use with the present invention.

In one embodiment, the composition does not contain any enzyme, wax, resin, nonionic surfactant, chloride salts or chloride dioxide.

IX. Hydrotropes The composition may include one or more hydrotropes to solubilize the other components of the composition upon addition of water. When hydrotropic solubilizing materials are used, they include, but are not limited to, water-soluble salts of low molecular weight organic acids such as the alkali metal salts (sodium and / or potassium) of aromatic sulfonic acids. Specific exemplary materials include, but are not limited to, toluene sulfonate, eumeno sulfonate, xylene sulfonate, naphthalene sulfonate, methyl naphthalene sulfonate and combinations thereof.

The hydrotropes may be present at a level of from about 0.1% to about 25%, from about 0.1% to about 20%, from about 0.1% to about 15%, of about 0.1% to about 10%), from about 0.1% to about 5%.

X. Additional auxiliaries In some embodiments, the compositions may optionally contain one or more of the following auxiliaries: colorants, perfumes, sequestrants, anticorrosive agents, lubricants, binders, fillers, disintegrating aids, preservatives or desiccants. Other auxiliaries include, but are not limited to, acids, electrolytes, stabilizers, thickeners, defoamers, cloud point modifiers, spot repellents, odor controlling agents, brighteners, fluorescent whitening agents and solid processing aids. When binders are used they include, but are not limited to, celluloses, starches, gums and synthetic polymers. When solid processing aids are used they include, but are not limited to, flow aids, lubricants, antistatic and sliding agents. When electrolytes are used, they may include, but are not limited to, calcium, sodium, and potassium chloride. When thickeners are used, they include, but are not limited to, xanthan gum, calcium carbonate, cellulose, aluminum oxide, alginates, guar gum, methyl, ethyl, clays and / or propyl hydroxycelluloses. When defoamers are used, they include, but are not limited to, silicones, aminosilicones, silicone mixtures and / or silicone / hydrocarbon mixtures.

When preservatives are used, they include, but are not limited to, antimicrobials or antimicrobials, methyl, ethyl and propylparabens, phosphates such as trisodium phosphate, short chain organic acids (eg, acetic, lactic and / or glycolic acid), bisguanide compounds. (for example, DANTAGARD and / or GLYDANT) and / or short chain alcohols (for example, ethanol and / or isopropyl alcohol). Antimicrobials or antimicrobial agents include, but are not limited to, antimicrobial agents (including non-isothiazolone compounds) that include KATHON GC, a 5-chloro-2-methyl-4-isothiazolin-3-one, KATHON ICP, a 2- methyl-4-isothiazolin-3-one and a mixture of these and KATHON 886, a 5-chloro-2-methyl-4-isothiazolin-3-one, all available from Rohm and Haas Company; BRONOPOL, a 2-bromo-2-nitropropane 1.3 diol, from Boots Cómpany Ltd., PROXEL CRL, a propyl-p-hydroxybenzoate, from ICI 'PLC; NIPASOL M, an o-phenyl-phenol, Na + salt, from ipa Laboratories Ltd., DOWICIDE A, a 1,2-benzisothiazolin-3-one, from Dow Chemical Co. , and IRGASAN DP 200, a 2,, 4'-trichloro-2-hydroxydiphenylether, from Ciba-Geigy A.G.

XI. Forms and uses The compositions of the present invention can be used in the disinfection of dentures, although other uses of the composition (for example, a buccal elixir or disinfection in endodontics) are also contemplated. The composition of a layer of the present invention is preferably in the form of a substantially homogeneous tablet of a single layer, although it can alternatively take the form of a powder or granules. The present invention relates to the claims of the composition and methods for the use of the composition. Generally, the steps of the method for the use of the composition include contacting a specific surface (e.g., dentures) with the composition in water so as to clean the specific surface with the composition.

XII. And emplos By way of non-limitation, the following examples illustrate an exemplary implementation of the present invention: -Table 1 - Exemplary compositions 1 to 4 Table 1 - Exemplary compositions 1 to 4 The compositions in Table 1 were initially prepared as powders. The powders in the table above were prepared and dissolved in 150 mL of water to prepare a cleaning solution for dentures and dental instruments. All the powders showed effervescence and created foam to signal the cleaning dust. They also released the indicated amount of hypochlorous acid to disinfect and remove stains, plaque and biofilms. The pH of the cleaning solution was between pH 5.5 and pH 6.5.

Each of the powders in Table 1 was compressed into single-layer tablets to provide the desired weight per use. All the tablets were dissolved within 5 minutes with effervescence and foam. All of them released the target concentration of hypochlorous acid when they were added to 150 mL of water and presented a pH between 5.5 and 6.5.

Additional exemplary compositions 5 to 19 are described in Tables 2 to 4 below.

Table 2 - Exemplary compositions 5 to 9 ' Table 3 - Example compositions Without departing from the spirit and scope of the present invention, the person skilled in the art can make various changes and modifications to the invention to adapt it to the various uses and conditions. As such, these changes and modifications are suitable, equitable and intended to be made within the full equivalence range of the following claims.

It is noted that in relation to this date, the best method known to the applicant to carry out the aforementioned invention, is that which is clear from the present description of the invention.

Claims (20)

1. A solid composition of a layer comprising: a) a hypochlorite selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) a mej orator selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof; c) an acid selected from the group consisting of carboxylic acid, dicarboxylic acid, sulfonic acid, acid sulfate, acid phosphate and mixtures thereof; d) a water-soluble polymer selected from the group consisting of a polycarboxylate, sulfonated carboxylate, polysulfonate, polyvinylpyrrolidone, polypyridinium salt, polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; Y f) at least one hydrotrope; ' g) wherein the composition does not contain potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, carboxylic acids which also have one or more hydroxyl, amino, amido, imino, or imido; h) where the composition contains only one layer.

2. The composition of claim 1, wherein the hypochlorite is calcium hypochlorite and the calcium hypochlorite comprises less than 50% of the composition.

3. The composition of claim 2, wherein the acid comprises at least 30% of the composition.

4. The composition of claim 2, wherein the acid comprises at least 50% of the composition.

5. The composition of claim 3, wherein the acid is a dicarboxylic acid.

6. The composition of the claim. 5, wherein the water soluble polymer is a polycarboxylate and the polycarboxylate is selected from the group consisting of maleic acid, acrylic acid, methacrylic acid and mixtures thereof.

7. The composition of claim 6, wherein the hydrotrope is a salt selected from the group consisting of a toluene sulfonate, eumenal urt sulfonate, a xylene sulfonate, a naphthalene sulfonate, a methyl naphthalene sulfonate and mixtures thereof.

8. The composition of claim 7, wherein the composition does not contain enzymes, waxes, resins, nonionic surfactants, chloride salts or chloride dioxide.

9. A solid composition of a layer consisting essentially of: a) a hypochlorite selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) a mej orator selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof; c) an acid selected from the group consisting of a carboxylic acid, a dicarboxylic acid, a sulfonic acid, an acid sulfate, an acid phosphate and mixtures thereof; d) a water soluble polymer selected from the group consisting of a polycarboxylate, a sulfonated carboxylate, a polysulfonate, a polyvinylpyrrolidone, a polypyridinium salt, a polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; f) at least one hydrotrope; Y g) optionally, a combiner that is selected from the group consisting of a hydroxide, an oxide, a silicate, a phosphate, a borate and their mixtures; Y h) optionally, colorants, perfumes, sequestrants, anticorrosive agents, lubricants, binders, fillers, disintegration aids, preservatives, desiccants and their mixtures.

10. The composition of claim 9, wherein the composition does not contain any potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, carboxylic acids that also have a hydroxyl, amino, amido group , imino, or imido, enzymes, waxes, resins or nonionic surfactants.

11. The composition of claim 10, wherein the hypochlorite is calcium hypochlorite and the calcium hypochlorite comprises less than 50% of the composition.

12. The composition of claim 11, wherein the acid comprises at least 30% of the composition.

13. The composition of claim 12, wherein the acid is a dicarboxylic acid.

14. The composition of claim 13, wherein the water soluble polymer is a polycarboxylate and the polycarboxylate is selected from the group consisting of maleic acid, acrylic acid, methacrylic acid and mixtures thereof.

15. The composition of claim 14, wherein the hydrotrope is a salt selected from the group consisting of a toluene sulfonate, a eumeno sulfonate, a xylene sulfonate, a naphthalene sulfonate, a methyl naphthalene sulfonate, and mixtures thereof.

16. A solid composition of a layer consisting of: a) a hypochlorite selected from the group consisting of calcium hypochlorite, magnesium hypochlorite and mixtures thereof; b) an improver that is selected from the group consisting of carbonate, bicarbonate, sesquicarbonate and mixtures thereof; c) an acid that is selected from the group consisting of a carboxylic acid, a. dicarboxylic acid, a sulfonic acid, acid sulfate, acid phosphate and their mixtures; d) a water-soluble polymer selected from the group consisting of a polycarboxylate, a sulfonated carboxylate, a polysulfonate, a polyvinylpyrrolidone, a polypyridinium salt, a polyquaternary ammonium salt and mixtures thereof; e) at least one anionic surfactant; f) optionally, at least one hydrotrope; g) optionally, a combiner that is selected from the group consisting of a hydroxide, an oxide, a silicate, a phosphate, a borate and their mixtures; Y h) optionally, colorants, perfumes, sequestrants, anticorrosive agents, lubricants, binders, fillers, disintegration aids, preservatives, desiccants and their mixtures.

17. The composition of claim 16 ,. wherein the composition does not contain any potassium hypochlorite, sodium hypochlorite, lithium hypochlorite, N-halogenated compounds, peroxides, persulfates, hydantoins, isocyanurates, carboxylic acids that also have a hydroxyl, amino, amido, imino, or imido group, enzymes , waxes, resins or nonionic surfactants.

18. The composition of claim 17, wherein the acid comprises at least 30% of the composition.

19. The composition of claim 18, wherein the acid comprises at least 50% of the composition.

20. The composition of claim 19, wherein the acid is a dicarboxylic acid.