MX2012013167A - Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits. - Google Patents
Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits.Info
- Publication number
- MX2012013167A MX2012013167A MX2012013167A MX2012013167A MX2012013167A MX 2012013167 A MX2012013167 A MX 2012013167A MX 2012013167 A MX2012013167 A MX 2012013167A MX 2012013167 A MX2012013167 A MX 2012013167A MX 2012013167 A MX2012013167 A MX 2012013167A
- Authority
- MX
- Mexico
- Prior art keywords
- derivatives
- drug
- regulation
- inflammatory infiltrate
- prevention
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to the use of betanidine and its derivatives, betalains and their derivatives, betalamic acid and its derivatives, including the spatial configurations thereof, for the production of a drug for the treatment, prevention, regulation and control of nonalcoholic steatohepatitis, inflammatory infiltrate in liver, hepatic necrosis, fatty liver, alcoholic steatohepatitis, non-alcoholic fatty liver disease, alcoholic fatty liver disease, hepatitis, necrosis, acute inflammatory infiltrate, chronic inflammatory infiltrate, mixed inflammatory infiltrate, non-alcoholic fatty liver, alcoholic fatty liver, liver fibrosis, cirrhosis of the liver, ageing, fibrosis, brain edema, neuronal degeneration and pancreatitis; for the regulation of the mobilisation of intracellular lipids; for the treatment, prevention, regulation and control of inflammatory infiltrate in an autoimmune response, associated with an infection, in tumours, produced as a response to fatty acids and their der ivatives, associated with a trauma, associated with a parasitic disease, associated with chronic degenerative diseases, produced by an immune response to a non-infectious antigen; for the modification of the intracellular lipid composition, for the protection of nucleic acids from damage, for the healing of wounds. Its effect consists in inhibiting the presence of inflammatory infiltrate, inhibiting necrosis and in modifying the predominance of the lipid vesicle type, following administration. The drug can contain one or more betalains and any of their derivatives and betalamic acid and any of its derivatives, either alone or in multiple combinations. In addition, the drug can contain a combination of other pharmaceutical products. The drug can be administered using an administration route. The drug, which contains a betalain, betalamic acid or a derivative of one of these types of compounds and is intended for the treatment, prevention, regulation and control of the above-mentioned a ilments and the regulation and mobilisation of lipids, fatty acids and their derivatives, can be administered to any animal, including humans.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2012013167A MX2012013167A (en) | 2012-11-09 | 2012-11-09 | Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits. |
PCT/MX2013/000134 WO2014073946A2 (en) | 2012-11-09 | 2013-11-08 | Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2012013167A MX2012013167A (en) | 2012-11-09 | 2012-11-09 | Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012013167A true MX2012013167A (en) | 2014-05-22 |
Family
ID=50685283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012013167A MX2012013167A (en) | 2012-11-09 | 2012-11-09 | Use of betalains and derivatives thereof for the production of a drug for the treatment, prevention, regulation and control of hepatopathies, diseases with inflammatory infiltrate, necrosis and for the modificaiton of lipid deposits. |
Country Status (2)
Country | Link |
---|---|
MX (1) | MX2012013167A (en) |
WO (1) | WO2014073946A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114901826A (en) * | 2019-12-19 | 2022-08-12 | 森正之 | Method for synthesizing coronatine II, method for synthesizing betaxanthin, beta-amyloid polymerization inhibitor or Alzheimer's disease therapeutic or preventive agent, amyloid peptide aggregation inhibitor, and HIV-1 protease activity inhibitor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL119872A (en) * | 1996-12-19 | 2000-01-31 | Israel State | Pharmaceutical compositions containing antioxidant betalains and a method for their preparation |
JP4741206B2 (en) * | 2004-07-12 | 2011-08-03 | 日本甜菜製糖株式会社 | Composition for suppressing or reducing serum cholesterol elevation |
DE202005002324U1 (en) * | 2005-02-14 | 2006-06-22 | Treusch, Gernot | Pharmaceutical composition for the fight against cancer |
WO2010014839A1 (en) * | 2008-07-30 | 2010-02-04 | Vdf Futureceuticals, Inc. | Betalain compositions and uses thereof |
ES2349522B1 (en) * | 2009-05-05 | 2011-10-27 | Universidad De Murcia | PROCEDURE FOR OBTAINING BETALAMIC ACID AND USE OF IT. |
LV14588B (en) * | 2011-03-30 | 2012-12-20 | Inovatäŗvo Biomedicäŗnas Tehnoloä¢Iju Institåŗts, Sia | A composition for prevention of hepatic fatty steatosis |
-
2012
- 2012-11-09 MX MX2012013167A patent/MX2012013167A/en unknown
-
2013
- 2013-11-08 WO PCT/MX2013/000134 patent/WO2014073946A2/en active Application Filing
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114901826A (en) * | 2019-12-19 | 2022-08-12 | 森正之 | Method for synthesizing coronatine II, method for synthesizing betaxanthin, beta-amyloid polymerization inhibitor or Alzheimer's disease therapeutic or preventive agent, amyloid peptide aggregation inhibitor, and HIV-1 protease activity inhibitor |
Also Published As
Publication number | Publication date |
---|---|
WO2014073946A3 (en) | 2014-08-07 |
WO2014073946A2 (en) | 2014-05-15 |
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