MX2012011666A - Cluap1 peptides and vaccines including the same. - Google Patents
Cluap1 peptides and vaccines including the same.Info
- Publication number
- MX2012011666A MX2012011666A MX2012011666A MX2012011666A MX2012011666A MX 2012011666 A MX2012011666 A MX 2012011666A MX 2012011666 A MX2012011666 A MX 2012011666A MX 2012011666 A MX2012011666 A MX 2012011666A MX 2012011666 A MX2012011666 A MX 2012011666A
- Authority
- MX
- Mexico
- Prior art keywords
- peptides
- cluap1
- methods
- antigen
- inducing
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 101150041557 cluap1 gene Proteins 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 3
- 230000001939 inductive effect Effects 0.000 abstract 3
- 102100033538 Clusterin-associated protein 1 Human genes 0.000 abstract 2
- 101000945060 Homo sapiens Clusterin-associated protein 1 Proteins 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 230000005809 anti-tumor immunity Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940023041 peptide vaccine Drugs 0.000 abstract 1
- 230000002980 postoperative effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
Abstract
Peptide vaccines against cancer are described herein. In particular, epitope peptides derived from the CLUAP1 gene that elicit CTLs are provided. Antigen-presenting cells and isolated CTLs that target such peptides, as well as methods for inducing the antigen-presenting cell, or CTL are also provided. The present invention further provides pharmaceutical compositions containing as active ingredient peptides derived from CLUAP1 or polynucleotides encoding the peptides as active ingredients. Furthermore, the present invention provides methods for the treatment and/or prophylaxis (i.e., prevention) of cancers (tumors), and/or the prevention of postoperative recurrence thereof, as well as methods for inducing CTLs, methods for inducing anti-tumor immunity, using the peptides derived from CLUAP1, polynucleotides encoding the peptides, or antigen-presenting cells presenting the peptides, or the pharmaceutical compositions of the present invention.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32209910P | 2010-04-08 | 2010-04-08 | |
PCT/JP2010/006313 WO2011125139A1 (en) | 2010-04-08 | 2010-10-26 | Cluap1 peptides and vaccines including the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012011666A true MX2012011666A (en) | 2012-12-17 |
Family
ID=44762128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012011666A MX2012011666A (en) | 2010-04-08 | 2010-10-26 | Cluap1 peptides and vaccines including the same. |
Country Status (9)
Country | Link |
---|---|
JP (1) | JP2013523083A (en) |
KR (1) | KR20130043632A (en) |
AU (1) | AU2010350389A1 (en) |
BR (1) | BR112012025486A2 (en) |
CA (1) | CA2795423A1 (en) |
MX (1) | MX2012011666A (en) |
SG (1) | SG184468A1 (en) |
TW (1) | TW201134480A (en) |
WO (1) | WO2011125139A1 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3971769B2 (en) * | 2002-09-12 | 2007-09-05 | オンコセラピー・サイエンス株式会社 | KDR peptide and vaccine containing the same |
TW201000115A (en) * | 2008-06-11 | 2010-01-01 | Oncotherapy Science Inc | IQGAP3 epitope peptides and vaccines containing the same |
-
2010
- 2010-10-21 TW TW099135910A patent/TW201134480A/en unknown
- 2010-10-26 WO PCT/JP2010/006313 patent/WO2011125139A1/en active Application Filing
- 2010-10-26 SG SG2012074258A patent/SG184468A1/en unknown
- 2010-10-26 MX MX2012011666A patent/MX2012011666A/en not_active Application Discontinuation
- 2010-10-26 AU AU2010350389A patent/AU2010350389A1/en not_active Abandoned
- 2010-10-26 BR BR112012025486A patent/BR112012025486A2/en not_active IP Right Cessation
- 2010-10-26 CA CA2795423A patent/CA2795423A1/en not_active Abandoned
- 2010-10-26 JP JP2012544968A patent/JP2013523083A/en active Pending
- 2010-10-26 KR KR1020127029304A patent/KR20130043632A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW201134480A (en) | 2011-10-16 |
CA2795423A1 (en) | 2011-10-13 |
JP2013523083A (en) | 2013-06-17 |
KR20130043632A (en) | 2013-04-30 |
AU2010350389A1 (en) | 2012-10-25 |
WO2011125139A1 (en) | 2011-10-13 |
SG184468A1 (en) | 2012-11-29 |
BR112012025486A2 (en) | 2017-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |