MX2011012120A - Compositions and methods for immunodominant antigens of mycobacterium tuberculosis. - Google Patents

Compositions and methods for immunodominant antigens of mycobacterium tuberculosis.

Info

Publication number
MX2011012120A
MX2011012120A MX2011012120A MX2011012120A MX2011012120A MX 2011012120 A MX2011012120 A MX 2011012120A MX 2011012120 A MX2011012120 A MX 2011012120A MX 2011012120 A MX2011012120 A MX 2011012120A MX 2011012120 A MX2011012120 A MX 2011012120A
Authority
MX
Mexico
Prior art keywords
methods
compositions
mycobacterium tuberculosis
antigens
immunodominant antigens
Prior art date
Application number
MX2011012120A
Other languages
Spanish (es)
Other versions
MX344052B (en
Inventor
Philip Felgner
Maria Laura Gennaro
Original Assignee
Immport Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immport Therapeutics Inc filed Critical Immport Therapeutics Inc
Publication of MX2011012120A publication Critical patent/MX2011012120A/en
Publication of MX344052B publication Critical patent/MX344052B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and/or have a known association with a disease parameter.
MX2011012120A 2009-05-13 2009-05-13 Compositions and methods for immunodominant antigens of mycobacterium tuberculosis. MX344052B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/043822 WO2010132054A1 (en) 2009-05-13 2009-05-13 Compositions and methods for immunodominant antigens of mycobacterium tuberculosis

Publications (2)

Publication Number Publication Date
MX2011012120A true MX2011012120A (en) 2012-04-30
MX344052B MX344052B (en) 2016-12-02

Family

ID=41046910

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011012120A MX344052B (en) 2009-05-13 2009-05-13 Compositions and methods for immunodominant antigens of mycobacterium tuberculosis.
MX2015001830A MX359550B (en) 2009-05-13 2009-05-13 COMPOSITIONS and METHODS FOR IMMUNODOMINANT ANTIGENS OF MYCOBACTERIUM TUBERCULOSIS.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2015001830A MX359550B (en) 2009-05-13 2009-05-13 COMPOSITIONS and METHODS FOR IMMUNODOMINANT ANTIGENS OF MYCOBACTERIUM TUBERCULOSIS.

Country Status (4)

Country Link
EP (1) EP2429575A1 (en)
CN (1) CN102573896B (en)
MX (2) MX344052B (en)
WO (1) WO2010132054A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20100411A1 (en) * 2010-07-23 2012-01-24 Massimo Amicosante USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR THEIR CORRESPONDING NUCLEIC ACIDS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, RELATED TO DIAGNOSTIC AND VACCINE KIT.
CN102899334B (en) * 2012-10-29 2015-02-25 英诺特（唐山）生物技术有限公司 Mycobacterium tuberculosis recombinant protein and preparation method thereof
CN104419710B (en) * 2013-09-04 2017-06-16 上海市肺科医院 A kind of resistance new gene of mycobacterium tuberculosis and its application
CN103525829B (en) * 2013-09-16 2016-01-06 南京大学（苏州）高新技术研究院 A kind of preparation that can be used for the mycobacterium tuberculosis recombinant antigen of tuberculosis infection diagnosis
CN104805063A (en) * 2014-01-24 2015-07-29 中国人民解放军第三〇九医院 Mycobacterium tuberculosis latent infection related proteins, preparation and applications thereof
ES2962636T3 (en) * 2014-07-24 2024-03-20 Abbott Molecular Inc Methods for the detection and analysis of mycobacterium tuberculosis
ES2897933T3 (en) * 2014-08-15 2022-03-03 Oxford Immunotec Ltd Mycobacterium tuberculosis proteins
WO2016069612A2 (en) 2014-10-28 2016-05-06 Wisconsin Alumni Research Foundation Biomarkers for early diagnosis and differentiation of mycobacterial infection
EP3322483A4 (en) 2015-07-14 2019-01-02 Abbott Molecular Inc. Compositions and methods for identifying drug resistant tuberculosis
CN105037561B (en) * 2015-08-24 2018-07-24 华中科技大学 A kind of fusion protein CMFO and its application
CN105483214A (en) * 2015-11-24 2016-04-13 北京博瑞立安生物技术有限公司 Mycobacterium tuberculosis detection kit and application thereof
CN105572352B (en) * 2016-02-17 2017-07-28 遵义医学院附属医院 One group of tuberculosis latent infection diagnosis marker and application thereof
CN105675863B (en) * 2016-02-17 2017-10-20 遵义医学院附属医院 One group of multi-drug resistance tuberculosis diagnosis marker and application thereof
GB201700555D0 (en) 2017-01-12 2017-03-01 Peptinnovate Ltd Method for the treatment of a relapsing-remitting condition
JP7125060B2 (en) * 2017-01-19 2022-08-24 株式会社カネカ Primer sets, probes, kits and methods for detecting Mycobacterium kansasii
CN108096571B (en) * 2017-12-27 2021-08-17 河南科技大学 Tuberculosis polypeptide vaccine for preventing and treating tuberculosis and preparation method and application thereof
EP3847460A1 (en) 2018-09-07 2021-07-14 Wisconsin Alumni Research Foundation Biomarkers for early diagnosis and differentiation of mycobacterial infection
CN111948399A (en) * 2019-05-16 2020-11-17 广东体必康生物科技有限公司 Mycobacterium tuberculosis antigen protein Rv1705c and application of T cell epitope peptide thereof
CN110240636A (en) * 2019-06-04 2019-09-17 华中农业大学 Mycobacterium bovis molecular chaperone protein GroEL1 and its encoding gene and application
CN113278633B (en) * 2020-02-20 2022-10-28 北京蛋白质组研究中心 Mycobacterium tuberculosis H37Rv gene, and coding protein and application thereof
CN113549604A (en) * 2020-04-23 2021-10-26 中国医学科学院病原生物学研究所 Mycobacterium tuberculosis toxin antitoxin system Rv1045-Rv1044 and application thereof in preparation of antituberculosis drugs
CN112457410B (en) * 2020-11-05 2023-04-07 迈克生物股份有限公司 Antigen composition for detecting mycobacterium tuberculosis infection
CN112481402B (en) * 2020-12-29 2024-03-22 上海国际旅行卫生保健中心(上海海关口岸门诊部) Mycobacterium tuberculosis MLST typing detection primer group based on Sanger sequencing and application thereof
CN114099659A (en) * 2022-01-29 2022-03-01 中国疾病预防控制中心传染病预防控制所 Mycobacterium tuberculosis Rv0934 antigen protein, antigen epitope peptide thereof and application thereof
CN114807080B (en) * 2022-05-16 2024-06-07 上海交通大学 Methyltransferase for catalyzing methyl esterification of small-molecule carboxylic acid and application thereof
CN114989312B (en) * 2022-06-27 2023-07-21 安徽理工大学 Mycobacterium tuberculosis fusion protein DR2 and application thereof
CN116120411B (en) * 2022-12-07 2024-04-12 中国疾病预防控制中心传染病预防控制所 Mycobacterium tuberculosis protein antigen mixture, multi-antigen fusion protein, encoding gene and application
CN116063418B (en) * 2022-12-08 2024-04-12 中国疾病预防控制中心传染病预防控制所 Mycobacterium tuberculosis antigen composition EPPA 015, and preparation method and application thereof
CN117186247A (en) * 2023-11-07 2023-12-08 中国疾病预防控制中心传染病预防控制所 Mycobacterium tuberculosis multi-antigen fusion protein, encoding gene and application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294328B1 (en) * 1998-06-24 2001-09-25 The Institute For Genomic Research DNA sequences for strain analysis in Mycobacterium tuberculosis
US6892139B2 (en) * 1999-01-29 2005-05-10 The Regents Of The University Of California Determining the functions and interactions of proteins by comparative analysis
GB0500102D0 (en) * 2005-01-05 2005-02-09 Isis Innovation Method for generating a memory t cell response
EP2368568A1 (en) * 2006-11-01 2011-09-28 Immport Therapeutics, INC. Compositions and methods for immunodominant antigens
GB0716070D0 (en) * 2007-08-17 2007-09-26 Fusion Antibodies Ltd Diagnostic method and kit

Also Published As

Publication number Publication date
WO2010132054A1 (en) 2010-11-18
MX359550B (en) 2018-10-02
CN102573896A (en) 2012-07-11
EP2429575A1 (en) 2012-03-21
MX344052B (en) 2016-12-02
CN102573896B (en) 2016-05-11

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