MX2011010634A - Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa. - Google Patents

Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa.

Info

Publication number
MX2011010634A
MX2011010634A MX2011010634A MX2011010634A MX2011010634A MX 2011010634 A MX2011010634 A MX 2011010634A MX 2011010634 A MX2011010634 A MX 2011010634A MX 2011010634 A MX2011010634 A MX 2011010634A MX 2011010634 A MX2011010634 A MX 2011010634A
Authority
MX
Mexico
Prior art keywords
monoclonal antibody
human monoclonal
lipopolysaccarides
lps
antibody specific
Prior art date
Application number
MX2011010634A
Other languages
Spanish (es)
Inventor
Michael Rudolf
Holger Koch
Stefanie Fas
Original Assignee
Kenta Biotech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kenta Biotech Ag filed Critical Kenta Biotech Ag
Publication of MX2011010634A publication Critical patent/MX2011010634A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

The present invention relates to a human monoclonal antibody specific for the serotype IATS 01 of P. aeruginosa, and a hybridoma producing said monoclonal antibody. In addition, the present invention relates to pharmaceutical compositions comprising at least one antibody or at least one nucleic acid encoding said antibody.
MX2011010634A 2009-04-09 2010-04-06 Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa. MX2011010634A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09005245 2009-04-09
PCT/EP2010/002158 WO2010115606A1 (en) 2009-04-09 2010-04-06 Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa

Publications (1)

Publication Number Publication Date
MX2011010634A true MX2011010634A (en) 2012-03-06

Family

ID=40934847

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011010634A MX2011010634A (en) 2009-04-09 2010-04-06 Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa.

Country Status (10)

Country Link
US (1) US20120114657A1 (en)
EP (1) EP2417157A1 (en)
JP (1) JP2012523221A (en)
KR (1) KR20120016086A (en)
CN (1) CN102639562A (en)
BR (1) BRPI1013427A2 (en)
CA (1) CA2758081A1 (en)
IL (1) IL215549A0 (en)
MX (1) MX2011010634A (en)
WO (1) WO2010115606A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011102553A1 (en) * 2010-02-18 2011-08-25 Meiji Seika Kaisha, Ltd. Antibody against serotype i lipopolysaccharide of pseudomonas aeruginosa
MX349886B (en) * 2011-06-10 2017-08-17 Medimmune Llc Anti-pseudomonas psl binding molecules and uses thereof.
PT2776065T (en) 2011-11-07 2020-09-25 Medimmune Ltd Combination therapies using anti- pseudomonas psl and pcrv binding molecules
EP3374391B1 (en) 2015-11-10 2024-04-17 Visterra, Inc. Antibody molecule-drug conjugates that specifically binds to lipopolysaccharide and uses thereof
CN110431150A (en) 2017-01-18 2019-11-08 威特拉公司 Antibody molecule-drug conjugates and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4834975A (en) 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
US5955584A (en) * 1986-03-31 1999-09-21 Charter Ventures Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
ATE458006T1 (en) * 2003-05-14 2010-03-15 Kenta Biotech Ag HUMAN MONOCLONAL ANTIBODIES SPECIFIC TO LIPOPOLYSACCHARIDES (LPS) OF SEROTYPE IATS O6 OF PSEUDOMONAS AERUGINOSA
EP1690875A1 (en) * 2005-02-14 2006-08-16 Kenta Biotech AG Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype

Also Published As

Publication number Publication date
EP2417157A1 (en) 2012-02-15
BRPI1013427A2 (en) 2016-04-05
IL215549A0 (en) 2011-12-29
JP2012523221A (en) 2012-10-04
CN102639562A (en) 2012-08-15
WO2010115606A1 (en) 2010-10-14
US20120114657A1 (en) 2012-05-10
KR20120016086A (en) 2012-02-22
CA2758081A1 (en) 2010-10-14

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Legal Events

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