MX2009011461A - Compuestos de aminoalcoxiarilsulfonamida y su uso como ligandos de la 5-hidroxitriptamina6. - Google Patents
Compuestos de aminoalcoxiarilsulfonamida y su uso como ligandos de la 5-hidroxitriptamina6.Info
- Publication number
- MX2009011461A MX2009011461A MX2009011461A MX2009011461A MX2009011461A MX 2009011461 A MX2009011461 A MX 2009011461A MX 2009011461 A MX2009011461 A MX 2009011461A MX 2009011461 A MX2009011461 A MX 2009011461A MX 2009011461 A MX2009011461 A MX 2009011461A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- disorders
- pharmaceutically acceptable
- aminoalkoxy
- ligands
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
La presente invención se relaciona con compuestos novedosos de aminoalcoxiasilsulfonamida de la fórmula (I), sus derivados, sus estereoisómeros, sus sales farmacéuticamente aceptables y las composiciones farmacéuticamente aceptables que los contienen. La presente invención también se relaciona con un proceso para la preparación de los compuestos novedosos anteriores, sus derivados, sus estereoisómeros, sus sales farmacéuticamente aceptables y las composiciones farmacéuticamente aceptables que los contienen. Estos compuestos son útiles en el tratamiento de varios trastornos que están relacionados con las funciones del receptor de 5-HT6. De manera específica, los compuestos de esta invención también son útiles en el tratamiento de varios trastornos del CNS, trastornos hematológicos, trastornos de la alimentación, enfermedades asociadas con el dolor, enfermedades respiratorias, trastornos genitourológicos, enfermedades cardiovasculares y cáncer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN940CH2007 | 2007-05-03 | ||
PCT/IN2008/000247 WO2008136017A1 (en) | 2007-05-03 | 2008-04-15 | Aminoalkoxy aryl sulfonamide compounds and their use as 5-ht6 ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009011461A true MX2009011461A (es) | 2009-11-10 |
Family
ID=39743760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009011461A MX2009011461A (es) | 2007-05-03 | 2008-04-15 | Compuestos de aminoalcoxiarilsulfonamida y su uso como ligandos de la 5-hidroxitriptamina6. |
Country Status (21)
Country | Link |
---|---|
US (1) | US8003670B2 (es) |
EP (1) | EP2155674B1 (es) |
JP (1) | JP5139512B2 (es) |
KR (1) | KR101162482B1 (es) |
CN (1) | CN101675032B (es) |
AT (1) | ATE513810T1 (es) |
AU (1) | AU2008246947B2 (es) |
BR (1) | BRPI0809873A2 (es) |
CA (1) | CA2683124C (es) |
CY (1) | CY1111836T1 (es) |
DK (1) | DK2155674T3 (es) |
EA (1) | EA016594B1 (es) |
ES (1) | ES2366496T3 (es) |
HK (1) | HK1138264A1 (es) |
HR (1) | HRP20110530T1 (es) |
IL (1) | IL201491A (es) |
MX (1) | MX2009011461A (es) |
NZ (1) | NZ581580A (es) |
SI (1) | SI2155674T1 (es) |
WO (1) | WO2008136017A1 (es) |
ZA (1) | ZA200907015B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101338954B1 (ko) | 2012-02-13 | 2013-12-09 | 주식회사 평산 | 링 압연 공정을 이용한 비대칭 단면을 가지는 제품의 성형 장치 및 성형 방법 |
KR101337003B1 (ko) | 2012-02-13 | 2013-12-04 | 주식회사 평산 | 링 압연 공법을 이용한 풍력 타워용 플랜지 제조방법 |
EP3027613B1 (en) | 2013-07-25 | 2018-03-28 | Uniwersytet Jagiellonski | Pyrroloquinoline derivatives as 5-ht6 antagonists, preparation method and use thereof |
JP6454346B2 (ja) | 2013-12-20 | 2019-01-16 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. | 芳香族複素環式化合物及び医薬におけるその応用 |
EP3166924B1 (en) | 2014-07-08 | 2019-02-20 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
WO2019180176A1 (en) | 2018-03-21 | 2019-09-26 | Spherium Biomed, S.L. | Composition for the treatment of schizophrenia and/or psychosis |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
BR9810991A (pt) | 1997-07-11 | 2000-08-08 | Smithkline Beecham Plc | Novos compostos |
GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
ES2291024T4 (es) | 1999-04-21 | 2009-03-01 | Nps Allelix Corp. | Compuestos de piperidina-indol con afinidad con 5-ht6. |
GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
CN1222511C (zh) | 2000-11-02 | 2005-10-12 | 惠氏公司 | 作为5-羟色胺-6配体的1-芳基-或1-烷基磺酰基-杂环基吲哚 |
WO2002060871A2 (en) | 2001-01-30 | 2002-08-08 | Eli Lilly And Company | Benzenesulfonic acid indol-5-yl esters as antagonists of the 5-ht6 receptor |
CA2438099A1 (en) | 2001-02-08 | 2002-12-12 | Memory Pharmaceuticals Corporation | Trifluoromethylpurines as phosphodiesterase 4 inhibitors |
DE60218037T2 (de) | 2001-06-07 | 2007-08-23 | F. Hoffmann-La Roche Ag | Neue indolderivate mit affinität zum 5-ht6-rezeptor |
JP2005527463A (ja) | 2001-08-07 | 2005-09-15 | スミスクライン ビーチャム パブリック リミテッド カンパニー | Cns疾患を治療するための5−ht6受容体アフィニティーを有する3−アリールスルホニル−7−ピペラジニル−インドール、−ベンゾフランおよび−ベンゾチオフェン |
WO2003065046A2 (en) | 2002-02-01 | 2003-08-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
US20070270432A1 (en) | 2002-02-05 | 2007-11-22 | James Hagan | Novel Method |
DK1497266T3 (da) | 2002-03-27 | 2008-10-06 | Glaxo Group Ltd | Quinolinderivater og deres anvendelse som 5HT6-ligander |
WO2004048331A1 (en) | 2002-11-28 | 2004-06-10 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
KR100776118B1 (ko) * | 2002-11-28 | 2007-11-15 | 수벤 라이프 사이언시스 리미티드 | 엔-아릴술포닐-3-아미노알콕시인돌 |
KR100818508B1 (ko) | 2002-11-28 | 2008-03-31 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물 |
NZ540841A (en) | 2002-12-18 | 2008-08-29 | Suven Life Sciences Ltd | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
CA2508275A1 (en) * | 2002-12-20 | 2004-07-08 | Cancer Research Technology Limited | 4-(1-(sulfonyl)-1h-indol-2-yl)-4-(hydroxy)-cyclohexa-2,5-dienone compounds and analogs thereof as therapeutic agents |
ES2222828B1 (es) | 2003-07-30 | 2006-04-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de 1-sulfonilindoles, su preparacion y su aplicacion como medicamentos. |
WO2006038594A1 (ja) * | 2004-10-04 | 2006-04-13 | Ono Pharmaceutical Co., Ltd. | N型カルシウムチャネル阻害薬 |
MX2008002018A (es) | 2005-08-12 | 2008-03-27 | Suven Life Sciences Ltd | Derivados de aminoaril sulfonamida como ligandos funcionales del 5-ht6. |
-
2008
- 2008-04-15 DK DK08763731.0T patent/DK2155674T3/da active
- 2008-04-15 US US12/598,616 patent/US8003670B2/en not_active Expired - Fee Related
- 2008-04-15 NZ NZ581580A patent/NZ581580A/en not_active IP Right Cessation
- 2008-04-15 AU AU2008246947A patent/AU2008246947B2/en not_active Ceased
- 2008-04-15 CA CA2683124A patent/CA2683124C/en not_active Expired - Fee Related
- 2008-04-15 BR BRPI0809873A patent/BRPI0809873A2/pt not_active IP Right Cessation
- 2008-04-15 SI SI200830379T patent/SI2155674T1/sl unknown
- 2008-04-15 EP EP08763731A patent/EP2155674B1/en active Active
- 2008-04-15 KR KR1020097025160A patent/KR101162482B1/ko active IP Right Grant
- 2008-04-15 WO PCT/IN2008/000247 patent/WO2008136017A1/en active Application Filing
- 2008-04-15 JP JP2010505014A patent/JP5139512B2/ja not_active Expired - Fee Related
- 2008-04-15 ES ES08763731T patent/ES2366496T3/es active Active
- 2008-04-15 CN CN2008800144405A patent/CN101675032B/zh not_active Expired - Fee Related
- 2008-04-15 MX MX2009011461A patent/MX2009011461A/es active IP Right Grant
- 2008-04-15 AT AT08763731T patent/ATE513810T1/de active
- 2008-04-15 EA EA200971017A patent/EA016594B1/ru not_active IP Right Cessation
-
2009
- 2009-10-08 ZA ZA200907015A patent/ZA200907015B/xx unknown
- 2009-10-13 IL IL201491A patent/IL201491A/en active IP Right Grant
-
2010
- 2010-04-07 HK HK10103434.6A patent/HK1138264A1/xx not_active IP Right Cessation
-
2011
- 2011-07-14 HR HR20110530T patent/HRP20110530T1/hr unknown
- 2011-09-14 CY CY20111100881T patent/CY1111836T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR101162482B1 (ko) | 2012-07-03 |
ES2366496T3 (es) | 2011-10-20 |
AU2008246947B2 (en) | 2011-03-31 |
HRP20110530T1 (hr) | 2011-09-30 |
IL201491A (en) | 2015-04-30 |
EP2155674B1 (en) | 2011-06-22 |
US20100087484A1 (en) | 2010-04-08 |
BRPI0809873A2 (pt) | 2018-11-13 |
IL201491A0 (en) | 2010-05-31 |
JP2010526057A (ja) | 2010-07-29 |
CY1111836T1 (el) | 2015-10-07 |
WO2008136017A1 (en) | 2008-11-13 |
EP2155674A1 (en) | 2010-02-24 |
EA016594B1 (ru) | 2012-06-29 |
CA2683124C (en) | 2012-09-25 |
EA200971017A1 (ru) | 2010-04-30 |
US8003670B2 (en) | 2011-08-23 |
KR20100007954A (ko) | 2010-01-22 |
HK1138264A1 (en) | 2010-08-20 |
JP5139512B2 (ja) | 2013-02-06 |
ATE513810T1 (de) | 2011-07-15 |
CN101675032B (zh) | 2012-10-31 |
DK2155674T3 (da) | 2011-09-26 |
AU2008246947A1 (en) | 2008-11-13 |
ZA200907015B (en) | 2010-07-28 |
CN101675032A (zh) | 2010-03-17 |
NZ581580A (en) | 2011-03-31 |
CA2683124A1 (en) | 2008-11-13 |
SI2155674T1 (sl) | 2011-10-28 |
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