MX2008006711A - Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators. - Google Patents
Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators.Info
- Publication number
- MX2008006711A MX2008006711A MX2008006711A MX2008006711A MX2008006711A MX 2008006711 A MX2008006711 A MX 2008006711A MX 2008006711 A MX2008006711 A MX 2008006711A MX 2008006711 A MX2008006711 A MX 2008006711A MX 2008006711 A MX2008006711 A MX 2008006711A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- identifying
- methods
- optimizing
- synthesizing
- Prior art date
Links
Abstract
This invention relates to methods of identifying, synthesizing, optimizing and profiling compounds that are inhibitors or activators of proteins, both naturally occurring endogenous proteins as well as certain variant forms of endogenous proteins, and novel methods of identifying such variants. The method accelerates the identification and development of compounds as potential therapeutically effective drugs by simplifying the pharmaceutical discovery and creation process through improvements in hit identification, lead optimization, biological profiling, and rapid elimination of toxic compounds. Implementation results in overall cost, reductions in the drug discovery process resulting from the corresponding increases in efficiency.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73947605P | 2005-11-23 | 2005-11-23 | |
US73947705P | 2005-11-23 | 2005-11-23 | |
US74176705P | 2005-12-02 | 2005-12-02 | |
US75103005P | 2005-12-16 | 2005-12-16 | |
US78310606P | 2006-03-13 | 2006-03-13 | |
US78581706P | 2006-03-23 | 2006-03-23 | |
US78590406P | 2006-03-23 | 2006-03-23 | |
US78937906P | 2006-04-04 | 2006-04-04 | |
US11/633,890 US20070129179A1 (en) | 2005-12-05 | 2006-08-29 | Handheld electronic caddy scorekeeping device for a golfer |
PCT/US2006/045394 WO2007062213A2 (en) | 2005-11-23 | 2006-11-24 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008006711A true MX2008006711A (en) | 2008-10-20 |
Family
ID=40941304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008006711A MX2008006711A (en) | 2005-11-23 | 2006-11-24 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX2008006711A (en) |
-
2006
- 2006-11-24 MX MX2008006711A patent/MX2008006711A/en active IP Right Grant
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO2017019I2 (en) | Enzalutamide or a pharmaceutically acceptable salt thereof | |
EA200702048A1 (en) | PHARMACOKINETICALLY IMPROVED COMPOUNDS | |
Mandemaker et al. | DNA damage‐induced replication stress results in PA 200‐proteasome‐mediated degradation of acetylated histones | |
MY151036A (en) | Synthesis of (r)-n-methylnaltrexone | |
EA200801571A1 (en) | COMPOSITIONS CONTAINING CTL4-IG MOLECULES AND METHODS FOR THEIR RECEPTION | |
DE602004025101D1 (en) | HUMAN ANTI-HUMANE CD3 BONDING MOLECULES | |
CY1111896T1 (en) | NON-ADMINISTRATIVE PHARMACEUTICAL FORMS OF ORAL INCLUSIVE INCLUSIVE ANALYSIS | |
NO20082559L (en) | Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and methods for using anti-PTK7 antibodies | |
NO20064893L (en) | Synthesis of Boronic Acid Esters and Acid Compounds | |
EA200800909A1 (en) | OBTAINING PREGABALIN AND RELATED COMPOUNDS | |
TW200716646A (en) | (S)-N-methylnaltrexone | |
MX2007006640A (en) | Biomarkers for pre-selection of patients for anti-igf1r therapy. | |
EA200870021A1 (en) | HUMAN MONOCLONAL ANTIBODIES TO FUKOZIL-GM1 AND METHODS OF APPLICATION OF ANTI-FUKOSIL-GM1 ANTIBODIES | |
MX2012004258A (en) | Inhibitors of bruton's tyrosine kinase. | |
EA201070247A1 (en) | PROTEAS INHIBITORS | |
NO20053112L (en) | Peptides that target tumor and endothelial cells, compositions and uses thereof. | |
MA27880A1 (en) | TETRAHYDROCARBAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | |
MY140840A (en) | Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals | |
WO2003076592A3 (en) | Novel method for delivery and intracellular synthesis of sirna molecules | |
EA200701979A1 (en) | METHOD FOR OBTAINING OPIOID MODULATORS | |
EA200702193A1 (en) | GLYCOSILIZATION BELKOV | |
EA201390156A1 (en) | PRODUCTION OF INTER-ALPHA INHIBITOR PROTEINS (IaIp) FROM PLASMA | |
IL176479A0 (en) | Methods and compositions for identifying rna-binding proteins | |
TW200716132A (en) | Novel chemical compounds | |
NO20060535L (en) | Aztreonam-L-lysine and methods for preparing it |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |