MX2007006601A - Uso de compuesto que activa un receptor de vitamina d para reducir la hiperplasia intima, proliferacion de celulas de musculo liso y restenosis en mamiferos. - Google Patents

Uso de compuesto que activa un receptor de vitamina d para reducir la hiperplasia intima, proliferacion de celulas de musculo liso y restenosis en mamiferos.

Info

Publication number
MX2007006601A
MX2007006601A MX2007006601A MX2007006601A MX2007006601A MX 2007006601 A MX2007006601 A MX 2007006601A MX 2007006601 A MX2007006601 A MX 2007006601A MX 2007006601 A MX2007006601 A MX 2007006601A MX 2007006601 A MX2007006601 A MX 2007006601A
Authority
MX
Mexico
Prior art keywords
restenosis
mammals
methods
cell proliferation
muscle cell
Prior art date
Application number
MX2007006601A
Other languages
English (en)
Inventor
Jinshyun Ruth R Wu-Wong
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2007006601A publication Critical patent/MX2007006601A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5929,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion se refiere al uso de un compuesto que activa un receptor de vitamina D, preferiblemente 1,25-dihidroxivitamina D3 o 19-nor-1alfa, 25-dihidroxivitamina D2, para reducir la proliferacion de celulas de musculo pequeno, restenosis o hiperplasia intima en mamiferos.
MX2007006601A 2004-12-02 2005-12-01 Uso de compuesto que activa un receptor de vitamina d para reducir la hiperplasia intima, proliferacion de celulas de musculo liso y restenosis en mamiferos. MX2007006601A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63255504P 2004-12-02 2004-12-02
PCT/US2005/043904 WO2006060765A2 (en) 2004-12-02 2005-12-01 Use of a compound that activates a vitamin d receptor for reducing intimal hyperplasia, smooth muscle cell proliferation and restenosis in mammals

Publications (1)

Publication Number Publication Date
MX2007006601A true MX2007006601A (es) 2007-06-19

Family

ID=36282871

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006601A MX2007006601A (es) 2004-12-02 2005-12-01 Uso de compuesto que activa un receptor de vitamina d para reducir la hiperplasia intima, proliferacion de celulas de musculo liso y restenosis en mamiferos.

Country Status (6)

Country Link
US (1) US20070134286A1 (es)
EP (1) EP1830826A2 (es)
JP (1) JP2008521935A (es)
CA (1) CA2588453A1 (es)
MX (1) MX2007006601A (es)
WO (1) WO2006060765A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9388427B2 (en) * 2002-12-02 2016-07-12 Biovec, Llc In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6011421A (ja) * 1983-06-30 1985-01-21 Kureha Chem Ind Co Ltd 血中脂質降下剤
JPS6045516A (ja) * 1983-08-02 1985-03-12 Kureha Chem Ind Co Ltd 1α―ヒドロキシビタミンD3類を含有することを特徴とする抗炎症解熱鎮痛剤
WO2000010552A2 (en) * 1998-08-24 2000-03-02 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
EP1270026A1 (en) * 2001-06-22 2003-01-02 Erik Andersen Stents comprising vitamin D analogues for restenosis inhibition
CA2524026A1 (en) * 2003-04-30 2004-11-18 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
EP1631297A4 (en) * 2003-06-11 2007-09-05 Novacea Inc TREATMENT OF IMMUNOSTIC DISEASES WITH ACTIVE VITAMIN D COMPOUNDS ALONE OR IN COMBINATION WITH OTHER THERAPEUTICS
US20050209203A1 (en) * 2003-07-30 2005-09-22 Jin Tian Use of vitamin Ds or vitamin D analogs to treat cardiovascular disease
KR20070038460A (ko) * 2004-05-10 2007-04-10 노바세아, 인크. 활성 비타민 디(d) 화합물을 이용한 동맥 재협착의 예방
AU2005289664A1 (en) * 2004-09-24 2006-04-06 Bioxell S.P.A. 20-cycloalkyl,26,27-alkyl/haloalkyl vitamin D3 compounds and methods of use thereof

Also Published As

Publication number Publication date
WO2006060765A3 (en) 2007-01-04
EP1830826A2 (en) 2007-09-12
CA2588453A1 (en) 2006-06-08
JP2008521935A (ja) 2008-06-26
WO2006060765A2 (en) 2006-06-08
US20070134286A1 (en) 2007-06-14

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal