MD4370C1 - 11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties - Google Patents

11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties

Info

Publication number
MD4370C1
MD4370C1 MDA20150024A MD20150024A MD4370C1 MD 4370 C1 MD4370 C1 MD 4370C1 MD A20150024 A MDA20150024 A MD A20150024A MD 20150024 A MD20150024 A MD 20150024A MD 4370 C1 MD4370 C1 MD 4370C1
Authority
MD
Moldova
Prior art keywords
pyridazonyl
drim
tolyl
diene
bis
Prior art date
Application number
MDA20150024A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4370B1 (en
Inventor
Акулина АРЫКУ
Ионел МАНГАЛАДЖИУ
Александру ЧОКЫРЛАН
Лидия ЛУНГУ
Гёргицэ ЗБЫНЧОГ
Николета ВОРНИКУ
Original Assignee
Институт Химии Академии Наук Молдовы
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Химии Академии Наук Молдовы filed Critical Институт Химии Академии Наук Молдовы
Priority to MDA20150024A priority Critical patent/MD4370C1/en
Publication of MD4370B1 publication Critical patent/MD4370B1/en
Publication of MD4370C1 publication Critical patent/MD4370C1/en

Links

Abstract

The invention relates to the field of chemistry and medicine, namely to the synthesis of a new compound with hybrid terpenic and azaheterocyclic skeleton, which may be used in medicine as an antifungal and antibacterial agent.According to the invention, the compound 11,12-bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one, which exhibits antifungal and antibacterial properties is claimed.
MDA20150024A 2015-03-05 2015-03-05 11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties MD4370C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20150024A MD4370C1 (en) 2015-03-05 2015-03-05 11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20150024A MD4370C1 (en) 2015-03-05 2015-03-05 11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties

Publications (2)

Publication Number Publication Date
MD4370B1 MD4370B1 (en) 2015-09-30
MD4370C1 true MD4370C1 (en) 2016-04-30

Family

ID=54207225

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20150024A MD4370C1 (en) 2015-03-05 2015-03-05 11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties

Country Status (1)

Country Link
MD (1) MD4370C1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3358F1 (en) * 2006-07-14 2007-07-31 Institutul De Chimie Al Academiei De Stiinte A Moldovei 12-Hydroperoxy-8alpha,12-epoxy-11-bishomodrimane for use in treating mycotic infections
US20140135404A1 (en) * 2011-07-21 2014-05-15 Kansas State University Research Foundation Sesquiterpenes for antifungal applications
MD4326B1 (en) * 2013-10-22 2015-02-28 Institutul De Chimie Al Academiei De Ştiinţe A Moldovei N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4327B1 (en) * 2013-10-22 2015-02-28 Institutul De Chimie Al Academiei De Ştiinţe A Moldovei N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3358F1 (en) * 2006-07-14 2007-07-31 Institutul De Chimie Al Academiei De Stiinte A Moldovei 12-Hydroperoxy-8alpha,12-epoxy-11-bishomodrimane for use in treating mycotic infections
US20140135404A1 (en) * 2011-07-21 2014-05-15 Kansas State University Research Foundation Sesquiterpenes for antifungal applications
MD4326B1 (en) * 2013-10-22 2015-02-28 Institutul De Chimie Al Academiei De Ştiinţe A Moldovei N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4327B1 (en) * 2013-10-22 2015-02-28 Institutul De Chimie Al Academiei De Ştiinţe A Moldovei N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Desnos-Ollivier M., Dromer F., Dannaoui E. Detection of caspofungin resistance in Candida spp. by Etest. Journal of Clinical Microbiology, 2008, vol. 46, nr. 7, p. 2389-2392 *
Kuchkova K., Aricu A., Secara E., Barba A., Vlad P., Ungur N., Tuchilus C., Shova S., Zbancioc Gh., Mangalagiu I. Design, synthesis, and antimicrobial activity of some novel homodrimane sesquiterpenoids with diazine skeleton. Medicinal Chemistry Research, 2014, vol. 23, nr. 3, p. 1559-1568 *
Van den Broek P.J., Buys L.F., Van den Barselaar M.T., Leijh P.C., Van Furth R. Influence of human monocytes on the antibacterial activity of kanamycin and gentamicin for Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 1986, vol. 29, nr. 6, p. 1032-1039 *

Also Published As

Publication number Publication date
MD4370B1 (en) 2015-09-30

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees