MD176C2 - The method of obtaining derivatives 1,2,5,6 - tetrahydropiridine-3 carboxy aldehidoxime or their hydrochlorids - Google Patents
The method of obtaining derivatives 1,2,5,6 - tetrahydropiridine-3 carboxy aldehidoxime or their hydrochloridsInfo
- Publication number
- MD176C2 MD176C2 MD94-0266A MD940266A MD176C2 MD 176 C2 MD176 C2 MD 176C2 MD 940266 A MD940266 A MD 940266A MD 176 C2 MD176 C2 MD 176C2
- Authority
- MD
- Moldova
- Prior art keywords
- formula
- compound
- alkyl
- obtaining
- mentioned values
- Prior art date
Links
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to heterociclic compounds, particularly to obtaining their derivatives 1,2,5,6-tetrahydropiridin-3 - carboxyldehidoxim with the formula (1)NOR2 = CH-C=CH-CH2-CH2 N(R1)-CH2in which R1 represents H or methyl, R2 represents C1-C3 linear alkyl or saturated branched out, acetylordimethyl aminoethil, or hidrochlor with a colinomimetic activity.The aim of the invention is to trace out new compounels more active from the mentioned abova group.The obtaining of the products with special destination is achieved by the reaction of hydrochlor. Compound with the formula (II) CHO-C=CH-CH2-CH2-N(R1-CH2) in which R1 has the above mentioned values with hidrochlor compound with the formula (III) NH2OR2 a in which R2 represents H, C1-C3 alkyl or saturated, C2-C4-alkyl linear or unsaturated branched out.The compound with the formula NOR2 a = CH-CH-CH2-CH2-N(R1)-CH2 in which R1 and R2 a have the mentioned values, separated in a free form or in the form of hydrochlor optionally when R2a represents H the compound with the formula IA is treated with the compount R2 b Hal, in which R2b represents acetyl or dimetyl aminoethyl. Hal represents halogene. The resultant compound with the formula (Ib).NOR2b = CH-C=CH-CH2-CH2-N(R1)-CH2 in which R1 and R2d have the mentioned values are separating in a free from or in the form of hydroclor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19565/86A IT1191667B (en) | 1986-02-27 | 1986-02-27 | 1,2,5,6-TETRAIDROPIRIDIN-3-CARBOXALDEHYDE OXY DERIVATIVES, THEIR PREPARATION PROCEDURE AND THEIR APPLICATION AS DRUGS |
| SU4202171A SU1498387A3 (en) | 1986-02-27 | 1987-02-26 | Method of producing derivatives of 1,2,5,6-tetrahydropyridine-3-carboxal-dehydroxym or their hydrochlorides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD176B1 MD176B1 (en) | 1995-03-31 |
| MD176C2 true MD176C2 (en) | 1995-07-31 |
Family
ID=26327213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0266A MD176C2 (en) | 1986-02-27 | 1994-09-08 | The method of obtaining derivatives 1,2,5,6 - tetrahydropiridine-3 carboxy aldehidoxime or their hydrochlorids |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD176C2 (en) |
-
1994
- 1994-09-08 MD MD94-0266A patent/MD176C2/en active IP Right Grant
Non-Patent Citations (1)
| Title |
|---|
| Каррер П. Курс органической химии. М., Госхимиздат, 1960, с.204. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD176B1 (en) | 1995-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE215078T1 (en) | IMPROVED METHOD FOR PRODUCING PROTECTED 3,4-DIHYDROXYBUTURIC ACID ESTERS | |
| ATE7492T1 (en) | PROCESS FOR THE PREPARATION OF 4-AMINOCHLOROQUINOLINES. | |
| MX165509B (en) | A MULTISILAN CONTAINING TRIAZINE RING AND METHOD FOR PREPARING IT | |
| YU197389A (en) | Process for preparing 7-substituted-hept-6-enoic and heptanoic acids and their derivatives and intermediates | |
| GB2185252B (en) | Triazole derivatives | |
| FI912637A0 (en) | LIVSMEDEL OCH FODER. | |
| PL257730A1 (en) | Insecticide | |
| KR920016420A (en) | Method for preparing substituted tetrahydropyridine | |
| UA7046A1 (en) | METHOD OF OBTAINING CYCLOPROPANE DERIVATIVES | |
| ES2004141A6 (en) | 1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs. | |
| ES8506651A1 (en) | Substituted phenylalkyl(piperazinyl or homopiperazinyl)-propyl-(ureas or thioureas). | |
| MD176C2 (en) | The method of obtaining derivatives 1,2,5,6 - tetrahydropiridine-3 carboxy aldehidoxime or their hydrochlorids | |
| KR850000421A (en) | Method for preparing benzothiazepine derivative | |
| KR840000530A (en) | Method for preparing new benzotriazole | |
| KR870003107A (en) | Method for preparing chianthine derivative | |
| DE69106386D1 (en) | Oxysulfonylcarbamate. | |
| ES2029830T3 (en) | A PROCEDURE FOR PREPARING A DERIVATIVE OF 6-CETOPROSTAGLANDINA E1. | |
| DE3462884D1 (en) | Preparation of phenyl alanines by hydrogenation of phenyl serines | |
| GB9119281D0 (en) | Compound use and preparation | |
| ES8301931A1 (en) | Imidazoles. | |
| BR8603787A (en) | HETEROCYCLICAL COMPOUNDS, AND, THE PROCESS OF ITS PREPARATION AND APPLICATION | |
| KR890002011A (en) | 5-halogeno-6-amino-nicotinic acid halide. Method of manufacture and use thereof | |
| ES2157679T3 (en) | PROCEDURE TO PREPARE A 2-CYANOBIFENYL COMPOUND. | |
| KR900006295A (en) | Halogeno-4-methylpyrazoles and preparation method thereof | |
| ATE217311T1 (en) | PURINE DERIVATIVES CONTAINING CYCLOPROPANCYCLUS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20070225 |