MA71255A - Composés pour le traitement de l'ataxie spinocérébelleuse de type 3 - Google Patents

Composés pour le traitement de l'ataxie spinocérébelleuse de type 3

Info

Publication number
MA71255A
MA71255A MA71255A MA71255A MA71255A MA 71255 A MA71255 A MA 71255A MA 71255 A MA71255 A MA 71255A MA 71255 A MA71255 A MA 71255A MA 71255 A MA71255 A MA 71255A
Authority
MA
Morocco
Prior art keywords
compounds
treatment
spinocerebellar ataxia
ataxia type
type
Prior art date
Application number
MA71255A
Other languages
English (en)
Inventor
Jana Narasimhan
Nanjing Zhang
Xiaoyan Zhang
Anuradha Bhattacharyya
Guangming Chen
Yao JIANG
Matthew G. Woll
Michael A. Arnold
James R. ANNAND
Gayan Mirihana ARACHCHILAGE
Jackie CHIU
Gaurav Dahiya
Arun Raj KIZHAKKAYIL MANGADAN
Christie Morrill
Stephen E. MOTIKA
Original Assignee
Ptc Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics, Inc. filed Critical Ptc Therapeutics, Inc.
Publication of MA71255A publication Critical patent/MA71255A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA71255A 2022-06-22 2023-06-20 Composés pour le traitement de l'ataxie spinocérébelleuse de type 3 MA71255A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263354339P 2022-06-22 2022-06-22
PCT/US2023/068717 WO2023250316A1 (fr) 2022-06-22 2023-06-20 Composés pour le traitement de l'ataxie spinocérébelleuse de type 3
EP23827977.2A EP4543444A1 (fr) 2022-06-22 2023-06-20 Composés pour le traitement de l'ataxie spinocérébelleuse de type 3

Publications (1)

Publication Number Publication Date
MA71255A true MA71255A (fr) 2025-04-30

Family

ID=89380638

Family Applications (1)

Application Number Title Priority Date Filing Date
MA71255A MA71255A (fr) 2022-06-22 2023-06-20 Composés pour le traitement de l'ataxie spinocérébelleuse de type 3

Country Status (14)

Country Link
EP (1) EP4543444A1 (fr)
JP (1) JP2025521545A (fr)
KR (1) KR20250035623A (fr)
CN (1) CN119997954A (fr)
AU (1) AU2023289366A1 (fr)
CA (1) CA3259536A1 (fr)
CL (1) CL2024003939A1 (fr)
CO (1) CO2024017547A2 (fr)
CR (1) CR20240567A (fr)
IL (1) IL317705A (fr)
MA (1) MA71255A (fr)
MX (1) MX2024015863A (fr)
PE (1) PE20250836A1 (fr)
WO (1) WO2023250316A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021009667A (es) 2019-02-13 2021-12-10 Ptc Therapeutics Inc Compuestos de tioeno[3,2-b] piridin-7-amina para tratar la disautonomía familiar.
US12398140B2 (en) 2019-02-13 2025-08-26 Ptc Therapeutics, Inc. Substituted pyrrolo [2,3-d]pyrimidines for treating familial dysautonomia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8436043B2 (en) * 2008-03-05 2013-05-07 Takeda Pharmaceutical Company Limited Heterocyclic compound
MA39987A (fr) * 2014-04-30 2017-03-08 Incyte Corp Procédés de préparation d'un inhibiteur de jak1 et nouvelles formes associées
MX2021009667A (es) * 2019-02-13 2021-12-10 Ptc Therapeutics Inc Compuestos de tioeno[3,2-b] piridin-7-amina para tratar la disautonomía familiar.
EP3929185A4 (fr) * 2019-02-19 2023-02-15 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Composé cyclique condensé contenant de l'azote, son procédé de préparation et son utilisation

Also Published As

Publication number Publication date
KR20250035623A (ko) 2025-03-12
CL2024003939A1 (es) 2025-05-02
PE20250836A1 (es) 2025-03-21
CO2024017547A2 (es) 2025-03-27
IL317705A (en) 2025-02-01
CN119997954A (zh) 2025-05-13
EP4543444A1 (fr) 2025-04-30
CA3259536A1 (fr) 2023-12-28
AU2023289366A1 (en) 2025-01-23
CR20240567A (es) 2025-03-03
WO2023250316A1 (fr) 2023-12-28
JP2025521545A (ja) 2025-07-10
MX2024015863A (es) 2025-04-02

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