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Application filed by PfizerfiledCriticalPfizer
Priority claimed from PCT/IB2021/057281external-prioritypatent/WO2021250648A1/en
Publication of MA57215B1publicationCriticalpatent/MA57215B1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
L'invention concerne des composés de formule (i'') dans laquelle r, r1, r2, r3, p, q et q' sont tels que définis dans la description, des compositions pharmaceutiques comprenant les composés, des procédés de traitement d'une infection à coronavirus, telle que la covid-19 chez un patient, par administration de quantités thérapeutiquement efficaces des composés, et des procédés d'inhibition ou de prévention de la réplication de coronavirus tels que le sars-cov-2 avec les composés.The invention relates to compounds of formula (i'') wherein r, r1, r2, r3, p, q and q' are as defined in the description, pharmaceutical compositions comprising the compounds, methods of treating coronavirus infection, such as covid-19 in a patient, by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing replication of coronaviruses such as sars-cov-2 with the compounds.
MA57215A2020-09-032021-08-06
Compounds comprising a nitrile as antivirals for the treatment of coronavirus infection
MA57215B1
(en)
COMPOUND REPRESENTED BY FORMULA (I) OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OR PREVENTION OF A VIRAL INFECTION, METHOD OF INHIBITING VIRAL PROTEASE 3C OR VIRAL PROTEASE 3CL IN A MAMMAL, AND METHOD OF TREATMENT OF A DISORDER RESPIRATORY
BENZOCONDENSIC HETEROARYLAMIDE DERIVATIVES OF THIENOPYRIDINES USEFUL AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS FOR THEIR USE
Substituted 4-phenyltetrahydroisoquinolines, process for producing these compounds, use of these compounds as medicaments and medicament containing such compounds
COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OR PREVENTION OF VIRAL INFECTION AND RESPIRATORY DISORDERS AND METHOD OF INHIBITION OF VIRAL PROTEASE