MA55710A - Procédé de production de dérivés de 2-[2-(phényl)éthylamino]alcaneamide substitués - Google Patents

Procédé de production de dérivés de 2-[2-(phényl)éthylamino]alcaneamide substitués

Info

Publication number
MA55710A
MA55710A MA055710A MA55710A MA55710A MA 55710 A MA55710 A MA 55710A MA 055710 A MA055710 A MA 055710A MA 55710 A MA55710 A MA 55710A MA 55710 A MA55710 A MA 55710A
Authority
MA
Morocco
Prior art keywords
alcaneamide
ethylamino
phenyl
derivatives
substituted
Prior art date
Application number
MA055710A
Other languages
English (en)
Inventor
Christoph Imboden
Matthias Riepl
Wolfgang Skranc
Erwin Waldvogel
Michael Wolberg
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of MA55710A publication Critical patent/MA55710A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/08—Preparation of carboxylic acid nitriles by addition of hydrogen cyanide or salts thereof to unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MA055710A 2019-04-17 2020-04-08 Procédé de production de dérivés de 2-[2-(phényl)éthylamino]alcaneamide substitués MA55710A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19169714.3A EP3725768A1 (fr) 2019-04-17 2019-04-17 Procédé de production de dérivés de 2-[2-(phényl)éthylamino]alkanéamide

Publications (1)

Publication Number Publication Date
MA55710A true MA55710A (fr) 2022-02-23

Family

ID=66217869

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055710A MA55710A (fr) 2019-04-17 2020-04-08 Procédé de production de dérivés de 2-[2-(phényl)éthylamino]alcaneamide substitués

Country Status (16)

Country Link
US (1) US12134589B2 (fr)
EP (2) EP3725768A1 (fr)
JP (1) JP7651473B2 (fr)
KR (1) KR20210154206A (fr)
CN (1) CN113784944B (fr)
AR (1) AR118674A1 (fr)
AU (1) AU2020259726B2 (fr)
CA (1) CA3136845A1 (fr)
IL (1) IL287228B2 (fr)
MA (1) MA55710A (fr)
MX (1) MX2021012713A (fr)
MY (1) MY205088A (fr)
PH (1) PH12021552580A1 (fr)
SG (1) SG11202111378SA (fr)
TW (1) TWI844663B (fr)
WO (1) WO2020212227A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024223671A1 (fr) 2023-04-28 2024-10-31 Newron Pharmaceuticals S.P.A. Formes cristallines d'événamide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3832571A1 (de) 1988-09-24 1990-05-31 Boehringer Ingelheim Kg Verwendung von 2,7-diamino-1,2,3,4-tetrahydronaphthalinen als arzneimittel, neue 2,7-diamino-1,2,3,4-tetrahydronaphthaline sowie verfahren zu ihrer herstellung
US5593992A (en) 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
GB0127559D0 (en) 2001-11-16 2002-01-09 Syngenta Participations Ag Organic compounds
EA009589B1 (ru) * 2002-12-10 2008-02-28 Пфайзер Инк. Производные морфолина для применения в качестве агонистов допамина при лечении половой дисфункции
EP1685102A4 (fr) * 2003-11-12 2008-08-20 Lg Life Sciences Ltd Agonistes du recepteur de la melanocortine
NZ567540A (en) * 2005-12-22 2010-07-30 Newron Pharm Spa 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators
US8183413B2 (en) * 2006-01-20 2012-05-22 Kaneka Corporation Process for production of β-amino-α-hydroxy carboxamide derivative
ATE545626T1 (de) 2006-03-21 2012-03-15 Basf Se Verfahren zur herstellung eines amins
AU2008261325B2 (en) 2007-06-15 2012-12-06 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
EA019898B1 (ru) * 2007-12-11 2014-07-30 Ньюрон Фармасьютикалс С.П.А. Способ получения 2-[4-(3- или 2-фторбензилокси)бензиламино]пропанамидов с высокой степенью чистоты
JP5747625B2 (ja) 2011-04-12 2015-07-15 住友化学株式会社 マンデロニトリル化合物の製造方法
PL2723710T3 (pl) 2011-06-27 2017-02-28 Newron Pharmaceuticals S.P.A. Fluorowane pochodne aryloalkiloaminokarboksyamidowe
EP2824157B1 (fr) 2012-03-08 2020-02-12 Kyushu University Nouvel agent gélifiant dérivé de sucre
JP2016523941A (ja) * 2013-07-09 2016-08-12 バイエル ファーマ アクチエンゲゼルシャフト 改変されたｂｅｔタンパク質阻害性ジヒドロキノキサリノンおよびジヒドロピリドピラジノン
CN105801437A (zh) * 2016-03-31 2016-07-27 常州大学 一种(甲基氨基)(苯基)甲醇的合成方法
CN114249668B (zh) * 2020-09-25 2024-08-23 鲁南制药集团股份有限公司 一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Also Published As

Publication number Publication date
AU2020259726B2 (en) 2025-12-18
IL287228A (en) 2021-12-01
KR20210154206A (ko) 2021-12-20
JP7651473B2 (ja) 2025-03-26
MX2021012713A (es) 2021-11-12
CA3136845A1 (fr) 2020-10-22
TWI844663B (zh) 2024-06-11
PH12021552580A1 (en) 2022-08-01
TW202104164A (zh) 2021-02-01
IL287228B1 (en) 2024-10-01
US20220177417A1 (en) 2022-06-09
AU2020259726A1 (en) 2021-12-09
AR118674A1 (es) 2021-10-20
EP3956295A1 (fr) 2022-02-23
CN113784944B (zh) 2025-02-11
BR112021020599A2 (pt) 2021-12-07
MY205088A (en) 2024-10-01
JP2022529916A (ja) 2022-06-27
WO2020212227A1 (fr) 2020-10-22
IL287228B2 (en) 2025-02-01
CN113784944A (zh) 2021-12-10
EP3725768A1 (fr) 2020-10-21
US12134589B2 (en) 2024-11-05
SG11202111378SA (en) 2021-11-29

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