MA52902B1 - Composés d'acides aminés et leurs procédés d'utilisation - Google Patents
Composés d'acides aminés et leurs procédés d'utilisationInfo
- Publication number
- MA52902B1 MA52902B1 MA52902A MA52902A MA52902B1 MA 52902 B1 MA52902 B1 MA 52902B1 MA 52902 A MA52902 A MA 52902A MA 52902 A MA52902 A MA 52902A MA 52902 B1 MA52902 B1 MA 52902B1
- Authority
- MA
- Morocco
- Prior art keywords
- formula
- methods
- amino acid
- acid compounds
- compounds
- Prior art date
Links
- -1 AMINO ACID COMPOUNDS Chemical class 0.000 title 1
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000036971 interstitial lung disease 2 Diseases 0.000 abstract 2
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 108010021309 integrin beta6 Proteins 0.000 abstract 1
- 201000004071 non-specific interstitial pneumonia Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne des composés de formule (a) et de formule (i) ou un sel desdits composés, r1, r2, r10, r11, r12, r13, r14, r15, r16, q et p étant tels que définis dans la description. Les composés de formule (a), de formule (i) et les compositions pharmaceutiques les comprenant sont des inhibiteurs de l'intégrine a?ß6 qui sont utiles pour le traitement d'une fibrose, telle que la fibrose pulmonaire idiopathique (fpi) et la pneumonie interstitielle non spécifique (pins).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862639988P | 2018-03-07 | 2018-03-07 | |
| PCT/US2019/021243 WO2019173653A1 (fr) | 2018-03-07 | 2019-03-07 | Composés d'acides aminés et leurs procédés d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA52902A MA52902A (fr) | 2021-04-21 |
| MA52902B1 true MA52902B1 (fr) | 2024-02-29 |
Family
ID=90354477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA52902A MA52902B1 (fr) | 2018-03-07 | 2019-03-07 | Composés d'acides aminés et leurs procédés d'utilisation |
Country Status (1)
| Country | Link |
|---|---|
| MA (1) | MA52902B1 (fr) |
-
2019
- 2019-03-07 MA MA52902A patent/MA52902B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA52902A (fr) | 2021-04-21 |
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