MA47015A - OLIGOMERIC CONJUGATES OF EXON JUMPING FOR MUSCLE DYSTROPHY - Google Patents
OLIGOMERIC CONJUGATES OF EXON JUMPING FOR MUSCLE DYSTROPHYInfo
- Publication number
- MA47015A MA47015A MA047015A MA47015A MA47015A MA 47015 A MA47015 A MA 47015A MA 047015 A MA047015 A MA 047015A MA 47015 A MA47015 A MA 47015A MA 47015 A MA47015 A MA 47015A
- Authority
- MA
- Morocco
- Prior art keywords
- muscle dystrophy
- oligomeric conjugates
- exon
- jumping
- exon jumping
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3233—Morpholino-type ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3513—Protein; Peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/35—Special therapeutic applications based on a specific dosage / administration regimen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662436199P | 2016-12-19 | 2016-12-19 | |
PCT/US2017/066351 WO2018118627A1 (en) | 2016-12-19 | 2017-12-14 | Exon skipping oligomer conjugates for muscular dystrophy |
Publications (2)
Publication Number | Publication Date |
---|---|
MA47015A true MA47015A (en) | 2019-10-23 |
MA47015B1 MA47015B1 (en) | 2022-11-30 |
Family
ID=66326249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA47015A MA47015B1 (en) | 2016-12-19 | 2017-12-14 | Exon skipping oligomer conjugates for muscular dystrophy |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR110537A1 (en) |
MA (1) | MA47015B1 (en) |
-
2017
- 2017-12-14 MA MA47015A patent/MA47015B1/en unknown
- 2017-12-18 AR ARP170103552A patent/AR110537A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA47015B1 (en) | 2022-11-30 |
AR110537A1 (en) | 2019-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA55629A (en) | ANTIBODY COMPOSITIONS FOR THE TREATMENT OF TUMORS | |
MA44486A (en) | EARLY INTERVENTION METHODS TO PREVENT OR MITIGATE TOXICITY | |
MA46652A (en) | POLYTHERAPY FOR C3 INHIBITION | |
MA44054A (en) | BISPECIFIC ANTIBODY PLATFORM | |
MA46878A (en) | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | |
MA52801A (en) | OLIGOMERIC CONJUGATES TO EXON SKIP FOR MUSCLE DYSTROPHY | |
MA46048A (en) | BEGINNER KIT FOR TITRATION OF BASIC INSULIN | |
MA50533A (en) | IMIPRIDONES FOR GLIOMAS | |
FR3034840B3 (en) | FLEXIBLE LIGHTING ASSEMBLY FOR CURVED VENTS | |
FR3018964B1 (en) | INTERCONNECTION ELEMENT FOR CONNECTING STATOR COILS | |
FR3020758B1 (en) | COMPOSITION FOR IMPROVING BUCO-DENTAL HYGIENE | |
FR3023015B1 (en) | METHOD FOR FACILITATING THE APPROACH TO A PLATFORM | |
MA45845A (en) | COMBINATION TREATMENT FOR HEMATOLOGICAL CANCERS | |
MA46898A (en) | COMPOSITIONS FOR ORGAN CONSERVATION | |
FR3031502B1 (en) | POINT SET FOR AN INSTRUMENT | |
FR3028523B1 (en) | PROCESS FOR IMPROVING THE COKEFACTION RESISTANCE OF A LUBRICATING COMPOSITION | |
MA51822A (en) | ALKANOIC ACID EXTRACTION | |
FR3031206B1 (en) | INTERCONNECTION BOX FOR UTILITIES | |
FR3030253B1 (en) | COMPOSITION FOR IMPROVING THE CELLULAR ASPECT OF THE SKIN | |
FR3033489B3 (en) | GUIDE FOR THE POSITIONING OF ORTHODONTIC ATTACHES | |
MA47015A (en) | OLIGOMERIC CONJUGATES OF EXON JUMPING FOR MUSCLE DYSTROPHY | |
MA51582A (en) | OLIGOMERIC CONJUGATES OF EXON JUMPING FOR MUSCLE DYSTROPHY | |
MA51587A (en) | OLIGOMERIC CONJUGATES OF EXON JUMPING FOR MUSCLE DYSTROPHY | |
FR3046235B1 (en) | INTERCHANGEABLE SUPPORT FOR FASTENING A TURBOMACHINE | |
FR3040408B1 (en) | MODULAR WORK STRUCTURE FOR STAIR CAGE |