MA41873B2 - Anti-cd3 antibodies, bispecific antigen-binding molecules which bind to cd3 and cd20, and uses thereof - Google Patents
Anti-cd3 antibodies, bispecific antigen-binding molecules which bind to cd3 and cd20, and uses thereofInfo
- Publication number
- MA41873B2 MA41873B2 MA41873A MA41873A MA41873B2 MA 41873 B2 MA41873 B2 MA 41873B2 MA 41873 A MA41873 A MA 41873A MA 41873 A MA41873 A MA 41873A MA 41873 B2 MA41873 B2 MA 41873B2
- Authority
- MA
- Morocco
- Prior art keywords
- bind
- antibodies
- binding molecules
- bispecific antigen
- present
- Prior art date
Links
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne des anticorps qui se lient à cd3 et des procédés d'utilisation de ceux-ci. Selon certains modes de réalisation, les anticorps de l'invention se lient à cd3 humain à affinité élevée et induisent la prolifération de lymphocytes t humains. L'invention comprend des anticorps qui se lient à cd3 et induisent la mort à médiation par des lymphocytes t de cellules tumorales. Selon certains modes de réalisation, la présente invention concerne des molécules de liaison à un antigène bisThe present invention relates to antibodies that bind to cd3 and methods of using them. In some embodiments, the antibodies of the invention bind to high affinity human cd3 and induce proliferation of human t cells. The invention includes antibodies that bind to cd3 and induce t-cell mediated death of tumor cells. Embodiments of the present invention relate to bis antigen-binding molecules
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261704029P | 2012-09-21 | 2012-09-21 | |
PCT/US2013/060511 WO2014047231A1 (en) | 2012-09-21 | 2013-09-19 | Anti-cd3 antibodies, bispecific antigen-binding molecules that bind cd3 and cd20, and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MA41873A1 MA41873A1 (en) | 2018-07-31 |
MA41873B2 true MA41873B2 (en) | 2022-04-29 |
Family
ID=59745478
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37998A MA37998B2 (en) | 2012-09-21 | 2013-09-19 | Anti-cd3 antibodies, bispecific antigen-binding molecules that bind to cd3 and cd20, and their uses |
MA41873A MA41873B2 (en) | 2012-09-21 | 2013-09-19 | Anti-cd3 antibodies, bispecific antigen-binding molecules which bind to cd3 and cd20, and uses thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37998A MA37998B2 (en) | 2012-09-21 | 2013-09-19 | Anti-cd3 antibodies, bispecific antigen-binding molecules that bind to cd3 and cd20, and their uses |
Country Status (1)
Country | Link |
---|---|
MA (2) | MA37998B2 (en) |
-
2013
- 2013-09-19 MA MA37998A patent/MA37998B2/en unknown
- 2013-09-19 MA MA41873A patent/MA41873B2/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA41873A1 (en) | 2018-07-31 |
MA37998B2 (en) | 2020-07-29 |
MA37998A1 (en) | 2017-07-31 |
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