MA39204A1 - Heteroaryl derivatives inhibiting vps34 and / or p13 for the treatment of proliferative, inflammatory or cardiovascular disorders - Google Patents

Heteroaryl derivatives inhibiting vps34 and / or p13 for the treatment of proliferative, inflammatory or cardiovascular disorders

Info

Publication number
MA39204A1
MA39204A1 MA39204A MA39204A MA39204A1 MA 39204 A1 MA39204 A1 MA 39204A1 MA 39204 A MA39204 A MA 39204A MA 39204 A MA39204 A MA 39204A MA 39204 A1 MA39204 A1 MA 39204A1
Authority
MA
Morocco
Prior art keywords
inflammatory
proliferative
cardiovascular disorders
treatment
heteroaryl derivatives
Prior art date
Application number
MA39204A
Other languages
French (fr)
Other versions
MA39204B1 (en
Inventor
Indu T Bharathan
Chris Blackburn
Jeffrey P Ciavarri
Jouhara Chouitar
Courtney A Cullis
Natalie D'amore
Paul E Fleming
Kenneth M Gigstad
Krista E Gipson
Mario Girard
Yongbo Hu
Janice Lee
Gang Li
Mansoureh Rezaei
Michael D Sintchak
Francois Soucy
Stephen G Stroud
Tricia J Vos
Tzu-Tshin Wong
He Xu
Tianlin Xu
Yingchun Ye
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Priority claimed from PCT/US2015/011191 external-priority patent/WO2015108861A1/en
Publication of MA39204A1 publication Critical patent/MA39204A1/en
Publication of MA39204B1 publication Critical patent/MA39204B1/en

Links

Abstract

La présente invention concerne un composé de formule i : et des sels pharmaceutiquement acceptables dudit composé, x, r1, r2, r3, r4, r5, l1, l2, m, et n étant tels que décrits dans la description. Lesdits composés sont des inhibiteurs de vps34 et/ou de p13 et sont utilisés pour traiter des troubles prolifératifs, inflammatoires ou cardiovasculaires.The present invention relates to a compound of formula I: and pharmaceutically acceptable salts of said compound, x, r1, r2, r3, r4, r5, ll, 12, m, and n being as described in the description. The compounds are inhibitors of vps34 and / or p13 and are used to treat proliferative, inflammatory or cardiovascular disorders.

MA39204A 2014-01-14 2015-01-13 Heteroaryl derivatives inhibiting vps34 and / or p13 for the treatment of proliferative, inflammatory or cardiovascular disorders MA39204B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461927055P 2014-01-14 2014-01-14
PCT/US2015/011191 WO2015108861A1 (en) 2014-01-14 2015-01-13 Heteroaryls and uses thereof

Publications (2)

Publication Number Publication Date
MA39204A1 true MA39204A1 (en) 2017-11-30
MA39204B1 MA39204B1 (en) 2019-04-30

Family

ID=58698453

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39204A MA39204B1 (en) 2014-01-14 2015-01-13 Heteroaryl derivatives inhibiting vps34 and / or p13 for the treatment of proliferative, inflammatory or cardiovascular disorders

Country Status (2)

Country Link
AR (1) AR099093A1 (en)
MA (1) MA39204B1 (en)

Also Published As

Publication number Publication date
MA39204B1 (en) 2019-04-30
AR099093A1 (en) 2016-06-29

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MA39204B1 (en) Heteroaryl derivatives inhibiting vps34 and / or p13 for the treatment of proliferative, inflammatory or cardiovascular disorders