MA39120A1 - Substituted piperidinyl-tetrahydroquinolines antagonists adrenergic alpha-2c receptors. - Google Patents

Substituted piperidinyl-tetrahydroquinolines antagonists adrenergic alpha-2c receptors.

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Publication number
MA39120A1
MA39120A1 MA39120A MA39120A MA39120A1 MA 39120 A1 MA39120 A1 MA 39120A1 MA 39120 A MA39120 A MA 39120A MA 39120 A MA39120 A MA 39120A MA 39120 A1 MA39120 A1 MA 39120A1
Authority
MA
Morocco
Prior art keywords
diabetic
diseases
tetrahydroquinolines
prevention
treatment
Prior art date
Application number
MA39120A
Other languages
French (fr)
Inventor
Frank Wunder
Gorden Redlich
Andreas Knorr
Dieter Lang
Hanna Tinel
Raimund Kast
Philipp Buchgraber
Eva Maria Becker-Pelster
Anja Buchmüller
Karen Engel
Carsten Schmeck
Volker Geiss
Andreas Göller
Herbert Himmel
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Priority claimed from PCT/EP2014/077865 external-priority patent/WO2015091417A1/en
Publication of MA39120A1 publication Critical patent/MA39120A1/en

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Abstract

La présente invention concerne de nouvelles pipéridinyl-tétrahydroquinoléines substituées, des procédés pour leur production, leur utilisation dans le traitement et/ou la prévention de maladies et leur utilisation dans la production de médicaments destinés au traitement et/ou à la prévention de maladies, notamment le traitement et/ou la prévention de microangiopathies diabétiques, d'ulcères diabétiques aux extrémités, notamment pour favoriser la cicatrisation des ulcères du pied diabétique, l'insuffisance cardiaque diabétique, les maladie cardiaque microvasculaire coronariennes diabétiques, les maladies vasculaires cardiaques et périphériques, les maladies et les ischémies thromboemboliques, les troubles circulatoires périphériques, le syndrome de raynaud, le syndrome de crest, les déficiences de la microcirculation, la claudication intermittente, et les neuropathies périphériques et autonomes.The present invention relates to novel substituted piperidinyl tetrahydroquinolines, processes for their production, their use in the treatment and / or prevention of diseases and their use in the production of medicaments for the treatment and / or prevention of diseases, in particular the treatment and / or prevention of diabetic microangiopathies, diabetic ulcers at the extremities, in particular to promote the healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disease, cardiac and peripheral vascular diseases, thromboembolic diseases and ischemia, peripheral circulatory disorders, raynaud syndrome, crest syndrome, microcirculatory deficiencies, intermittent claudication, and peripheral and autonomic neuropathies.

MA39120A 2013-12-19 2014-12-16 Substituted piperidinyl-tetrahydroquinolines antagonists adrenergic alpha-2c receptors. MA39120A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13198388 2013-12-19
PCT/EP2014/077865 WO2015091417A1 (en) 2013-12-19 2014-12-16 Substituted piperidinyl-tetrahydroquinolines

Publications (1)

Publication Number Publication Date
MA39120A1 true MA39120A1 (en) 2017-11-30

Family

ID=49876402

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39120A MA39120A1 (en) 2013-12-19 2014-12-16 Substituted piperidinyl-tetrahydroquinolines antagonists adrenergic alpha-2c receptors.

Country Status (1)

Country Link
MA (1) MA39120A1 (en)

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