MA38479B1 - 3-pyrimidin-4-yl-oxazolidin-2-ones as mutant idh inhibitors - Google Patents

3-pyrimidin-4-yl-oxazolidin-2-ones as mutant idh inhibitors

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Publication number
MA38479B1
MA38479B1 MA38479A MA38479A MA38479B1 MA 38479 B1 MA38479 B1 MA 38479B1 MA 38479 A MA38479 A MA 38479A MA 38479 A MA38479 A MA 38479A MA 38479 B1 MA38479 B1 MA 38479B1
Authority
MA
Morocco
Prior art keywords
mutant idh
oxazolidin
pyrimidin
ones
idh inhibitors
Prior art date
Application number
MA38479A
Other languages
French (fr)
Other versions
MA38479A1 (en
Inventor
Young Shin Cho
Julian Roy Levell
Michael David Shultz
Abran Q Costales
Martin Sendzik
Cynthia Shafer
James Sutton
Qian Zhao
Thomas Raymond Caferro
Zhuoliang Chen
Gang Liu
James R Manning
Yaping Wang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority claimed from PCT/IB2014/059695 external-priority patent/WO2014141104A1/en
Publication of MA38479A1 publication Critical patent/MA38479A1/en
Publication of MA38479B1 publication Critical patent/MA38479B1/en

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Abstract

L'invention concerne également des compositions contenant un composé de formule (i) et l'utilisation de ces composés dans l'inhibition de protéines idh mutantes ayant une activité néomorphe. L'invention concerne en outre l'utilisation d'un composé de formule (i) dans le traitement de maladies ou de troubles associés à ces protéines idh mutante, comprenant, sans s'y limiter, des troubles de la prolifération cellulaire, comme le cancer.The invention also relates to compositions containing a compound of formula (i) and the use of these compounds in the inhibition of mutant idh proteins having neomorphous activity. The invention further relates to the use of a compound of formula (i) in the treatment of diseases or disorders associated with such mutant idh proteins, including, but not limited to, cell proliferation disorders, such as Cancer.

MA38479A 2013-03-14 2014-03-12 3-pyrimidin-4-yl-oxazolidin-2-ones as mutant idh inhibitors MA38479B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361783210P 2013-03-14 2013-03-14
PCT/IB2014/059695 WO2014141104A1 (en) 2013-03-14 2014-03-12 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh

Publications (2)

Publication Number Publication Date
MA38479A1 MA38479A1 (en) 2018-03-30
MA38479B1 true MA38479B1 (en) 2018-09-28

Family

ID=62203560

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38479A MA38479B1 (en) 2013-03-14 2014-03-12 3-pyrimidin-4-yl-oxazolidin-2-ones as mutant idh inhibitors

Country Status (1)

Country Link
MA (1) MA38479B1 (en)

Also Published As

Publication number Publication date
MA38479A1 (en) 2018-03-30

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