MA37464A1 - Anti-egfr antibodies and their uses - Google Patents
Anti-egfr antibodies and their usesInfo
- Publication number
- MA37464A1 MA37464A1 MA37464A MA37464A MA37464A1 MA 37464 A1 MA37464 A1 MA 37464A1 MA 37464 A MA37464 A MA 37464A MA 37464 A MA37464 A MA 37464A MA 37464 A1 MA37464 A1 MA 37464A1
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- egfr
- bind
- present
- egfr antibodies
- Prior art date
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention concerne des anticorps qui se lient à egfr et des procédés de son utilisation. Selon certains modes de réalisation de l'invention, les anticorps sont des anticorps complètement humains qui se lient à l'egfr humain avec une affinité élevée. Dans certains modes de réalisation, les anticorps de la présente invention sont aptes à inhiber la croissance de cellules tumorales exprimant des taux élevés d'egfr et/ou induisant une cytotoxicité à médiation cellulaire dépendante d'un anticorps (adcc) de telles cellules. Les anticorps de l'invention sont utiles pour le traitement de divers cancers, ainsi que pour d'autres troubles associés à egfr.The present invention relates to antibodies that bind to egfr and methods of its use. According to some embodiments of the invention, the antibodies are fully human antibodies that bind to human egfr with high affinity. In some embodiments, the antibodies of the present invention are capable of inhibiting the growth of tumor cells expressing high levels of egfr and / or inducing antibody-dependent cell-mediated cytotoxicity (adcc) of such cells. The antibodies of the invention are useful for the treatment of various cancers, as well as for other egfr-associated disorders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261663984P | 2012-06-25 | 2012-06-25 | |
PCT/US2013/047476 WO2014004427A2 (en) | 2012-06-25 | 2013-06-25 | Anti-egfr antibodies and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MA37464A1 true MA37464A1 (en) | 2016-03-31 |
MA37464B1 MA37464B1 (en) | 2018-03-30 |
Family
ID=56073199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37464A MA37464B1 (en) | 2012-06-25 | 2013-06-25 | Anti-egfr antibodies and their uses |
Country Status (1)
Country | Link |
---|---|
MA (1) | MA37464B1 (en) |
-
2013
- 2013-06-25 MA MA37464A patent/MA37464B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MA37464B1 (en) | 2018-03-30 |
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