MA32299B1 - Use of dronedarone to prepare a drug for the treatment of patients with arrhythmia and increased creatinine levels due to dronedarone administration - Google Patents

Use of dronedarone to prepare a drug for the treatment of patients with arrhythmia and increased creatinine levels due to dronedarone administration

Info

Publication number
MA32299B1
MA32299B1 MA33340A MA33340A MA32299B1 MA 32299 B1 MA32299 B1 MA 32299B1 MA 33340 A MA33340 A MA 33340A MA 33340 A MA33340 A MA 33340A MA 32299 B1 MA32299 B1 MA 32299B1
Authority
MA
Morocco
Prior art keywords
dronedarone
arrhythmia
treatment
patients
administration
Prior art date
Application number
MA33340A
Other languages
Arabic (ar)
French (fr)
Inventor
Sophie Claudel
Christophe Gaudin
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39680951&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32299(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MA32299B1 publication Critical patent/MA32299B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne l'utilisation de dronédarone, ou de l'un de ses sels pharmaceutiquement acceptables, dans la préparation d'un médicament destiné à traiter des patients souffrant d'arythmie. Lesdits patients présentent une augmentation du niveau de la créatinine due à l'administration de dronédarone, ledit niveau de créatinine augmentant suite à l'initiation d'un traitement à la dronédarone. Ladite augmentation du niveau de créatinine atteint un plateau et est utilisée en tant que nouvelle ligne de base. Cette augmentation est réversible après l'arrêt de la dronédarone.The present invention relates to the use of dronedarone, or a pharmaceutically acceptable salt thereof, in the preparation of a medicament for treating patients suffering from arrhythmia. Said patients have an increase in the level of creatinine due to the administration of dronedarone, said creatinine level increasing following the initiation of a treatment with dronedarone. Said increase in creatinine level reaches a plateau and is used as a new baseline. This increase is reversible after discontinuation of dronedarone.

MA33340A 2008-04-28 2010-11-11 Use of dronedarone to prepare a drug for the treatment of patients with arrhythmia and increased creatinine levels due to dronedarone administration MA32299B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4873208P 2008-04-28 2008-04-28
EP08290407A EP2116239A1 (en) 2008-04-29 2008-04-29 Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment
PCT/IB2009/005930 WO2009133470A2 (en) 2008-04-28 2009-04-28 Use of dronedarone for preparing a medicament for the treatment of patients with arrhythmia and having an increase of creatinine level due to dronedarone administration

Publications (1)

Publication Number Publication Date
MA32299B1 true MA32299B1 (en) 2011-05-02

Family

ID=39680951

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33340A MA32299B1 (en) 2008-04-28 2010-11-11 Use of dronedarone to prepare a drug for the treatment of patients with arrhythmia and increased creatinine levels due to dronedarone administration

Country Status (27)

Country Link
US (1) US20100016423A1 (en)
EP (2) EP2116239A1 (en)
JP (1) JP2011518872A (en)
KR (1) KR20100135853A (en)
CN (1) CN102076337A (en)
AR (1) AR072954A1 (en)
AU (1) AU2009241286A1 (en)
BR (1) BRPI0912706A2 (en)
CA (1) CA2722815A1 (en)
CL (1) CL2009001018A1 (en)
CO (1) CO6311076A2 (en)
DO (1) DOP2010000327A (en)
EA (1) EA201071138A1 (en)
EC (1) ECSP10010567A (en)
IL (1) IL208900A0 (en)
MA (1) MA32299B1 (en)
MX (1) MX2010011873A (en)
NI (1) NI201000181A (en)
NZ (1) NZ588886A (en)
PA (1) PA8824601A1 (en)
PE (1) PE20091885A1 (en)
SG (1) SG188180A1 (en)
TW (1) TW200948355A (en)
UA (1) UA100883C2 (en)
UY (1) UY31790A (en)
WO (1) WO2009133470A2 (en)
ZA (1) ZA201007727B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280701A2 (en) 2008-04-17 2011-02-09 Sanofi-Aventis Use of dronedarone for the preparation of a medicament for use in the prevention of cardiovascular hospitalization or of mortality
FR2930149B1 (en) * 2008-04-17 2011-02-18 Sanofi Aventis ASSOCIATION OF DRONEDARONE WITH AT LEAST ONE DIURETIC, ITS THERAPEUTIC APPLICATION
FR2959132A1 (en) * 2010-04-22 2011-10-28 Sanofi Aventis METHODS FOR RISK EVALUATION AND REDUCTION
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
WO2012023024A2 (en) * 2010-08-17 2012-02-23 Lupin Limited Controlled release formulations of dronedarone
RU2456019C1 (en) * 2011-03-29 2012-07-20 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию" Method for prediction of developing life-threatening ventricular arrhythmias in patients with no structural cardiac changes

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FR2735365B1 (en) * 1995-06-14 1997-09-05 Sanofi Sa USE OF AN ANGIOTENSIN II ANTAGONIST AND A BENZOFURANE DERIVATIVE FOR THE PREPARATION OF A MEDICAMENT USEFUL IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS
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FR2817865B1 (en) * 2000-12-11 2005-02-18 Sanofi Synthelabo AMINOALKOXYBENZOYLE DERIVATIVE IN SALT FORM, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS SYNTHESIS INTERMEDIATE
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EP2280701A2 (en) * 2008-04-17 2011-02-09 Sanofi-Aventis Use of dronedarone for the preparation of a medicament for use in the prevention of cardiovascular hospitalization or of mortality
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EP2153830A1 (en) * 2008-08-07 2010-02-17 Sanofi-Aventis Use of dronedarone for the preparation of a medicament intended for the prevention of stroke or transient ischemic attack

Also Published As

Publication number Publication date
JP2011518872A (en) 2011-06-30
NI201000181A (en) 2012-03-15
KR20100135853A (en) 2010-12-27
PE20091885A1 (en) 2009-12-31
UY31790A (en) 2009-12-14
ECSP10010567A (en) 2010-11-30
DOP2010000327A (en) 2011-01-31
PA8824601A1 (en) 2009-12-16
EP2116239A1 (en) 2009-11-11
IL208900A0 (en) 2011-01-31
CL2009001018A1 (en) 2011-01-07
EA201071138A1 (en) 2011-06-30
UA100883C2 (en) 2013-02-11
CA2722815A1 (en) 2009-11-05
WO2009133470A2 (en) 2009-11-05
US20100016423A1 (en) 2010-01-21
WO2009133470A3 (en) 2009-12-23
NZ588886A (en) 2013-01-25
AU2009241286A1 (en) 2009-11-05
ZA201007727B (en) 2013-01-30
CN102076337A (en) 2011-05-25
AR072954A1 (en) 2010-10-06
BRPI0912706A2 (en) 2017-06-13
CO6311076A2 (en) 2011-08-22
EP2291183A2 (en) 2011-03-09
MX2010011873A (en) 2011-04-05
SG188180A1 (en) 2013-03-28
TW200948355A (en) 2009-12-01

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