MA31681B1 - Semi - particles of influenza virus (VLP) a blood ligament (HA) produced in a plant - Google Patents

Semi - particles of influenza virus (VLP) a blood ligament (HA) produced in a plant

Info

Publication number
MA31681B1
MA31681B1 MA32604A MA32604A MA31681B1 MA 31681 B1 MA31681 B1 MA 31681B1 MA 32604 A MA32604 A MA 32604A MA 32604 A MA32604 A MA 32604A MA 31681 B1 MA31681 B1 MA 31681B1
Authority
MA
Morocco
Prior art keywords
vlp
plant
influenza
particles
influenza virus
Prior art date
Application number
MA32604A
Other languages
Arabic (ar)
French (fr)
Inventor
Aoust Marc-André D
Manon Couture
Frédéric Ors
Sonia Trepanier
Pierre-Olivier Lavoie
Michèle Dargis
Louis-Philippe Vezina
Nathalie Landry
Original Assignee
Medicago Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002615372A external-priority patent/CA2615372A1/en
Application filed by Medicago Inc filed Critical Medicago Inc
Publication of MA31681B1 publication Critical patent/MA31681B1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention porte sur un procédé de synthèse de pseudo-particules du virus de la grippe (vlp) dans une plante ou dans une partie de la plante. Le procédé met en jeu l'expression de la ha de la grippe dans des plantes et la purification par chromatographie d'exclusion stérique. L'invention se rapporte également à une vlp comprenant une protéine ha grippale et des lipides végétaux. L'invention porte enfin sur un acide nucléique codant pour une ha grippale ainsi que sur des vecteurs. Les vlp peuvent être utilisés pour formuler des vaccins contre la grippe ou enrichir des vaccins existants.The invention relates to a method for the synthesis of influenza virus-like particles (vlp) in a plant or in a part of the plant. The method involves expression of influenza ha in plants and purification by size exclusion chromatography. The invention also relates to a vlp comprising an influenza ha protein and plant lipids. The invention finally relates to a nucleic acid encoding an influenza ha as well as to vectors. vlp's can be used to formulate influenza vaccines or enrich existing vaccines.

MA32604A 2007-07-13 2010-02-08 Semi - particles of influenza virus (VLP) a blood ligament (HA) produced in a plant MA31681B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US95941407P 2007-07-13 2007-07-13
US99060307P 2007-11-27 2007-11-27
US1327207P 2007-12-12 2007-12-12
CA002615372A CA2615372A1 (en) 2007-07-13 2008-01-21 Influenza virus-like particles (vlps) comprising hemagglutinin
US2277508P 2008-01-22 2008-01-22
PCT/CA2008/001281 WO2009009876A1 (en) 2007-07-13 2008-07-11 Influenza virus-like particles (vlps) comprising hemagglutinin produced within a plant

Publications (1)

Publication Number Publication Date
MA31681B1 true MA31681B1 (en) 2010-09-01

Family

ID=44083973

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32604A MA31681B1 (en) 2007-07-13 2010-02-08 Semi - particles of influenza virus (VLP) a blood ligament (HA) produced in a plant

Country Status (5)

Country Link
HK (1) HK1142627A1 (en)
IL (2) IL203018A (en)
IS (1) IS2920B (en)
MA (1) MA31681B1 (en)
ZA (1) ZA201000972B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX370690B (en) 2008-07-18 2019-12-19 Medicago Inc New influenza virus immunizing epitope.

Also Published As

Publication number Publication date
IL230708A (en) 2015-02-26
IS8874A (en) 2010-01-27
BRPI0813724A2 (en) 2020-08-04
IS2920B (en) 2015-02-15
HK1142627A1 (en) 2010-12-10
ZA201000972B (en) 2010-10-27
IL203018A (en) 2015-01-29
IL203018A0 (en) 2011-08-01
IL230708A0 (en) 2014-03-31

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