MA31356B1 - USE OF HDAC INHIBITORS FOR THE TREATMENT OF GASTROINTESTINAL CANCERS - Google Patents
USE OF HDAC INHIBITORS FOR THE TREATMENT OF GASTROINTESTINAL CANCERSInfo
- Publication number
- MA31356B1 MA31356B1 MA32315A MA32315A MA31356B1 MA 31356 B1 MA31356 B1 MA 31356B1 MA 32315 A MA32315 A MA 32315A MA 32315 A MA32315 A MA 32315A MA 31356 B1 MA31356 B1 MA 31356B1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- gastrointestinal cancers
- hdac inhibitors
- relates
- hdac
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
Abstract
La présente invention concerne l'utilisation d'un inhibiteur de la hdac pour préparer un médicament destiné au traitement des cancers gastro-intestinaux. L'invention concerne également un procédé de traitement d'un animal à sang chaud, en particulier un être humain, ayant un cancer gastro-intestinal, ledit procédé comprenant l'administration audit animal d'une quantité thérapeutiquement efficace d'un inhibiteur de la hdac, en particulier un composé de formule (i) tel que défini ici. L'invention concerne en outre une composition pharmaceutique et un emballage commercial.The present invention relates to the use of a hdac inhibitor for preparing a medicament for the treatment of gastrointestinal cancers. The invention also relates to a method of treating a warm blooded animal, in particular a human, having gastrointestinal cancer, said method comprising administering to said animal a therapeutically effective amount of a cancer inhibitor. hdac, in particular a compound of formula (i) as defined herein. The invention further relates to a pharmaceutical composition and a commercial package.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91599607P | 2007-05-04 | 2007-05-04 | |
| PCT/US2008/062341 WO2008137630A1 (en) | 2007-05-04 | 2008-05-02 | Use of hdac inhibitors for the treatment of gastrointestinal cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA31356B1 true MA31356B1 (en) | 2010-05-03 |
Family
ID=39683987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA32315A MA31356B1 (en) | 2007-05-04 | 2009-10-30 | USE OF HDAC INHIBITORS FOR THE TREATMENT OF GASTROINTESTINAL CANCERS |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP2142190A1 (en) |
| JP (1) | JP2010526149A (en) |
| KR (1) | KR20100016171A (en) |
| CN (1) | CN101674825A (en) |
| AU (1) | AU2008247603A1 (en) |
| BR (1) | BRPI0811112A2 (en) |
| CA (1) | CA2683554A1 (en) |
| CL (1) | CL2008001269A1 (en) |
| IL (1) | IL201318A0 (en) |
| MA (1) | MA31356B1 (en) |
| MX (1) | MX2009011692A (en) |
| RU (1) | RU2009144842A (en) |
| TN (1) | TN2009000427A1 (en) |
| TW (1) | TW200908964A (en) |
| WO (1) | WO2008137630A1 (en) |
| ZA (1) | ZA200906739B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020354A1 (en) * | 2000-09-01 | 2002-06-12 | Novartis Ag | HYDROXAMATE COMPOUNDS AS HISTONE-DESACETILASE (HDA) INHIBITORS |
| US20070167499A1 (en) * | 2003-10-27 | 2007-07-19 | A*Bio Pte Ltd. | Biaryl linked hydroxamates: preparation and pharmaceutical applications |
| MXPA06004735A (en) * | 2003-10-27 | 2006-12-14 | S Bio Pte Ltd | Acylurea connected and sulfonylurea connected hydroxamates. |
| WO2006075165A1 (en) * | 2005-01-13 | 2006-07-20 | Btg International Limited | Combination of oncolytic viruses with angiogenesis inhibitors |
-
2008
- 2008-05-02 MX MX2009011692A patent/MX2009011692A/en not_active Application Discontinuation
- 2008-05-02 JP JP2010507547A patent/JP2010526149A/en not_active Withdrawn
- 2008-05-02 KR KR1020097022965A patent/KR20100016171A/en not_active Application Discontinuation
- 2008-05-02 EP EP08747442A patent/EP2142190A1/en not_active Withdrawn
- 2008-05-02 TW TW097116351A patent/TW200908964A/en unknown
- 2008-05-02 AU AU2008247603A patent/AU2008247603A1/en not_active Abandoned
- 2008-05-02 BR BRPI0811112-0A2A patent/BRPI0811112A2/en not_active IP Right Cessation
- 2008-05-02 CN CN200880014107A patent/CN101674825A/en active Pending
- 2008-05-02 CA CA002683554A patent/CA2683554A1/en not_active Abandoned
- 2008-05-02 WO PCT/US2008/062341 patent/WO2008137630A1/en active Application Filing
- 2008-05-02 CL CL2008001269A patent/CL2008001269A1/en unknown
- 2008-05-02 RU RU2009144842/15A patent/RU2009144842A/en not_active Application Discontinuation
-
2009
- 2009-09-28 ZA ZA200906739A patent/ZA200906739B/en unknown
- 2009-10-01 IL IL201318A patent/IL201318A0/en unknown
- 2009-10-16 TN TNP2009000427A patent/TN2009000427A1/en unknown
- 2009-10-30 MA MA32315A patent/MA31356B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008137630A1 (en) | 2008-11-13 |
| AU2008247603A1 (en) | 2008-11-13 |
| RU2009144842A (en) | 2011-06-10 |
| JP2010526149A (en) | 2010-07-29 |
| IL201318A0 (en) | 2010-05-31 |
| EP2142190A1 (en) | 2010-01-13 |
| BRPI0811112A2 (en) | 2014-12-23 |
| MX2009011692A (en) | 2009-11-10 |
| TW200908964A (en) | 2009-03-01 |
| ZA200906739B (en) | 2010-06-30 |
| KR20100016171A (en) | 2010-02-12 |
| TN2009000427A1 (en) | 2011-03-31 |
| CN101674825A (en) | 2010-03-17 |
| CA2683554A1 (en) | 2008-11-13 |
| CL2008001269A1 (en) | 2008-12-19 |
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