LV14476A - Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles - Google Patents

Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles

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Publication number
LV14476A
LV14476A LVP-11-167A LV110167A LV14476A LV 14476 A LV14476 A LV 14476A LV 110167 A LV110167 A LV 110167A LV 14476 A LV14476 A LV 14476A
Authority
LV
Latvia
Prior art keywords
tetrahydroindazoles
acylamino
sythesis
biologically active
dihydroindazoles
Prior art date
Application number
LVP-11-167A
Other languages
Latvian (lv)
Other versions
LV14476B (en
Inventor
Māris TURKS
Inta Strakova
Kirils GOROVOJS
Yury A. Piven
Tatsiana S. Khlebnikava
Fiodor A. Lakhvich
Marina B. GOLUBEVA
Inha A. Kantrouskaya
Original Assignee
Rīgas Tehniskā Universitāte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rīgas Tehniskā Universitāte filed Critical Rīgas Tehniskā Universitāte
Priority to LVP-11-167A priority Critical patent/LV14476B/en
Publication of LV14476A publication Critical patent/LV14476A/en
Publication of LV14476B publication Critical patent/LV14476B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention provides a novel method of synthesis of 4-acylamino-4,5,6,7-tetrahydroindazoles with general formula (I). The method consists of Ritter reaction between 4-hydroxy-4,5,6,7-tetrahydroindazoles or 6,7-dihydroindazoles and various nitriles in acidic medium which generates the corresponding tetrahydroindazolyl cation. Compounds (I) possess analgesic activity.
LVP-11-167A 2011-12-07 2011-12-07 Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles LV14476B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
LVP-11-167A LV14476B (en) 2011-12-07 2011-12-07 Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-11-167A LV14476B (en) 2011-12-07 2011-12-07 Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles

Publications (2)

Publication Number Publication Date
LV14476A true LV14476A (en) 2012-02-20
LV14476B LV14476B (en) 2012-05-20

Family

ID=50152812

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-11-167A LV14476B (en) 2011-12-07 2011-12-07 Sythesis of biologically active 4-acylamino-4,5,6,7-tetrahydroindazoles

Country Status (1)

Country Link
LV (1) LV14476B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889564B2 (en) 2015-11-02 2021-01-12 Genase Therapeutics B.V. Tetrahydroindazoles and medical uses thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10889564B2 (en) 2015-11-02 2021-01-12 Genase Therapeutics B.V. Tetrahydroindazoles and medical uses thereof
EP3974424A1 (en) 2015-11-02 2022-03-30 Genase Therapeutics B.V. Tetrahydroindazoles and medical uses thereof
US11795157B2 (en) 2015-11-02 2023-10-24 Genase Therapeutics B.V. Tetrahydroindazoles and medical uses thereof

Also Published As

Publication number Publication date
LV14476B (en) 2012-05-20

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