LU92588B1 - Means and methods for site-specific functionalization of polypeptides - Google Patents

Means and methods for site-specific functionalization of polypeptides

Info

Publication number
LU92588B1
LU92588B1 LU92588A LU92588A LU92588B1 LU 92588 B1 LU92588 B1 LU 92588B1 LU 92588 A LU92588 A LU 92588A LU 92588 A LU92588 A LU 92588A LU 92588 B1 LU92588 B1 LU 92588B1
Authority
LU
Luxembourg
Prior art keywords
polypeptides
site
methods
specific functionalization
functionalization
Prior art date
Application number
LU92588A
Inventor
Heinrich Leonhardt
Jonas Helma
Dominik Schumacher
Christian Hackenberger
Original Assignee
Univ Muenchen L Maximilians
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to LU92588A priority Critical patent/LU92588B1/en
Application filed by Univ Muenchen L Maximilians filed Critical Univ Muenchen L Maximilians
Priority to CA2964837A priority patent/CA2964837C/en
Priority to US15/521,675 priority patent/US10208084B2/en
Priority to EP15801687.3A priority patent/EP3212659B1/en
Priority to ES15801687T priority patent/ES2800164T3/en
Priority to PL15801687T priority patent/PL3212659T3/en
Priority to HUE15801687A priority patent/HUE049632T2/en
Priority to DK15801687.3T priority patent/DK3212659T3/en
Priority to AU2015340591A priority patent/AU2015340591B2/en
Priority to PCT/EP2015/075130 priority patent/WO2016066749A1/en
Priority to EP20165818.4A priority patent/EP3733687A1/en
Application granted granted Critical
Publication of LU92588B1 publication Critical patent/LU92588B1/en
Priority to US16/225,522 priority patent/US10745437B2/en
Priority to US16/993,877 priority patent/US11401298B2/en
Priority to US17/853,591 priority patent/US11958880B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y603/00—Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/02—Acid—amino-acid ligases (peptide synthases)(6.3.2)
    • C12Y603/02025—Tubulin-tyrosine ligase (6.3.2.25)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
LU92588A 2014-10-29 2014-10-29 Means and methods for site-specific functionalization of polypeptides LU92588B1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
LU92588A LU92588B1 (en) 2014-10-29 2014-10-29 Means and methods for site-specific functionalization of polypeptides
AU2015340591A AU2015340591B2 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
EP15801687.3A EP3212659B1 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
ES15801687T ES2800164T3 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
PL15801687T PL3212659T3 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
HUE15801687A HUE049632T2 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
CA2964837A CA2964837C (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
US15/521,675 US10208084B2 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
PCT/EP2015/075130 WO2016066749A1 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
EP20165818.4A EP3733687A1 (en) 2014-10-29 2015-10-29 Means and methods for site-specific functionalization of polypeptides
DK15801687.3T DK3212659T3 (en) 2014-10-29 2015-10-29 METHODS AND PROCEDURES FOR LOCAL SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
US16/225,522 US10745437B2 (en) 2014-10-29 2018-12-19 Means and methods for site-specific functionalization of polypeptides
US16/993,877 US11401298B2 (en) 2014-10-29 2020-08-14 Means and methods for site-specific functionalization of polypeptides
US17/853,591 US11958880B2 (en) 2014-10-29 2022-06-29 Means and methods for site-specific functionalization of polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU92588A LU92588B1 (en) 2014-10-29 2014-10-29 Means and methods for site-specific functionalization of polypeptides

Publications (1)

Publication Number Publication Date
LU92588B1 true LU92588B1 (en) 2016-05-02

Family

ID=51945981

Family Applications (1)

Application Number Title Priority Date Filing Date
LU92588A LU92588B1 (en) 2014-10-29 2014-10-29 Means and methods for site-specific functionalization of polypeptides

Country Status (1)

Country Link
LU (1) LU92588B1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015041729A2 (en) * 2013-06-03 2015-03-26 The Research Foundation Of State University Of New York SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015041729A2 (en) * 2013-06-03 2015-03-26 The Research Foundation Of State University Of New York SITE-SPECIFIC ORTHOGONAL LABELING OF THE CARBOXY TERMINUS OF α-TUBULIN IN LIVE CELLS

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A E PROTA ET AL.: "Structural basis of tubulin tyrosination by tuibulin tyrosine ligase", THE JOURNAL OF CELL BIOLOGY : JCB, vol. 200, no. 3, 28 January 2013 (2013-01-28), The Rockefeller University Press, pages 259 - 270, XP002741134, ISSN: 0021-9525 *
M RÜDIGER ET AL.: "The carboxy-terminal peptide of detyrosinated alpha tubulin provides a minimal system to study the substrate specificity of tubulin-tyrosine kinase", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 220, no. 2, 1994, Wiley-Blackwell Publishing Ltd., pages 309 - 320, XP002741133, ISSN: 0014-2956 *

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