LTIP266A - Process for the preparation of a standardized human von willebrand factor concentrate for therapeutical use - Google Patents

Process for the preparation of a standardized human von willebrand factor concentrate for therapeutical use

Info

Publication number
LTIP266A
LTIP266A LTIP266A LTIP266A LTIP266A LT IP266 A LTIP266 A LT IP266A LT IP266 A LTIP266 A LT IP266A LT IP266 A LTIP266 A LT IP266A LT IP266 A LTIP266 A LT IP266A
Authority
LT
Lithuania
Prior art keywords
preparation
von willebrand
willebrand factor
standardized human
human von
Prior art date
Application number
LTIP266A
Inventor
Miryana Burnouf-Radosevich
Thierry Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of LTIP266A publication Critical patent/LTIP266A/en
Publication of LT3175B publication Critical patent/LT3175B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP266A 1991-03-08 1992-12-30 Process for the preparation of a standardized human von willebrand factor concentrate for therapeutical use LT3175B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102804A FR2673632A1 (en) 1991-03-08 1991-03-08 PROCESS FOR THE PREPARATION OF HUMAN VON WILLEBRAND FACTOR CONCENTRATE OF HIGH PURITY, SUITABLE FOR THERAPEUTIC USE

Publications (2)

Publication Number Publication Date
LTIP266A true LTIP266A (en) 1994-07-15
LT3175B LT3175B (en) 1995-02-27

Family

ID=9410505

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP266A LT3175B (en) 1991-03-08 1992-12-30 Process for the preparation of a standardized human von willebrand factor concentrate for therapeutical use

Country Status (29)

Country Link
US (1) US5408039A (en)
EP (1) EP0503991B1 (en)
JP (1) JP3435668B2 (en)
AT (1) AT407115B (en)
AU (1) AU645172B2 (en)
BE (1) BE1004178A3 (en)
BR (1) BR9200770A (en)
CA (1) CA2062340C (en)
CZ (1) CZ283633B6 (en)
DE (2) DE122009000034I2 (en)
DK (1) DK0503991T3 (en)
EE (1) EE03057B1 (en)
EG (1) EG20300A (en)
ES (1) ES2121830T3 (en)
FI (1) FI106721B (en)
FR (1) FR2673632A1 (en)
HU (1) HU215098B (en)
IL (1) IL101043A (en)
IT (1) IT1256692B (en)
LT (1) LT3175B (en)
NL (1) NL300394I1 (en)
NO (1) NO301278B1 (en)
NZ (1) NZ241701A (en)
PL (1) PL168353B1 (en)
RU (1) RU2088590C1 (en)
SA (1) SA92120446B1 (en)
SK (1) SK279533B6 (en)
UA (1) UA27732C2 (en)
ZA (1) ZA921430B (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4435485C1 (en) * 1994-10-04 1996-03-21 Immuno Ag Process for obtaining high-purity von Willebrand factor
DE4435392B4 (en) * 1994-10-04 2008-02-07 Immuno Ag Method for separating vWF into high molecular weight vWF and low molecular weight vWF
DE4437544A1 (en) * 1994-10-20 1996-04-25 Behringwerke Ag Use of vWF-containing concentrates as combination therapy for therapy with antithrombotics and fibrinolytics
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
DE19616540A1 (en) * 1995-11-10 1997-05-15 Immuno Ag Use of von Willebrand factor and pharmaceutical preparation
US6005077A (en) * 1995-11-10 1999-12-21 Immuno Aktiengesellschaft Use of von willebrand factor and pharmaceutical formulation
AT403764B (en) 1996-03-15 1998-05-25 Immuno Ag STABLE FACTOR VIII / VWF COMPLEX
US6068838A (en) * 1996-04-29 2000-05-30 Baxter Aktiengesellschaft Purified multimerase
AT404358B (en) * 1997-02-04 1998-11-25 Immuno Ag METHOD FOR CHROMATOGRAPHIC CLEANING OR FRACTIONATION OF VON WILLEBRAND FACTOR FROM A VWF-CONTAINING MATERIAL
AT405403B (en) 1997-02-27 1999-08-25 Immuno Ag CLEANING OF WILLEBRAND FACTOR BY CATION EXCHANGER CHROMATOGRAPHY
AT405485B (en) * 1997-05-28 1999-08-25 Immuno Ag A PHARMACEUTICAL PREPARATION CONTAINING THE VWF PROPEPTIDE
DK2193809T3 (en) 1999-02-22 2015-05-26 Univ Connecticut The albumin-free Factor VIII formulation
EP1148063A1 (en) * 2000-04-18 2001-10-24 Octapharma AG Composition containing hemostatic activ vWF and process for its preparation
EP1593388A1 (en) * 2004-05-05 2005-11-09 ZLB Behring GmbH Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers
FR2874216B1 (en) 2004-08-16 2006-11-03 Lab Francais Du Fractionnement PROCESS FOR THE PREPARATION OF A VON WILLEBRAND FACTOR CONCENTRATE (FVW) BY CHROMATOGRAPHIC AND CONCENTRATED FVW SO LIKELY TO BE OBTAINED
DE102004044419B4 (en) 2004-09-14 2010-04-15 Biotest Ag Process for the purification of a von Willebrand factor by means of hydroxylapatite continuous chromatography
DE102004044429B4 (en) * 2004-09-14 2009-04-30 Biotest Ag Process for the preparation of a composition containing von Willebrand factor
ITLU20070007A1 (en) * 2007-05-07 2008-11-08 Kedrion Spa CHROMATOGRAPHIC PROCESS FOR OBTAINING A FVIII / VWF COMPLEX WITH DIFFERENT RELATIONSHIPS BETWEEN THE TWO PROTEINS TO BE USED IN THE HEMOPHILIA A THERAPY AND IN VON WILLEBRAND'S DISEASE.
EP2486936A1 (en) 2007-06-13 2012-08-15 CSL Behring GmbH A composition comprising VWF and FVIII preparations for use in treating of bleeding disorders
FR2920429B1 (en) * 2007-08-30 2012-10-05 Lfb Biotechnologies PROCESS FOR PURIFYING FACTOR VIII AND VON WILLEBRAND FACTOR
EP2073015A1 (en) 2007-12-21 2009-06-24 CSL Behring GmbH Diagnostic in vitro method for assessing Von Willebrand Disease and bleeding risk associated with Von Willebrand Disease and acquired or congenital disorders of platelet function
US20100273206A1 (en) * 2007-12-21 2010-10-28 Manfred Rauh Diagnostic in vitro method for assessing von willebrand disease and increased bleeding risk associated with von willebrand disease and acquired or congenital disorders of platelet function
CN103739712B (en) 2008-06-24 2016-10-05 德国杰特贝林生物制品有限公司 There is the Factor IX of the Half-life in vivo of prolongation, vWF or their complex
MX339060B (en) 2008-11-07 2016-05-09 Baxter Int Factor viii formulations.
IT1396528B1 (en) 2009-01-19 2012-12-14 Kedrion Spa NEW HIGHLY SELECTIVE PURIFICATION PROCESS OF TWO PLASMATIC PROTEINS: VON WILLEBRAND FACTOR (VWF) AND FIBRONECTIN (FN).
US20120148557A1 (en) 2009-08-20 2012-06-14 Ulrich Kronthaler Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
AU2012318279B2 (en) 2011-10-18 2015-06-04 Csl Behring Gmbh Use of sulfated glycosaminoglycans for improving the bioavailability of Factor VIII
JP6029674B2 (en) 2011-10-18 2016-11-24 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー Use of a combination of sulfated glycosaminoglycan and hyaluronidase to improve the bioavailability of factor VIII
EP2814502B1 (en) 2012-02-15 2017-09-13 CSL Behring GmbH Von willebrand factor variants having improved factor viii binding affinity
DK2796145T3 (en) 2013-04-22 2018-01-29 Csl Ltd A covalent complex of von Willebrand factor and factor VIII linked by a disulfide bridge
CN105705516B (en) 2013-11-08 2019-11-01 杰特有限公司 The von Willebrand factor or the method for its complex compound is concentrated
ES2844232T3 (en) 2014-07-02 2021-07-21 CSL Behring Lengnau AG Modified von Willebrand factor
US10626164B2 (en) 2014-07-25 2020-04-21 Csl Limited Purification of VWF
FR3034669B1 (en) 2015-04-07 2020-02-14 Laboratoire Francais Du Fractionnement Et Des Biotechnologies NEW USE OF THE VON WILLEBRAND FACTOR
WO2017066683A1 (en) * 2015-10-15 2017-04-20 Plasma Technologies, Llc Methods for extracting proteins from blood plasma
EP3400238B1 (en) 2016-01-07 2021-05-19 CSL Behring Lengnau AG Mutated von willebrand factor
SG10201912498YA (en) 2016-01-07 2020-02-27 CSL Behring Lengnau AG Mutated truncated von willebrand factor
CN105622746A (en) * 2016-02-04 2016-06-01 江西博雅生物制药股份有限公司 Preparation process for extracting human von Willebrand factor from waste of cryoprecipitate extraction blood coagulation factor VIII
CN105541997A (en) * 2016-02-04 2016-05-04 江西博雅生物制药股份有限公司 Preparation process of high-purity and high-activity von Willebrand factors
CN105622747A (en) * 2016-02-04 2016-06-01 江西博雅生物制药股份有限公司 vWF (von Willebrand factor) activity protection fluid
EP3488858A1 (en) 2017-11-27 2019-05-29 Laboratoire Français du Fractionnement et des Biotechnologies A von willebrand factor composition for use in treating a pathology mediated by angiogenesis
CN114249812B (en) * 2020-09-22 2023-09-15 四川远大蜀阳药业有限责任公司 Method for reducing IgM content in vWF (vWF) product

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61166542A (en) * 1985-01-18 1986-07-28 Hitachi Chem Co Ltd Photosensitive composition
US4970300A (en) * 1985-02-01 1990-11-13 New York University Modified factor VIII
US5006642A (en) * 1987-06-29 1991-04-09 Rhone-Poulenc Rorer Pharmaceuticals Inc. Purification of von Willebrand Factor by affinity chromatography
FR2632309B1 (en) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine PROCESS FOR THE CHROMATOGRAPHIC PURIFICATION OF PROTEINS, PARTICULARLY FACTOR VIII, AND THE PRODUCTS OBTAINED

Also Published As

Publication number Publication date
AU1113192A (en) 1992-09-10
NL300394I1 (en) 2009-09-01
EP0503991B1 (en) 1998-09-23
DE122009000034I1 (en) 2010-04-08
ITTO920189A1 (en) 1993-09-06
HU215098B (en) 1998-09-28
JPH0597696A (en) 1993-04-20
NO920867L (en) 1992-09-09
BR9200770A (en) 1992-11-17
ATA43692A (en) 2000-05-15
CA2062340A1 (en) 1992-09-09
UA27732C2 (en) 2000-10-16
EP0503991A1 (en) 1992-09-16
ES2121830T3 (en) 1998-12-16
JP3435668B2 (en) 2003-08-11
DE122009000034I2 (en) 2011-06-16
IT1256692B (en) 1995-12-12
FI106721B (en) 2001-03-30
FR2673632B1 (en) 1995-05-05
EG20300A (en) 1998-10-31
PL293738A1 (en) 1992-09-21
FI920992A (en) 1992-09-09
NZ241701A (en) 1994-10-26
HU9200767D0 (en) 1992-05-28
CS56892A3 (en) 1992-09-16
CZ283633B6 (en) 1998-05-13
AT407115B (en) 2000-12-27
ITTO920189A0 (en) 1992-03-06
EE03057B1 (en) 1997-12-15
CA2062340C (en) 2000-05-09
DE69227055D1 (en) 1998-10-29
IL101043A0 (en) 1992-11-15
NO301278B1 (en) 1997-10-06
DK0503991T3 (en) 1999-06-14
US5408039A (en) 1995-04-18
IL101043A (en) 1997-02-18
BE1004178A3 (en) 1992-10-06
DE69227055T2 (en) 1999-04-22
PL168353B1 (en) 1996-02-29
HUT63176A (en) 1993-07-28
FR2673632A1 (en) 1992-09-11
SK279533B6 (en) 1998-12-02
SA92120446B1 (en) 2004-05-04
RU2088590C1 (en) 1997-08-27
FI920992A0 (en) 1992-03-06
LT3175B (en) 1995-02-27
ZA921430B (en) 1992-11-25
AU645172B2 (en) 1994-01-06
NO920867D0 (en) 1992-03-05

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Legal Events

Date Code Title Description
PC9A Transfer of patents

Owner name: THE LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES

Effective date: 20090511

TC9A Change of representative

Representative=s name: ZABOLIENE, REDA, LT

MM9A Lapsed patents

Effective date: 20091230