LTIP264A - Composition for stabilizing blood plasma during pasteurization, method of pasteurization and plasma preparing by this method - Google Patents

Composition for stabilizing blood plasma during pasteurization, method of pasteurization and plasma preparing by this method

Info

Publication number
LTIP264A
LTIP264A LTIP264A LTIP264A LTIP264A LT IP264 A LTIP264 A LT IP264A LT IP264 A LTIP264 A LT IP264A LT IP264 A LTIP264 A LT IP264A LT IP264 A LTIP264 A LT IP264A
Authority
LT
Lithuania
Prior art keywords
pasteurization
plasma
composition
stabilizing blood
preparing
Prior art date
Application number
LTIP264A
Inventor
Miryana Burnouf
Thierry Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of LTIP264A publication Critical patent/LTIP264A/en
Publication of LT3419B publication Critical patent/LT3419B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A61L2103/09—Blood or products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Composition for stabilizing blood plasma, whole or lacking cryoproteins, during pasteurization. The composition according to the invention is used for pasteurizing substantial volumes of plasma (up to several hundreds of litres). The invention also concerns a process for the pasteurization of plasma using said stabilizing composition. The pasteurized plasma obtained is for therapeutic use.
LTIP264A 1990-07-03 1992-12-29 Composition for stabilizing blood plasma during pasteurization, method of pasteurization and plasma preparing by this method LT3419B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9008375A FR2664165B1 (en) 1990-07-03 1990-07-03 COMPOSITION FOR STABILIZING BLOOD PLASMA DURING PASTEURIZATION.

Publications (2)

Publication Number Publication Date
LTIP264A true LTIP264A (en) 1994-10-25
LT3419B LT3419B (en) 1995-09-25

Family

ID=9398269

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP264A LT3419B (en) 1990-07-03 1992-12-29 Composition for stabilizing blood plasma during pasteurization, method of pasteurization and plasma preparing by this method

Country Status (22)

Country Link
EP (1) EP0497929B1 (en)
JP (1) JP3132828B2 (en)
AT (1) ATE135238T1 (en)
AU (1) AU8062991A (en)
CA (1) CA2065284A1 (en)
CZ (1) CZ281431B6 (en)
DE (1) DE69117920T2 (en)
DK (1) DK0497929T3 (en)
ES (1) ES2084821T3 (en)
FI (1) FI96918C (en)
FR (1) FR2664165B1 (en)
GR (1) GR3020048T3 (en)
HU (1) HU208404B (en)
LT (1) LT3419B (en)
LV (1) LV10384B (en)
NO (1) NO179127C (en)
PL (1) PL166579B1 (en)
PT (1) PT98190B (en)
RU (1) RU2045902C1 (en)
SK (1) SK279031B6 (en)
WO (1) WO1992000767A1 (en)
ZA (1) ZA914848B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687317B1 (en) 1992-02-13 1995-06-23 Aetsrn COMPOSITION FOR STABILIZING BLOOD PLASMA DURING PASTEURIZATION AND PASTEURIZED PLASMATIC SOLUTION FOR THERAPEUTIC USE.
DE4240103A1 (en) * 1992-05-26 1993-12-02 Behringwerke Ag Process for inactivating viruses in protein preparations
DE19508192A1 (en) * 1995-03-09 1996-09-12 Behringwerke Ag Stable transglutaminase preparations and process for their preparation
US20060019234A1 (en) * 2004-07-22 2006-01-26 Shanbrom Technologies, Llc Modern blood banking employing improved cell preservation composition
WO2017155678A1 (en) 2016-03-10 2017-09-14 Kindheart, Inc Fake blood for use in simulated surgical procedures

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2916711A1 (en) 1979-04-25 1980-11-06 Behringwerke Ag Blood coagulation factors and process for their manufacture
DE3176491D1 (en) 1980-03-05 1987-11-26 Miles Lab Pasteurized therapeutically active protein compositions
DE3045153A1 (en) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg METHOD FOR THE PRODUCTION OF BLOOD COagulation FACTORS AND THE PREPARATION OF FACTORS IX AND X THEREFORE PRODUCED
DE3336631A1 (en) * 1983-10-08 1985-04-18 Behringwerke Ag, 3550 Marburg METHOD FOR THE PASTEURIZATION OF PLASMA OR CONCENTRATES OF THE BLOOD COAGINING FACTORS II, VII, IX AND X
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
DK18288D0 (en) * 1988-01-15 1988-01-15 Nordisk Gentofte PROCEDURE FOR PASTEURIZATION OF Aqueous SOLUTIONS OF FACTOR VIII

Also Published As

Publication number Publication date
PL166579B1 (en) 1995-06-30
EP0497929A1 (en) 1992-08-12
LV10384A (en) 1995-02-20
DK0497929T3 (en) 1996-07-22
FR2664165A1 (en) 1992-01-10
PL294037A1 (en) 1993-01-11
AU8062991A (en) 1992-02-04
CZ281431B6 (en) 1996-09-11
NO920791L (en) 1992-02-28
HUT60148A (en) 1992-08-28
DE69117920T2 (en) 1996-10-02
CS57992A3 (en) 1992-08-12
DE69117920D1 (en) 1996-04-18
ATE135238T1 (en) 1996-03-15
EP0497929B1 (en) 1996-03-13
HU9200701D0 (en) 1992-05-28
NO179127C (en) 1996-08-14
PT98190B (en) 1998-12-31
FI96918C (en) 1996-09-25
JPH05501417A (en) 1993-03-18
NO179127B (en) 1996-05-06
GR3020048T3 (en) 1996-08-31
RU2045902C1 (en) 1995-10-20
WO1992000767A1 (en) 1992-01-23
ES2084821T3 (en) 1996-05-16
NO920791D0 (en) 1992-02-28
HU208404B (en) 1993-10-28
JP3132828B2 (en) 2001-02-05
LT3419B (en) 1995-09-25
SK279031B6 (en) 1998-05-06
FI920934A0 (en) 1992-03-02
FI96918B (en) 1996-06-14
FR2664165B1 (en) 1992-10-16
CA2065284A1 (en) 1992-01-04
LV10384B (en) 1995-04-20
ZA914848B (en) 1992-04-29
PT98190A (en) 1992-05-29

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Effective date: 20111229