LT5958B - Additive for pets fodder - Google Patents

Abstract

The present invention relates to animal fodder, namely, to additive of fodder for pets. It aims to provide the additive which is useful for pet’s health, i.e., has anti-inflammatory, anti-bacterial, anti-microbial and anti-oxidative activity. The fodder additive claimed comprises micronized silicon-aluminum ceolite as additional component to rosemary and chicory, the component ratio being as follows, in weight %: micronized silicon-aluminum ceolite - 20-60, rosemary extract - 20-40, chicory roots extract - 20-40. The size of micronized silicon-aluminum ceolite particles is « 3 µm. The additive claimed has anti-inflammatory, anti-bacterial, anti-microbial and anti-oxidative activity.

Description

The invention relates to animal feeds, namely to pet food supplements.

In the field of animal nutrition, foods and supplements are very important because they contain important bioactive compounds that improve the health of the animal.

Zeolite deposits have been observed to attract flocks of wild animals that lick the rocks. The researchers found that the zeolite was like a sponge absorbing any liquid. It is used even to collect spilled oil and to improve soil composition. The natural material binds some toxic and heavy metals. Also very helpful in poisoning (MY FARM, Magazine 2005/4. Livestock).

The closest to the present invention is ARTEMIS Pet Food Co. Ine., US manufactured cat and dog food, ARTEMIS, which contains, among other products, chicory root and rosemary extract. However, these substances make up very small amounts in the overall product.

It is an object of the invention to supplement a dietary supplement which is beneficial to the health of the pet, i.e. have anti-inflammatory, antibacterial, antimicrobial and antioxidant properties.

The object is achieved by the addition of a micronized silicon-aluminum zeolite to the dietary supplement without rosemary and chicory in the following ratio of ingredients:

Micronised silicon-aluminum zeolite 20-60% by weight

Rosemary extract 20-40% by weight

Chicory root extract 20-40% by weight, wherein the micronized zeolite has a particle size of <= 3 µm, and wherein said additive has anti-inflammatory, antibacterial and antioxidant properties.

The following substances are used in the manufacture of the additive:

• Zeolites are natural or synthetic mesoporous and microporous crystals of silicate and aluminum silicate. They act as adsorbents, catalysts, ion exchangers. Also acts as an anti-diarrheal, non-specific immunostimulant. Standard milling of zeolite can reduce particle size and increase surface area. Dynamic milling or micronization at high rotational speeds results in sudden collisions of the particles, resulting in an increased proportion of the zeolite mesoporous surface. Such modifications improve the properties of the zeolite, such as improved adsorption capacity or ion retention capacity. Micronized Zeolite (MZ) acts as an effective, pharmaceutically acceptable, highly bioavailable source of silicon. MZ can release soluble silicon even in neutral water, possibly in the form of orthosilicic acid.

Uses micronized silicon-aluminum zeolite (MZ) of general formula: (Me ^{n +} ) _{x / n} [(AIO ₂ ) _x (SiO ₂ ) _y ] -mH ₂ O (MZ) where Me = Na, K, Mg, Ca , Fe, Zn, Mn, Cr; the silicon-aluminum ratio y: x ranges from 6: 1 to 1: 1 and has a particle size of <3 µm.

• As a natural antioxidant food supplement, rosemary extract contains Camosic Acid which:

- prevents lipid membrane changes due to oxidative stress or peroxidation,

- Reduces throat pathology and blood pressure in animals suffering from hypertension.

Carnosic acid, which is often found in rosemary, is a natural diterpene. Recently, various medical benefits of carnosic acid have been revealed: antineoplastic effects, inhibition of growth of various cancer cell lines; inhibition of oral squamous cell carcinoma, antimicrobial action, anti-inflammatory action, prevention of metabolic disorders in animals by reducing cholesterol, glycemia, obesity, etc.

Uses rosemary extract containing at least 2% rosemary acid (1) and 1.5% carnosic acid (2) in a concentration ranging from 20% to 40%.

OH • Chicory roots are rich in Inuine and sesquiterpene ectone. Inulin is known for its beneficial effects in constipation. It promotes healthy bowel function, stimulates bacterial growth, improves calcium and other nutrient uptake and improves overall health. Sesquiterpenic lactones in chicory determine its bitterness due to the use of chicory in parasite control.

The chicory root extract containing 0.5-15% sesquiterpenic lactones (3) has a concentration ranging from 20-40%;

The highly effective food supplement produced according to the present invention has improved antioxidant, anti-inflammatory, hepato-protective, antimicrobial and antiparasitic activity.

Studies show that the addition of a mixture of micronized zeolite, rosemary extract and chicory extract in animal feed and after feeding has been shown to be an extremely effective mixture for reducing triglyceride levels in animals. This can be explained by improved antioxidant activity.

The invention is illustrated by the following example:

Homogenize the micronized silicon - aluminum zeolite (400.00 g; 40%), rosemary extract (300.00 g; 30%) and chicory extract (300.00 g; 30%) in a dry homogenizer for 45 minutes. The resulting material is a pale yellow powder which is added as a pet food supplement.

TESTING Dogs of different breeds, ages and weights with diabetes mellitus (increased glucose, range 9.9 mmol / L - 14.4 mmol / L) and elevated triglycerides (range: 1.78 mmol / L - 3.24 mmol / L) were divided into two groups of 6 dogs. The first group was given 1 gram of a 1: 1 mixture (R + C) of rosemary extract and chicory extract for 10 days, added to standard dog food. The second group was given 1 gram of 10 kg body weight mixture consisting of 40% rosemary extract, 40% chicory extract and 20% MZ. This mixture was also added to standard dog food.

The standard meals for both groups consisted of:

Analytical constituents: 27% crude protein, 14% crude oils and fats, 5,2% crude ash, 2,2% crude fiber, 1,1% calcium, 0,9% phosphorus, 0% potassium, 5%, sodium 0.4%, fatty acids DHA + EPA 0.138%, taurine 0.065%, glucosamine 250 mg / kg, chondroitin -100 mg / kg.

Glucose and triglyceride levels were measured over four weeks on an IDEXX VetTest® chemical analyzer (IDEXX Dry-Slide Tecnology). We present results showing that R + C + MZ reduced triglyceride levels.

TABLE: Comparison of triglyceride levels at baseline and after 4 weeks

Dog Breed Age years Svo- ris kg TRIGLIC EREDOS initial quantity mmol / L (0 day) Glucose Initial Amount mmol / L (Day 0) TRIGLI- CERIDAI R + C GROUP mmol / L (Day 28) GLIU- COZY R + C GRU- ON THE FOOT mmol / L (28th day) 1 Mixed 12th 18th 1.83 9.6 1.76 9.12 2 Cocker Spaniel 8th 16th 2.01 11.1 1.87 10.43 3 Cocker Spaniel 10th 12th 1.78 9.4 1.71 8.55 4 German shepherd 6th 38 2.12 10.1 2.08 9.39 5 Bottle 14th 6th 2.44 12.3 2.32 11.32 6th Gold retriever 8th 42 3.01 14.3 2.77 13.01 AVERAGE RESULT 2.20 11.13 2.08 10.31 AVERAGE DECREASE 5.2% 7.4%

in the group to which R + C was added.

TABLE: Comparison of triglyceride levels at baseline and after 4 weeks in the R + C + MZ group.

Dog Breed Am- yeah me- at Svo- ris kg TRIGLIC ERIDAS initial quantity IN THE GROUP mmol / L (0 day) GLUCOSE INITIAL IN SOLUTION / L (Day 0) TRIGLI- CERIDAI R + C + MZ IN THE GROUP mmol / L (Day 28) GLUCO- ZE R + C + MZ GROUP mmol / L (Day 28) 1 Gold retriever 9th 44 1.78 9.3 1.48 7.35 2 Bottle 9th 7.5 2.01 10.7 1.59 8.03 3 Shichi 9th 9th 2.61 12.4 2.14 10.42 4 Cocker Spaniel is 9th 15.4 2.45 11.6 2.11 9.05 5 Retriver 9th 32 3.24 14.4 2.72 10.80 6th Mixed 9th 18th 1.84 9.7 1.51 7.86 AVERAGE RESUL1 'ATAS 2.32 11.35 1.92 8.92 AVERAGE DECREASE 17.1% 21.4%

Thus, the effects of micronized silicon-aluminum zeolite (MZ), rosemary extract and chicory root extract are as follows:

- highly bioactive silicon (from MZ) has anti-inflammatory action;

- orthosilicic acid (from MZ) forms relatively stable complexes with rosemary acid and carnosic acid and sesquiterpenic lactones.

- Ultra-fine MZ particles form complexes with extracts and act as slow release agents for improved extracts.

Claims (3)

1. Pet food supplement containing rosemary and chicory root extracts, characterized in that the supplement comprises micronized siliconium zeolite, rosemary extract and chicory root extract in the following ratio of ingredients: micronized silicon-aluminum zeolite 20-60% by weight rosemary extract 20-40% by weight chicory root extract 20-40% by weight 2. Additive according to claim 1, characterized in that the micronized silicon-aluminum zeolite has a particle size <= 3 µm. 3. An additive according to claim 1, which has anti-inflammatory, antibacterial and antioxidant properties.