LT3628319T - Treatment of hepatic encephalopathy using rifaximin - Google Patents
Treatment of hepatic encephalopathy using rifaximinInfo
- Publication number
- LT3628319T LT3628319T LTEP19207534.9T LT19207534T LT3628319T LT 3628319 T LT3628319 T LT 3628319T LT 19207534 T LT19207534 T LT 19207534T LT 3628319 T LT3628319 T LT 3628319T
- Authority
- LT
- Lithuania
- Prior art keywords
- rifaximin
- treatment
- hepatic encephalopathy
- encephalopathy
- hepatic
- Prior art date
Links
- 208000007386 hepatic encephalopathy Diseases 0.000 title 1
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 title 1
- 229960003040 rifaximin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Emergency Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10234908P | 2008-10-02 | 2008-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3628319T true LT3628319T (en) | 2024-03-25 |
Family
ID=42073897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP19207534.9T LT3628319T (en) | 2008-10-02 | 2009-10-02 | Treatment of hepatic encephalopathy using rifaximin |
| LTEP09818544.0T LT2350096T (en) | 2008-10-02 | 2009-10-02 | Methods of treating hepatic encephalopathy |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP09818544.0T LT2350096T (en) | 2008-10-02 | 2009-10-02 | Methods of treating hepatic encephalopathy |
Country Status (20)
| Country | Link |
|---|---|
| US (11) | US20100204173A1 (en) |
| EP (2) | EP2350096B1 (en) |
| JP (2) | JP6037615B2 (en) |
| CN (1) | CN102245615A (en) |
| AU (1) | AU2009298389C1 (en) |
| BR (1) | BRPI0920465A2 (en) |
| CA (1) | CA2739436C (en) |
| CY (1) | CY1122806T1 (en) |
| DK (2) | DK2350096T3 (en) |
| ES (1) | ES2770308T3 (en) |
| FI (1) | FI3628319T3 (en) |
| HR (1) | HRP20200284T1 (en) |
| HU (1) | HUE048293T2 (en) |
| IL (1) | IL212055A0 (en) |
| LT (2) | LT3628319T (en) |
| MX (2) | MX364102B (en) |
| PL (2) | PL3628319T3 (en) |
| PT (2) | PT3628319T (en) |
| SI (2) | SI3628319T1 (en) |
| WO (1) | WO2010040020A1 (en) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| DK1698630T3 (en) | 2005-03-03 | 2014-12-08 | Alfa Wassermann Spa | Novel polymorphic forms of rifaximin, methods for their preparation and their use in the medical preparations |
| US7928115B2 (en) | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| US20110035232A1 (en) | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| WO2010040020A1 (en) * | 2008-10-02 | 2010-04-08 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| EP3964066A1 (en) * | 2009-06-02 | 2022-03-09 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| AU2010260089B2 (en) * | 2009-06-15 | 2015-05-14 | Salix Pharmaceuticals, Inc. | Modulation of systemic exposure to rifaximin |
| US8772242B2 (en) | 2009-10-26 | 2014-07-08 | Thomas Julius Borody | Therapy for enteric infections |
| CN103124559B (en) | 2010-08-04 | 2017-03-29 | 托马斯·朱利叶斯·波洛迪 | For the device of the compositionss and its preparation and application and delivering said composition of faecal microbiota implantation |
| WO2012076832A1 (en) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
| CA3119918A1 (en) | 2011-03-09 | 2012-09-13 | Regents Of The University Of Minnesota | Compositions and methods for transplantation of colon microbiota |
| WO2013067394A1 (en) | 2011-11-02 | 2013-05-10 | Salix Pharmaceuticals, Ltd | Methods for treating irritable bowel syndrome (ibs) and infections |
| WO2013176774A1 (en) | 2012-05-25 | 2013-11-28 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| ITBO20120368A1 (en) * | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | COMPOSITIONS INCLUDING RIFAXIMINA AND AMINO ACIDS, RIFAXIMINE CRYSTALS DERIVING FROM SUCH COMPOSITIONS AND THEIR USE. |
| CA2883851A1 (en) * | 2012-09-13 | 2014-03-20 | Salix Pharmaceuticals, Inc. | Methods of improving long-term survival and reducing hospitalization readmission rates for subjects suffering from hepatic encephalopathy |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US20150335615A1 (en) * | 2013-01-04 | 2015-11-26 | Toshihisa Kawai | Cholesterol-lowering compounds in combination with lipid metabolism-altering compounds of non-absorbable sugars, compounds that convert nh3 to nh4+, or hydrogen-generating compounds for the treatment of high cholesterol and inflammation |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| WO2014176632A1 (en) * | 2013-04-30 | 2014-11-06 | Borody Thomas J | Compositions and methods for treating microbiota-related psychotropic conditions and diseases |
| CN103340856A (en) * | 2013-07-09 | 2013-10-09 | 荣港生技医药科技（北京）有限公司 | Rifaximin medicine composition and preparation method thereof |
| JP6543633B2 (en) | 2014-01-29 | 2019-07-10 | ウメクライン コグニション アーベー | Steroid compounds for use in the treatment of hepatic encephalopathy |
| ES2621557T3 (en) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Polymorphic mixture of rifaximin and its use for the preparation of solid formulations |
| ES2810010T3 (en) | 2014-05-12 | 2021-03-08 | Alfasigma Spa | Preparation and use of the tau crystalline form of rifaximin solvated with DEGME |
| WO2016003536A1 (en) * | 2014-06-30 | 2016-01-07 | Salix Pharmaceuticals, Inc. | Methods for retreating irritable bowel syndrome (ibs) |
| TWI748936B (en) | 2015-01-12 | 2021-12-11 | 瑞典商優鎂奎認知Ａｂ公司 | Novel compounds |
| EP3294307A4 (en) | 2015-05-14 | 2019-01-23 | Crestovo Holdings Llc | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| CA2986485A1 (en) | 2015-05-22 | 2016-12-01 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| CA3010865A1 (en) * | 2016-01-08 | 2017-07-13 | Colonaryconcepts Llc | Food based delivery of therapeutic agent for treatment of hepatic encephalopathy |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| EP4137132A1 (en) | 2016-09-30 | 2023-02-22 | Salix Pharmaceuticals, Inc. | Solid dispersion forms of rifaximin |
| US11026978B2 (en) | 2016-10-11 | 2021-06-08 | Finch Therapeutics Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| WO2018071536A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating primary sclerosing cholangitis and related disorders |
| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| CN106822125A (en) * | 2017-02-28 | 2017-06-13 | 丹诺医药(苏州）有限公司 | A kind of new application of rifamycin quinolizine ketone dual-target molecule |
| CN106822119A (en) * | 2017-02-28 | 2017-06-13 | 丹诺医药(苏州）有限公司 | A kind of new application of rifamycin nitroimidazole coupling molecule |
| US11433102B2 (en) | 2017-04-05 | 2022-09-06 | Finch Therapeutics Holdings Llc | Compositions and methods for treating Parkinson's disease (PD) and related disorders |
| US11040073B2 (en) | 2017-04-05 | 2021-06-22 | Finch Therapeutics Holdings Llc | Compositions and methods for treating diverticulitis and related disorders |
| WO2018218159A1 (en) | 2017-05-26 | 2018-11-29 | Crestovo Holdings Llc | Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same |
| EP3664823B1 (en) | 2017-08-07 | 2024-06-05 | Finch Therapeutics Holdings LLC | Composition for use in preventing or treating an enterococcal blood stream infection |
| JP2021502382A (en) | 2017-11-10 | 2021-01-28 | コスモ・テクノロジーズ・リミテツド | Oral Rifamycin SV Composition |
| US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
| CA3114423A1 (en) | 2018-09-27 | 2020-04-02 | Finch Therapeutics Holdings Llc | Compositions and methods for treating epilepsy and related disorders |
| AU2020276213A1 (en) | 2019-05-10 | 2021-10-28 | Société des Produits Nestlé S.A. | Methods for improving the quality of life of a patient with a peanut allergy |
| US20230111568A1 (en) * | 2020-03-24 | 2023-04-13 | Bausch Health Ireland Limited | Solid dispersions of rifaximin for the treatment of overt hepatic encephalopathy |
| WO2023225073A1 (en) * | 2022-05-18 | 2023-11-23 | Virginia Commonwealth University | Methods for treatment of cognitive impairment in cirrhosis patients |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3132910A (en) | 1962-03-26 | 1964-05-12 | Eastman Kodak Co | Cabinetry structure |
| IT1154655B (en) | 1980-05-22 | 1987-01-21 | Alfa Farmaceutici Spa | IMIDAZO-RIFAMYCIN DERIVATIVES METHODS FOR THEIR PREPARATION AND USE AS AN ANTIBACTERIAL ACTION SUBSTANCE |
| US4343785A (en) | 1981-08-10 | 1982-08-10 | Basf Wyandotte Corporation | Gel dentifrice compositions |
| IT1199374B (en) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | PROCESS FOR THE PREPARATION OF PIRIDO-IMIDAZO-RIFAMICINE |
| AU5171293A (en) | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
| IT1264494B1 (en) | 1993-03-23 | 1996-09-24 | Alfa Wassermann Spa | USE OF RIFAXIMIN AND FORMULATIONS THAT CONTAIN IT IN THE TREATMENT OF GASTRIC DYSPEPSIES ORIGINATED BY HELICOBACTER |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US6562629B1 (en) * | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
| ES2114502B1 (en) | 1996-07-29 | 1999-07-01 | Univ Santiago Compostela | APPLICATION OF NANOPARTICLES BASED ON HYDROPHILIC POLYMERS AS PHARMACEUTICAL FORMS. |
| WO1998010649A1 (en) | 1996-09-13 | 1998-03-19 | University Technology Corporation | Biocompatible cationic detergents and uses therefor |
| IT1290679B1 (en) | 1997-02-14 | 1998-12-10 | Alfa Wassermann Spa | USE OF RIFAXIMINE AND OF THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT IN THE TREATMENT OF DIARRHEA FROM CRYPTOSPORIDIOSIS. |
| US20020028764A1 (en) | 2000-09-04 | 2002-03-07 | Aarhus Amt. | Treatment of acute and chronic liver disease |
| GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
| US20040229948A1 (en) * | 2002-04-12 | 2004-11-18 | Summar Marshall L. | Method for preventing hepatic encephalopathic episodes |
| US20040077533A1 (en) * | 2002-05-23 | 2004-04-22 | Sayada Chalom B. | Methods and compositions for treating bacterial infections and diseases associated therewith |
| US20090149453A1 (en) * | 2002-05-23 | 2009-06-11 | Activbiotics Pharma Llc | Methods and compositions for treating bacterial infections and diseases associated therewith |
| ATE448775T1 (en) * | 2002-08-29 | 2009-12-15 | Activbiotics Pharma Llc | RIFALAZIL FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTIONS |
| TW200418485A (en) * | 2002-09-23 | 2004-10-01 | Activbiotics Inc | Rifalazil compositions and therapeutic regimens |
| ITMI20032144A1 (en) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | REFLEXIMINE POLIMORPHIC FORMS, PROCESSES TO OBTAIN THEM AND |
| US7906542B2 (en) | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
| US7902206B2 (en) | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
| US7256202B2 (en) | 2003-12-31 | 2007-08-14 | Halow George M | Composition and method for treatment of hepatic encephalopathy |
| EP2319581B1 (en) | 2004-11-26 | 2015-02-25 | UCL Business PLC | Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy |
| US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
| DK1698630T3 (en) * | 2005-03-03 | 2014-12-08 | Alfa Wassermann Spa | Novel polymorphic forms of rifaximin, methods for their preparation and their use in the medical preparations |
| US20090233888A1 (en) | 2005-03-23 | 2009-09-17 | Usc Stevens, University Of Southern California | Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth |
| WO2007103448A2 (en) | 2006-03-09 | 2007-09-13 | Salix Pharmaceuticals, Inc. | Rifaximin anti-rectal dysfunction preparation |
| AU2007275034A1 (en) | 2006-07-21 | 2008-01-24 | Lab International Srl | Hydrophilic abuse deterrent delivery system |
| CN104382900A (en) | 2006-08-02 | 2015-03-04 | 萨利克斯药品公司 | Compositions and methods for the treatment of radiation proctosigmoitis |
| CN101534840A (en) | 2006-08-02 | 2009-09-16 | 萨利克斯药品公司 | Methods for the treatment of radiation proctosigmoitis |
| US8633234B2 (en) | 2006-09-22 | 2014-01-21 | Cipla Limited | Rifaximin |
| US20100136125A1 (en) | 2006-12-28 | 2010-06-03 | Jacobus Pharmaceutical Company, Inc. | Method of treating inflammatory bowel disease |
| SI2011486T1 (en) | 2007-07-06 | 2012-10-30 | Lupin Ltd | Pharmaceutical compositions of rifaximin |
| WO2009008005A1 (en) * | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions of rifaximin |
| UA101829C2 (en) * | 2008-02-25 | 2013-05-13 | Саликс Фармасьютикалз, Лтд. | Forms of rifaximin and uses thereof in therapy |
| US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
| PL2252148T3 (en) | 2008-02-26 | 2019-09-30 | Salix Pharmaceuticals, Ltd. | Methods for treating irritable bowel syndrome |
| WO2010040020A1 (en) * | 2008-10-02 | 2010-04-08 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| US7928115B2 (en) * | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| US20100317681A1 (en) | 2009-06-15 | 2010-12-16 | Salix Pharmaceuticals, Ltd. | Modulation of systemic exposure to rifaximin |
| US20110035232A1 (en) | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| EP3964066A1 (en) | 2009-06-02 | 2022-03-09 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| DE102009052972A1 (en) | 2009-11-12 | 2011-09-15 | Lts Lohmann Therapie-Systeme Ag | Process for preventing the crystallization of drugs in a polymer film |
| EP2340812A1 (en) | 2009-12-18 | 2011-07-06 | Ferring International Center S.A. | Granules for pharmaceutical preparations, methods and apparatus for their production |
| LT2608792T (en) | 2010-08-26 | 2018-01-10 | Boehringer Ingelheim International Gmbh | Methods of administering an egfr inhibitor |
| KR20130027255A (en) * | 2011-09-07 | 2013-03-15 | 삼성전자주식회사 | Key assembly and rotary input device using the same |
| PT2785349T (en) | 2011-11-30 | 2019-12-11 | Astrazeneca Ab | Combination treatment of cancer |
| CN106462181B (en) | 2014-04-29 | 2019-10-25 | 惠普发展公司，有限责任合伙企业 | Hinge assembly for computing device |
| US20160191956A1 (en) * | 2014-12-15 | 2016-06-30 | Cable Television Laboratories, Inc. | Software defined networking in a cable tv system |
| SI3302565T1 (en) | 2015-06-04 | 2020-02-28 | Pfizer Inc. | Solid dosage forms of palbociclib |
-
2009
- 2009-10-02 WO PCT/US2009/059321 patent/WO2010040020A1/en active Application Filing
- 2009-10-02 CN CN2009801490791A patent/CN102245615A/en active Pending
- 2009-10-02 MX MX2014013652A patent/MX364102B/en unknown
- 2009-10-02 ES ES09818544T patent/ES2770308T3/en active Active
- 2009-10-02 LT LTEP19207534.9T patent/LT3628319T/en unknown
- 2009-10-02 PT PT192075349T patent/PT3628319T/en unknown
- 2009-10-02 LT LTEP09818544.0T patent/LT2350096T/en unknown
- 2009-10-02 MX MX2011003548A patent/MX2011003548A/en active IP Right Grant
- 2009-10-02 AU AU2009298389A patent/AU2009298389C1/en active Active
- 2009-10-02 PL PL19207534.9T patent/PL3628319T3/en unknown
- 2009-10-02 HU HUE09818544A patent/HUE048293T2/en unknown
- 2009-10-02 US US12/572,344 patent/US20100204173A1/en not_active Abandoned
- 2009-10-02 PT PT98185440T patent/PT2350096T/en unknown
- 2009-10-02 EP EP09818544.0A patent/EP2350096B1/en active Active
- 2009-10-02 CA CA2739436A patent/CA2739436C/en active Active
- 2009-10-02 JP JP2011530261A patent/JP6037615B2/en active Active
- 2009-10-02 DK DK09818544.0T patent/DK2350096T3/en active
- 2009-10-02 SI SI200932192T patent/SI3628319T1/en unknown
- 2009-10-02 BR BRPI0920465-2A patent/BRPI0920465A2/en not_active Application Discontinuation
- 2009-10-02 FI FIEP19207534.9T patent/FI3628319T3/en active
- 2009-10-02 DK DK19207534.9T patent/DK3628319T3/en active
- 2009-10-02 SI SI200932045T patent/SI2350096T1/en unknown
- 2009-10-02 EP EP19207534.9A patent/EP3628319B1/en active Active
- 2009-10-02 PL PL09818544T patent/PL2350096T3/en unknown
-
2011
- 2011-03-31 US US13/077,373 patent/US20110243879A1/en not_active Abandoned
- 2011-03-31 IL IL212055A patent/IL212055A0/en active IP Right Grant
-
2013
- 2013-02-15 US US13/768,617 patent/US8969398B2/en active Active
-
2015
- 2015-02-03 US US14/612,697 patent/US9629829B2/en active Active
- 2015-05-21 JP JP2015103724A patent/JP2015166381A/en active Pending
-
2017
- 2017-03-16 US US15/460,704 patent/US9949958B2/en active Active
-
2018
- 2018-03-15 US US15/922,010 patent/US10335397B2/en active Active
-
2019
- 2019-05-16 US US16/414,018 patent/US10709694B2/en active Active
-
2020
- 2020-02-19 HR HRP20200284TT patent/HRP20200284T1/en unknown
- 2020-02-21 CY CY20201100167T patent/CY1122806T1/en unknown
- 2020-06-05 US US16/893,651 patent/US20200368213A1/en not_active Abandoned
-
2021
- 2021-03-26 US US17/213,678 patent/US11633384B2/en active Active
-
2023
- 2023-03-06 US US18/117,899 patent/US20240066010A1/en active Pending
- 2023-04-18 US US18/135,823 patent/US20230330071A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI3628319T3 (en) | Treatment of hepatic encephalopathy using rifaximin | |
| IL208354A0 (en) | Methods of treatment | |
| GB0818074D0 (en) | Treatment of biofilms | |
| ZA201102604B (en) | Alkylcyclohexylethers of dihydrotetraazabenzoazulenes | |
| EP2437603A4 (en) | Methods of treating hepatic encephalopathy | |
| PL2133419T3 (en) | Uses of cyanophycin beta-dipeptides | |
| PL2328545T3 (en) | Use of glucosylglycerol | |
| HK1160925A1 (en) | Use of athepsin | |
| EP2184353A4 (en) | Treatment of influenza | |
| GB0821596D0 (en) | Shower attachment | |
| GB0723100D0 (en) | Treatment of HFnEF | |
| EP2331490A4 (en) | Preparation of dibutoxymethane | |
| GB2462856B (en) | Shower assemblies | |
| GB0821710D0 (en) | Derivatives of dihydroindolone | |
| GB2465211B (en) | Treatment Solution | |
| GB0804468D0 (en) | Treatment of influenza | |
| PL386302A1 (en) | New derivative of isothiazolopyridine | |
| AU321800S (en) | Hand shower | |
| AU325461S (en) | Hand shower | |
| GB0704989D0 (en) | Treatment of influenza | |
| GB0814259D0 (en) | Shower enclosure | |
| HU0800656D0 (en) | Effective use of tea-composition | |
| EP2304140A4 (en) | Lock of slam- latch type | |
| GB0809319D0 (en) | The treatment of puritus | |
| AU325861S (en) | Towel |