LT3352752T - Detecting and treating growth hormone deficiency - Google Patents

Detecting and treating growth hormone deficiency

Info

Publication number
LT3352752T
LT3352752T LTEPPCT/US2016/052800T LT16052800T LT3352752T LT 3352752 T LT3352752 T LT 3352752T LT 16052800 T LT16052800 T LT 16052800T LT 3352752 T LT3352752 T LT 3352752T
Authority
LT
Lithuania
Prior art keywords
detecting
growth hormone
hormone deficiency
treating growth
treating
Prior art date
Application number
LTEPPCT/US2016/052800T
Other languages
Lithuanian (lt)
Inventor
Michael THORNER
Original Assignee
Lumos Pharma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumos Pharma Inc. filed Critical Lumos Pharma Inc.
Publication of LT3352752T publication Critical patent/LT3352752T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/61Growth hormones [GH] (Somatotropin)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/65Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
LTEPPCT/US2016/052800T 2015-09-21 2016-09-21 Detecting and treating growth hormone deficiency LT3352752T (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562221191P 2015-09-21 2015-09-21
US201662289221P 2016-01-30 2016-01-30
PCT/US2016/052800 WO2017053373A1 (en) 2015-09-21 2016-09-21 Detecting and treating growth hormone deficiency

Publications (1)

Publication Number Publication Date
LT3352752T true LT3352752T (en) 2022-04-11

Family

ID=58276481

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2016/052800T LT3352752T (en) 2015-09-21 2016-09-21 Detecting and treating growth hormone deficiency

Country Status (23)

Country Link
US (3) US9763919B2 (en)
EP (3) EP3352752B1 (en)
JP (4) JP6816149B2 (en)
KR (3) KR102560838B1 (en)
CN (2) CN116459250A (en)
AU (4) AU2016328969B2 (en)
CA (1) CA2998523C (en)
CY (1) CY1125183T1 (en)
DK (2) DK3939590T3 (en)
ES (2) ES2967259T3 (en)
FI (1) FI3939590T3 (en)
HK (1) HK1263178A1 (en)
HR (1) HRP20220317T1 (en)
HU (2) HUE065224T2 (en)
IL (1) IL258224B (en)
LT (1) LT3352752T (en)
PL (2) PL3939590T3 (en)
PT (2) PT3352752T (en)
RS (1) RS62988B1 (en)
SG (2) SG10201902424TA (en)
SI (1) SI3352752T1 (en)
UA (1) UA123865C2 (en)
WO (1) WO2017053373A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11234969B2 (en) * 2016-01-30 2022-02-01 Lumos Pharma, Inc. Detecting and treating growth hormone deficiency
PL3939590T3 (en) * 2015-09-21 2024-03-25 Lumos Pharma, Inc. Detecting and treating growth hormone deficiency
US10288629B1 (en) * 2017-12-19 2019-05-14 Aeterna Zentaris, Inc. Method of assessing growth hormone deficiency in humans by a macimorelin containing composition
US11644474B2 (en) * 2020-07-22 2023-05-09 Æterna Zentaris Gmbh Use of macimorelin in assessing growth hormone deficiency in children
WO2024096892A1 (en) * 2022-11-03 2024-05-10 Lumos Pharma, Inc. Compactable oral formulations of ibutamoren

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000759A1 (en) * 1992-06-29 1994-01-06 University Of South Florida Diagnostic procedure for evaluating short stature etiology
US5756507A (en) 1995-12-14 1998-05-26 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
DE69836386T2 (en) * 1997-08-22 2007-10-11 Kaken Pharmaceutical Co., Ltd. Amides to promote the secretion of growth hormones
ES2333097T3 (en) * 2000-05-31 2010-02-17 Raqualia Pharma Inc USE OF SECRETAGOGS OF GROWTH HORMONE TO STIMULATE GASTROINTESTINAL MOTILITY.
ATE302181T1 (en) 2000-06-13 2005-09-15 Zentaris Gmbh COMPOUNDS FOR STIMULATING THE SECRETION OF GROWTH HORMONES
JP2007505892A (en) * 2003-09-19 2007-03-15 ファイザー・ヘルス・アクティエボラーグ Improved treatment for growth disorders
KR20070054762A (en) * 2003-11-12 2007-05-29 페노믹스 코포레이션 Heterocyclic boronic acid compounds
GB0603295D0 (en) 2006-02-18 2006-03-29 Ardana Bioscience Ltd Methods and kits
WO2013163455A2 (en) * 2012-04-25 2013-10-31 The Regents Of The University Of California A drug screening platform for rett syndrome
PL3939590T3 (en) * 2015-09-21 2024-03-25 Lumos Pharma, Inc. Detecting and treating growth hormone deficiency

Also Published As

Publication number Publication date
EP3939590B1 (en) 2023-11-29
JP2018529766A (en) 2018-10-11
IL258224A (en) 2018-05-31
AU2021254600A1 (en) 2021-11-18
DK3352752T3 (en) 2022-02-28
KR20230116961A (en) 2023-08-04
CN116459250A (en) 2023-07-21
EP3939590A1 (en) 2022-01-19
US20190015394A1 (en) 2019-01-17
UA123865C2 (en) 2021-06-16
JP7104768B2 (en) 2022-07-21
PT3352752T (en) 2022-03-09
SI3352752T1 (en) 2022-05-31
EP3352752A4 (en) 2019-06-12
ES2967259T3 (en) 2024-04-29
HRP20220317T1 (en) 2022-05-13
JP6816149B2 (en) 2021-01-20
ES2908423T3 (en) 2022-04-29
CN108348501A (en) 2018-07-31
RS62988B1 (en) 2022-03-31
SG10202010598SA (en) 2020-11-27
KR102385669B1 (en) 2022-04-13
AU2024201658A1 (en) 2024-04-04
FI3939590T3 (en) 2023-12-14
AU2016328969A1 (en) 2018-04-26
US20170079961A1 (en) 2017-03-23
AU2020233715A1 (en) 2020-10-22
JP2021063096A (en) 2021-04-22
DK3939590T3 (en) 2023-12-18
EP4296679A2 (en) 2023-12-27
US10898472B2 (en) 2021-01-26
JP7389862B2 (en) 2023-11-30
WO2017053373A1 (en) 2017-03-30
US9763919B2 (en) 2017-09-19
PL3352752T3 (en) 2022-04-19
EP4296679A3 (en) 2024-04-10
CA2998523A1 (en) 2017-03-30
US20180071266A1 (en) 2018-03-15
AU2021254600B2 (en) 2024-02-15
PT3939590T (en) 2024-01-23
KR20220047407A (en) 2022-04-15
CY1125183T1 (en) 2023-06-09
IL258224B (en) 2021-10-31
HUE065224T2 (en) 2024-05-28
JP2022163012A (en) 2022-10-25
EP3352752B1 (en) 2021-12-22
CA2998523C (en) 2023-08-01
HK1263178A1 (en) 2020-01-31
EP3352752A1 (en) 2018-08-01
KR102560838B1 (en) 2023-07-27
AU2020233715B2 (en) 2021-09-30
SG10201902424TA (en) 2019-04-29
HUE057831T2 (en) 2022-06-28
KR20180082428A (en) 2018-07-18
PL3939590T3 (en) 2024-03-25
AU2016328969B2 (en) 2020-10-08
US10105352B2 (en) 2018-10-23
JP2024026112A (en) 2024-02-28

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