KR970073593A - Anticancer composition containing ginsenoside Rg_5 - Google Patents

Anticancer composition containing ginsenoside Rg_5 Download PDF

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Publication number
KR970073593A
KR970073593A KR1019960019281A KR19960019281A KR970073593A KR 970073593 A KR970073593 A KR 970073593A KR 1019960019281 A KR1019960019281 A KR 1019960019281A KR 19960019281 A KR19960019281 A KR 19960019281A KR 970073593 A KR970073593 A KR 970073593A
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KR
South Korea
Prior art keywords
ginseng
ginsenoside
present
composition according
anticancer composition
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Application number
KR1019960019281A
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Korean (ko)
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KR0183448B1 (en
Inventor
박만기
이숭기
박정일
김종문
이광열
한상범
Original Assignee
박만기
손경식
이승기
제일제당 주식회사
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Priority to KR1019960019281A priority Critical patent/KR0183448B1/en
Publication of KR970073593A publication Critical patent/KR970073593A/en
Application granted granted Critical
Publication of KR0183448B1 publication Critical patent/KR0183448B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)

Abstract

본 발명은 인삼의 성분중의 하나인 진세노사이드Rg5를 활성성분으로 함유한느 항암제 조성물에 관한 것이다. 본 발명에 따르는 조성물의 활성성분인 진세노사이드Rg5는 수삼, 백삼 등의 인삼식물에는 거의 존재하지 않고 홍삼중에 극미량으로만 존재하는 성분으로, 인삼식물을 110 내지 180℃의 고온에서 0.5 내지 20시간 동안 가열함으로써 그 함량이 현저히 증가하는 성분으로서, 강력한 항암활성, 특히 간암세포에 대해 강력한 항암활성을 나타낸다.The present invention relates to an anticancer agent composition containing ginsenoside Rg 5 as one of the components of ginseng as an active ingredient. Ginsenoside Rg 5 , the active ingredient of the composition according to the present invention, is present in the ginseng plants such as ginseng and white ginseng, and is present only in trace amounts in red ginseng. As a component whose content is significantly increased by heating for a time, it exhibits strong anticancer activity, particularly strong anticancer activity against liver cancer cells.

Description

진세노사이드 Rg5를 함유하는 항암제 조성물.An anticancer composition containing ginsenoside Rg5.

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (5)

활성성분으로서 진세노사이드 Rg5를 함유하는 항암제 조성물.An anticancer composition containing ginsenoside Rg 5 as an active ingredient. 제1항에 있어서, 활성성분인 진세노사이드 Rg5가 순수한 Rg5또는 Rg5를 10% 이상 함유하는 인삼 추출물임을 특징으로 하는 항암제 조성물.The anticancer composition according to claim 1, wherein the active ginsenoside Rg 5 is ginseng extract containing 10% or more of pure Rg 5 or Rg 5 . 제1항에 있어서, 약제학적으로 허용되는 담체와 함께 단위투여형으로 제형화됨을 특징으로 하는 항암제 조성물.The anticancer agent composition according to claim 1, which is formulated in a unit dosage form with a pharmaceutically acceptable carrier. 제3항에 있어서, 단위투여형 약제학적 제형이 정제, 경질 또는 연질캅셀제, 과립제, 액제, 현탁제, 주사용 용액 또는 현탁액임을 특징으로 하는 항암제 조성물.4. The anticancer composition according to claim 3, wherein the unit dosage form is a tablet, hard or soft capsule, granule, liquid, suspension, injectable solution or suspension. 제4항에 있어서, 단위투여형이 진세노사이드 Rg510 내지 500mg을 함유하도록 제형화됨을 특징으로 하는 항암제 조성물.The anticancer composition according to claim 4, wherein the unit dosage form is formulated to contain 10 to 500 mg of ginsenoside Rg 5 . ※ 참고사항：최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019960019281A 1996-05-31 1996-05-31 Anti-carcinogenic composition containing ginsenoside rg5 KR0183448B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019960019281A KR0183448B1 (en) 1996-05-31 1996-05-31 Anti-carcinogenic composition containing ginsenoside rg5

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019960019281A KR0183448B1 (en) 1996-05-31 1996-05-31 Anti-carcinogenic composition containing ginsenoside rg5

Publications (2)

Publication Number Publication Date
KR970073593A true KR970073593A (en) 1997-12-10
KR0183448B1 KR0183448B1 (en) 1999-05-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960019281A KR0183448B1 (en) 1996-05-31 1996-05-31 Anti-carcinogenic composition containing ginsenoside rg5

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KR (1) KR0183448B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005020715A1 (en) * 2003-08-28 2005-03-10 Neo Bio Co., Ltd. Method of improving the content of anticancer substances in ginseng
KR100676869B1 (en) * 2005-05-10 2007-02-02 신중엽 Preparation method of functional composition from the extracts of Phellinus linteus and processed ginseng and the preparation method of functional tea using the same

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020042212A (en) * 2000-11-30 2002-06-05 윤택구 Cancer preventive composition comprising ginsenoside glycosides of red ginseng
KR100485936B1 (en) * 2002-10-23 2005-04-27 주식회사 바이오사포젠 Anticarcinogenic constituents of ginsenoside Rh2 and Rg3
CN100563668C (en) * 2003-08-18 2009-12-02 株式会社柳柳 Use the gen-seng and the processing thereof of vinegar
KR100665087B1 (en) * 2004-12-07 2007-01-04 주식회사 진생사이언스 Composition comprising ginsenoside Rg5 and Rk1 for improving brain function and memory dysfunction

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005020715A1 (en) * 2003-08-28 2005-03-10 Neo Bio Co., Ltd. Method of improving the content of anticancer substances in ginseng
KR100676869B1 (en) * 2005-05-10 2007-02-02 신중엽 Preparation method of functional composition from the extracts of Phellinus linteus and processed ginseng and the preparation method of functional tea using the same

Also Published As

Publication number Publication date
KR0183448B1 (en) 1999-05-01

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